人与鼠阿尔茨海默氏症Aβ蛋白错误折叠机理的比较研究

30800184
2008
C0505.蛋白质、多肽与酶生物化学
申亮
青年科学基金项目
教授
山东理工大学
20万元
阿尔茨海默氏症;错误折叠;量子化学计算;β-淀粉样蛋白;分子动力学模拟
2009-01-01到2011-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Mechanistic Study of ROS-photogeneration by Pterin 期刊论文 Ji Hong-Fang |Shen Liang |
2 Berberine: a potential multipotent natural product to combat Alzheimer's disease 期刊论文 Ji Hong-Fang |Shen Liang |
3 Theoretical Study on Reactions of Triplet Excited State Thioxanthone with Indole 期刊论文 Ji Hong-Fang |Shen Liang |
4 Molecular Basis of Inhibitory Activities of Berberine against Pathogenic Enzymes in Alzheimer’s Disease 期刊论文 Ji Hong-Fang |Shen Liang |
5 On photoprotective mechanisms of carotenoids in light harvesting complex 期刊论文 Shen Liang |Xiao Fu-Gui |Ji Hong-Fang |
6 A meta-analysis of tea drinking and risk of Parkinson’s disease 期刊论文 Ji Hong-Fang |Shen Liang |Li Feng-Jiao |
7 基于天然产物的药物设计策略 奖励 申亮|纪洪芳|
8 β-sheet constitution of prion protein 期刊论文 Hong-Yu Zhang|Hong-Fang Ji|
9 Density functional theory study of the photosensitization mechanisms of indigo 期刊论文 Liang Shen|Hong-Fang Ji|
10 Mechanistic insight into the DPPH radical-scavenging activity of hydroxystilbene derivatives 期刊论文 Shen Liang |
11 Conformational conversion and prion disease 期刊论文 Ji Hong-Fang |Shen Liang |
12 Potential of vitamin C in the prevention and treatment of gout 期刊论文 Ji Hong-Fang |Shen Liang |
13 生物氧化还原反应的计算生物学与计算化学研究 奖励 张红雨|孔德信|纪洪芳|马斌广|申亮|陈玲玲|
14 Interactions of urocanic acid with bovine serum albumin and the influence of pH on binding affinities: a docking simulation study 期刊论文 Shen Liang |Ji Hong-Fang |
15 Small cofactors may assist protein emergence from RNA world: clues from RNA-protein complexes 期刊论文 Shen Liang |Ji Hong-Fang |
16 Triplet excited state characters and photosensitization mechanisms of alpha-terthienyl: A theoretical study 期刊论文 Hong-Fang Ji|Liang Shen|
17 Interactions of curcumin with the PfATP6 model and the implications for its antimalarial mechanism 期刊论文 Shen Liang |Ji Hong-Fang |
18 Photosensitization mechanisms of triplet excited state β-lapachone. A density functional theory study 期刊论文 Shen Liang |
19 Insights into the Disappointing Clinical Trials of Antioxidants in Neurodegenerative Diseases 期刊论文 Shen Liang |Ji Hong-Fang |
20 Mutation directional selection sheds light on prion pathogenesis 期刊论文 Ji Hong-Fang |Shen Liang |
21 Mechanisms of reactive oxygen species photogeneration by benzo[a]pyrene: A DFT study 期刊论文 Hong-Fang Ji|Liang Shen|
22 生物活性天然产物的作用机理研究 奖励 纪洪芳|申亮|
23 Insights into the inhibition of xanthine oxidase by curcumin 期刊论文 Ji Hong-Fang |Shen Liang |
24 The mechanisms of ROS-photogeneration by berberine, a natural isoquinoline alkaloid 期刊论文 Shen Liang |Ji Hong-Fang |
25 Impact of aspartate racemization on the conformational stability of Abeta(1–42) 期刊论文 Shen Liang |Ji Hong-Fang |
26 Comparative study on the conformational stability of human and murine amyloid β peptide 期刊论文 Shen Liang |Ji Hong-Fang |
27 Molecular basis for cis-urocanic acid as a 5-HT2A receptor agonist 期刊论文 Shen Liang |Ji Hong-Fang |
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