四株云南特色中药内生菌中治疗阿尔茨海默病的新型多靶向乙酰胆碱酯酶抑制剂的发现

81560571
2015
H3403.微生物药物
杨雪琼
地区科学基金项目
副教授
云南大学
35万元
生物转化;乙酰胆碱酯酶抑制剂;活性成分;植物内生菌;多靶点药物
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 New Azaphilones from Nigrospora oryzae Co-cultured with Beauveria bassiana 期刊论文 张倬熙;杨雪琼;周清艳;王邦艳;胡明;杨亚滨;周皓;丁中涛
2 New bioactive compounds from aquatic endophyte Chaetomium globosum 期刊论文 阮宝慧;余泽芬;杨雪琼;杨亚滨;胡明;张倬熙;周清艳;周皓;丁中涛
3 Inducing secondary metabolite production from Daldinia eschscholzii JC-15 by red ginseng medium 期刊论文 Wang Bang Yan;Yang Ya Bin;Yang Xue Qiong;Zhu Chen Hao;Yang Shuang;Xu Ting Ting;Wang Xue Yin;Tan Ning Hua;Zhou Hao;Ding Zhong Tao
4 Potential Antihyperlipidemic Polyketones from Endophytic Diaporthe sp. JC-J7 in Dendrobium nobile 期刊论文 胡明;杨雪琼;万春平;王邦艳;殷海月;史丽娇;吴娅梅;杨亚滨;周皓;丁中涛
5 Secondary Metabolites of the Fungus Aspergillus terreus 期刊论文 Chen Guang Yi;Ruan Bao Hui;Yang Ya Bin;Wang Qiang;Li Xiao Zhan;Luo Na;Yang Xue Qiong;Zhao Li Xing
6 Neopeapyran, an unusual furo[2,3b]pyran analogue and turnagainolide C from a soil Streptomyces sp. S2236 期刊论文 周皓;杨亚滨;段荣婷;杨雪琼;张举成;谢小光;赵立兴;丁中涛
7 Metabolites from Penicillium sp. associated with Paris polyphylla 期刊论文 李小战;阮宝慧;杨亚滨;杨雪琼;陈光奕;胡明;王邦燕;周皓;丁中涛
8 Benzopyran derivatives from endophytic Daldinia eschscholzii JC-15 in Dendrobium chrysotoxum and their bioactivities 期刊论文 Hu Ming;Yang Xue Qiong;Zhou Qing Yan;Li Shu Quan;Wang Bang Yan;Ruan Bao Hui;Yang Ya Bin;Zhang Zhuo Xi;Zhou Hao;Ding Zhong Tao
9 Lovastatin analogues and other metabolites from soil-derived Aspergillus terreus YIM PH30711 期刊论文 王强;杨亚滨;杨雪琼;苗翠萍;李一青;刘世熙;罗娜;丁中涛;赵立兴
10 Novel isochroman dimers from Stachybotrys sp. PH30583: Fermentation, isolation, structural elucidation and biological activities 期刊论文 黎唯;杨亚滨;杨雪琼;谢会定;邵志会;周皓;苗翠萍;赵立兴;丁中涛
11 A Novel Steroid Derivative and A New Steroidal Saponin from Endophytic Fungus Xylaria sp. 期刊论文 Li Wei;Yang Xue Qiong;Yang Ya Bin;Zhao Li Xing;Zhou Qing Yan;Zhang Zhuo Xi;Zhou Hao;Hu Ming;Ruan Bao Hui;Ding Zhong Tao
12 The streptazolin- and obscurolide-type metabolites from soil-derived Streptomyces alboniger YIM20533 and the mechanism of influence of g-butyrolactone on the growth of Streptomyces by their non-enzymatic reaction biosynthesis 期刊论文 杨雪琼
13 Acyclic isoprenoids of endophytic Aspergillus sp. Y-12 from Panax notoginseng 期刊论文 李琪玲;杨雪琼;杨亚滨;赵立兴;陈光奕;李小战;胡明;王邦燕;阮宝慧;周皓;丁中涛
14 8′-epimer of herbicidin F and its congeners from Streptomyces sp. YIM 66142 期刊论文 杨雪琼
15 New Bisabosquals from Stachybotrys sp. PH30583 Elicited on Solid Media 期刊论文 杨雪琼
16 Induction of Antiphytopathogenic Metabolite and Squalene Production and Phytotoxin Elimination by Adjustment of the Mode of Fermentation in Cocultures of Phytopathogenic Nigrospora oryzae and Irpex lacteus 期刊论文 Wu Ya Mei;Zhou Qing Yan;Yang Xue Qiong;Luo Yu Jie;Ojan Jing Jing;Liu Shi Xi;Yang Ya Bin;Ding Zhong Tao
17 New Natural Products of Rare Actinomycetes from 2006 to 2018 期刊论文 Zhang Jucheng;Yang Xueqiong;Zhou Hao;Yang Yabin;Ding Zhongtao
18 A NEW ISOCHROMAN DERIVATIVE FROM THE ENDOPHYTIC Microsphaeropsis arundinis 期刊论文 丁中涛
19 New Azaphilones and Tremulane Sesquiterpene from Endophytic Nigrospora oryzae Cocultured with Irpex lacteus 期刊论文 周清艳;杨雪琼;张倬熙;王邦艳;胡明;杨亚滨;周皓;丁中涛
20 Biotransformation of natural polyacetylene in red ginseng by Chaetomium globosum 期刊论文 杨雪琼
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