HO-1基因调控对MDS甲基化的影响及机制研究

81470006
2014
H0807.骨髓增生异常综合征
王季石
面上项目
教授
贵州医科大学
30万元
MDS;甲基化;HO-1;发病机制;骨髓增生异常综合征/;表观遗传学
2015-01-01到2016-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Induction of Heme Oxygenase-1 by Na-H Exchanger 1 Protein Plays a Crucial Role in Imatinib-resistant Chronic Myeloid Leukemia Cells 期刊论文 Xiuying Hu|Xiuying Hu|Jishi Wang|Jishi Wang|
2 Overexpression of heme oxygenase-1induced by constitutively activated NF-κB as a potential therapeutic target foractivated B-cell-like diffuse large B-cell lymphoma. 期刊论文 Fang Q|Fang Q|Wang J|Wang J|
3 Induction of Heme Oxygenase-1 by Na-H Exchanger 1 Protein Plays a Crucial Role in Imatinib-resistant Chronic Myeloid Leukemia Cells 期刊论文 Xiuying Hu|Xiuying Hu|Jishi Wang|Jishi Wang|
4 INPP4B-mediated DNA repair pathwayconfers resistance to chemotherapy in acute myeloid leukemia. 期刊论文 王季石|王季石|
5 INPP4B-mediated DNA repair pathwayconfers resistance to chemotherapy in acute myeloid leukemia. 期刊论文 王季石|王季石|
6 Potential crosstalk of theinterleukin-6-heme oxygenase-1-dependent mechanism involved in resistance tolenalidomide in multiple myeloma cells. 期刊论文 Cao L|Cao L|Wang JS|Wang JS|
7 Targeting of Heme oxygenase-1attenuates the negative impact of Ikaros isoform 6 in adult BCR-ABL1-positiveB-ALL. 期刊论文 黄君|黄君|王季石|王季石|
8 Potential crosstalk of theinterleukin-6-heme oxygenase-1-dependent mechanism involved in resistance tolenalidomide in multiple myeloma cells. 期刊论文 Cao L|Cao L|Wang JS|Wang JS|
9 Heme oxygenase-1 contributes to imatinibresistance by promoting autophagy in chronic myeloid leukemia throughdisrupting the mTOR signaling pathway. 期刊论文 Wang P|Wang P|Fang Q|Fang Q|
10 Hemeoxygenase-1 suppresses the apoptosis of acute myeloid leukemia cells via theJNK/c-JUN signaling pathway. 期刊论文 Lin X|Fang Q|Zhang Y|Wang J|
11 Role of heme oxygenase-1 indemethylating effects on SKM-1 cells induced by decitabine. 期刊论文 P. Wang|J. Sun|J.S. Wang|Q. Fang|
12 Silencing HO-1 sensitizes SKM-1 cellsto apoptosis induced by low concentration 5-azacytidine through enhancing p16demethylation. 期刊论文 Wang J|Wang J|Fang Q|Fang Q|
13 Identificationof Heme Oxygenase-1 as a Novel Predictor of Hematopoietic Stem CellTransplantation Outcomes in Acute Leukemia. 期刊论文 Wu D|Wang J|Li Y|Ma D|
14 Targeting of Heme oxygenase-1attenuates the negative impact of Ikaros isoform 6 in adult BCR-ABL1-positiveB-ALL. 期刊论文 黄君|黄君|王季石|王季石|
15 Downregulation of HO-1 promotedapoptosis induced by decitabine via increasing p15INK4B promoter demethylationin myelodysplastic syndrome. 期刊论文 Q Fang|P Wang|R Gao|JS Wang|
16 Overexpression of heme oxygenase-1induced by constitutively activated NF-κB as a potential therapeutic target foractivated B-cell-like diffuse large B-cell lymphoma. 期刊论文 Fang Q|Fang Q|Wang J|Wang J|
17 Silencing HO-1 sensitizes SKM-1 cellsto apoptosis induced by low concentration 5-azacytidine through enhancing p16demethylation. 期刊论文 Wang J|Wang J|Fang Q|Fang Q|
18 Heme oxygenase-1 contributes to imatinibresistance by promoting autophagy in chronic myeloid leukemia throughdisrupting the mTOR signaling pathway. 期刊论文 Wang P|Wang P|Fang Q|Fang Q|
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