基于压力应激-肠道微生态-中枢神经炎症系统调节的开心散抗抑郁作用机制研究

81673720
2016
H3301.中西医结合基础理论
朱悦
面上项目
教授
南京中医药大学
62万元
压力应激;中枢神经炎症;肠道微生态;抑郁症;开心散
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Jia-Wei-Kai-Xin-San, an Herbal Medicine Formula, Ameliorates Cognitive Deficits via Modulating Metabolism of Beta Amyloid Protein and Neurotrophic Factors in Hippocampus of A beta(1-42 )Induced Cognitive Deficit Mice 期刊论文 Zhu Yue;Shi Yiwei;Cao Cheng;Han Zhenxiang;Liu Mengqiu;Qi Mingzhu;Huang Renjie;Zhu Ziqiang;Qian Dawei;Duan Jin-Ao
2 Active components, derived from Kai-xin-san, a herbal formula, increase the expressions of neurotrophic factor NGF and BDNF on mouse astrocyte primary cultures via cAMP-dependent signaling pathway 期刊论文 Cao Cheng;Xiao Junyuan;Liu Mengqiu;Ge Zishuo;Huang Renjie;Qi Mingzhu;Zhu Hongliang;Zhu Yue;Duan Jin ao
3 具有抗抑郁与抗老年痴呆症功效的组合物及其应用 专利 朱悦;段金廒;詹华强
4 Kai-Xin-San series formulae alleviate depressive-like behaviors on chronic mild stressed mice via regulating neurotrophic factor system on hippocampus 期刊论文 Zhu Yue;Chao Cheng;Duan Xiuzhu;Cheng Xiaoxuan;Liu Pei;Su Shulan;Duan Jinao;Dong Tina Tingxia;Tsim Karl Wah-Keung
5 中药复方开心散调控慢性压力应激小鼠海马炎性细胞因子水平抗抑郁作用机制研究 期刊论文 曲苏晨;曹程;戚明珠;刘梦秋;段金廒;朱悦
6 Chinese medicine formula Kai-Xin-San ameliorates depression-like behaviours in chronic unpredictable mild stressed mice by regulating gut microbiota-inflammation-stress system 期刊论文 Cheng Cao;Mengqiu Liu;Suchen Qu;Renjie Huang;Mingzhu Qi;Ziqiang Zhu;Jiani Zheng;Zhichun Chen;Zhikang Wang;Zhengxiang Han;Yue Zhu;Fei Huang;Jin-ao Duan
7 中药复方开心散调控神经营养因子抗抑郁物质基础与作用机制研究 期刊论文 曹程;肖钧元;刘梦秋;黄人杰;戚明珠;朱梓强;王之康;陈铚淳;郑嘉妮;刘培;段金廒;朱悦
8 Comparative pharmacokinetic study of the components of Jia-Wei-Kai-Xin-San in normal and vascular dementia rats by ultra-fast liquid chromatography coupled with tandem mass spectrometry 期刊论文 Shi Yiwei;Cao Cheng;Zhu Yue;Gao Ting;Yang Wen;Liu Mengqiu;Qi Mingzhu;Huang Renjie;Qian Dawei;Duan Jin Ao
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