肝源因子Betatrophin重设肝脏生物时钟的分子机制研究

31771298
2017
C1106.衰老与生物节律
刘畅
面上项目
教授
中国药科大学
60万元
外周生物钟;授时因子;食物信号;牵引;肝脏
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Green light exposure aggravates high-fat diet feeding-induced hepatic steatosis and pancreatic dysfunction in male mice 期刊论文 Zhang Shiyao;Xu Mengyi;Shen Ziyue;Shang Changrui;Zhang Wenxiang;Chen Siyu;Liu Chang
2 Chronic exposure to green light aggravates high-fat diet-induced obesity and metabolic disorders in male mice 期刊论文 Zhang Shiyao;Zhang Yanchen;Zhang Wenxiang;Chen Siyu;Liu Chang
3 Self-assembled polymeric nanocarrier-mediated co-delivery of metformin and doxorubicin for melanoma therapy 期刊论文 Song Mingming;Xia Wentao;Tao Zixuan;Zhu Bin;Zhang Wenxiang;Liu Chang;Chen Siyu
4 脂肪组织靶向肽P3-壳聚糖寡聚乳酸-聚乙二醇递送系统及其在核酸药物递送上的应用 专利 陈思禹;刘畅;孙琛;宋明明;徐梦怡;张雯翔
5 脂肪组织中自噬信号通路及其功能 期刊论文 刘爽;孙琛;刘畅
6 Analysis of differentially expressed genes that aggravate metabolic diseases in depression 期刊论文 Bhadra Sukanta;Chen Siyu;Liu Chang
7 Bromide alleviates fatty acid-induced lipid accumulation in mouse primary hepatocytes through the activation of PPAR alpha signals 期刊论文 Shi Yujie;Zhang Wenxiang;Cheng Yinlong;Liu Chang;Chen Siyu
8 PPARs-orchestrated metabolic homeostasis in the adipose tissue 期刊论文 Sun Chen;Mao Shuyu;Chen Siyu;Zhang Wenxiang;Liu Chang
9 Chronopharmacology of simvastatin on hyperlipidaemia in high-fat diet-fed obese mice 期刊论文 Li Huan;Rabearivony Anjara;Zhang Wenxiang;Chen Siyu;An Xiaofei;Liu Chang
10 哺乳动物生物钟与肠道菌群关系的研究进展 期刊论文 熊勇红;邹怡欣;时雨杰;张雯翔;陈思禹;刘畅
11 靶向生物钟的小分子化合物的筛选与疾病治疗 期刊论文 焦雄;孙琛;刘畅
12 Genipin alleviates high-fat diet-induced hyperlipidemia and hepatic lipid accumulation in mice via miR-142a-5p/SREBP-1c axis 期刊论文 Zhong Hong;Chen Ke;Feng Mengyang;Shao Wei;Wu Jun;Chen Kun;Liang Tingming;Liu Chang
13 Cloxiquine, a traditional antituberculosis agent, suppresses the growth and metastasis of melanoma cells through activation of PPAR gamma 期刊论文 Zhang Wenxiang;Shao Wei;Dong Zhewen;Zhang Shiyao;Liu Chang;Chen Siyu
14 The long non-coding RNA Gm10768 activates hepatic gluconeogenesis by sequestering microRNA-214 in mice 期刊论文 Cui Xianwei;Tan Jingmin;Shi Yujie;Sun Chen;Li Yun;Ji Chenbo;Wu Jun;Zhang Zhao;Chen Siyu;Guo Xirong;Liu Chang
15 Integration of peripheral circadian clock and energy metabolism in metabolic tissues 期刊论文 Zhang Yanchen;Zhang Wenxiang;Liu Chang
16 Systemic Nanoparticle-Mediated Delivery of Pantetheinase Vanin-1 Regulates Lipolysis and Adiposity in Abdominal White Adipose Tissue 期刊论文 Chen Siyu;Zhang Wenxiang;Sun Chen;Song Mingming;Liu Shuang;Xu Mengyi;Zhang Xiaojin;Liu Li;Liu Chang
17 Silibinin A decreases statin-induced PCSK9 expression in human hepatoblastoma HepG2 cells 期刊论文 Dong Zhewen;Zhang Wenxiang;Chen Siyu;Liu Chang
18 Housing temperature affects the circadian rhythm of hepatic metabolism and clock genes 期刊论文 Anjara Rabearivony;Huan Li;Zhang Shiyao;Siyu Chen;Xiaofei An;Liu Chang
19 Angptl8 mediates food-driven resetting of hepatic circadian clock in mice 期刊论文 Chen Siyu;Feng Mengyang;Zhang Shiyao;Dong Zhewen;Wang Yifan;Zhang Wenxiang;Liu Chang
20 Endogenous circadian time genes expressions in the liver of mice under constant darkness 期刊论文 Huan Li;Shiyao Zhang;Wenxiang Zhang;Siyu Chen;Anjara Rabearivony;Yujie Shi;Jie Liu;Christopher J. Corton;Chang Liu
21 SWI/SNF complex subunit BAF60a represses hepatic ureagenesis through a crosstalk between YB-1 and PGC-1α 期刊论文 Zhang Wenxiang;Dong Zhewen;Xu Mengyi;Zhang Shiyao;Liu Chang;Chen Siyu
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