LAG-3调控HLA-DR基因参与帕金森病DA神经元变性的分子机制研究
81870992
2018
H0912.神经退行性变及相关疾病
徐评议
面上项目
教授
广州医科大学
56万元
基因突变;神经免疫紊乱;淋巴细胞活化基因-3;人白细胞抗原;帕金森病
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Functional validation of a human GLUD2 variant in a murine model of Parkinson's disease | 期刊论文 | Zhang Wenlong;Gong Junwei;Ding Liuyan;Zhang Zhiling;Pan Xiaowen;Chen Xiang;Guo Wenyuan;Zhang Xiaokang;Yang Xinling;Peng Guoyou;Lin Yuwan;Gao Feng;Li Yuanquan;Zhu Xiaoqin;Xuan Aiguo;Wang Shu;Sun Xiangdong;Zhang Yunlong;Xu Pingyi |
| 2 | Berberine Protects Against NLRP3 Inflammasome via Ameliorating Autophagic Impairment in MPTP-Induced Parkinson's Disease Model | 期刊论文 | Huang Shuxuan;Liu Hanqun;Lin Yuwan;Liu Muchang;Li Yanhua;Mao Hengxu;Zhang Zhiling;Zhang Yunlong;Ye Panghai;Ding Liuyan;Zhu Ziting;Yang Xinling;Chen Chaojun;Zhu Xiaoqin;Huang Xiaoyun;Guo Wenyuan;Xu Pingyi;Lu Lin |
| 3 | Gut bacterial profiles in Parkinson's disease: A systematic review | 期刊论文 | Zhe Li;Hongfeng Liang;Yingyu Hu;Lin Lu;Chunye Zheng;Yuzhen Fan;Bin Wu;Tao Zou;Xiaodong Luo;Xinchun Zhang;Yan Zeng;Ziyan Liu;Zhicheng Zhou;Zhenyu Yue;Yi Ren;Zhuo Li;Qiaozhen Su;Pingyi Xu |
| 4 | Analysis of Cerebrospinal Fluid Soluble TREM2 and Polymorphisms in Sporadic Parkinson’s Disease in a Chinese Population | 期刊论文 | Guoyou Peng;Jiewen Qiu;Hanqun Liu;Miaomiao Zhou;Shuxuan Huang;Wenyuan Guo;Yuwan Lin;Xiang Chen;Zhe Li;Guihua Li;Wenlong Zhang;Yunlong Zhang;Li Xingjian;Zhuohua Wu;Lei Wei;Xinling Yang;Xiaoqin Zhu;Mingshu Mo;Pingyi Xu |
| 5 | Genetic analysis of NUS1 in Chinese patients with Parkinson's disease. | 期刊论文 | Chen Xiang;Xiao Yousheng;Zhou Miaomiao;Lin Yuwan;Guo Wenyuan;Huang Shuxuan;Qiu Jiewen;Peng Guoyou;Mo Mingshu;Li Zhe;Zhu Xiaoqin;Xu Pingyi |
| 6 | Reduced regional activity and functional connectivity within sensorimotor network in Parkinson's patients with restless legs syndrome | 期刊论文 | Li Zhe;Chen Jun;Lin Yuwan;Zhou Miaomiao;Cai Qiaodi;Li Xinchun;Wu Zhuohua;Chen Xinjie;Yang Xinling;Zhu Xiaoqin;Lu Jianjun;Zhang Li;Liu Bo;Luo Xiaodong;Xu Pingyi |
| 7 | Trojan Horse Delivery of 4,4′-Dimethoxychalcone for Parkinsonian Neuroprotection | 期刊论文 | Wenlong Zhang;Huaqing Chen;Liuyan Ding;Junwei Gong;Mengran Zhang;Wenyuan Guo;Pingyi Xu;Shiying Li;Yunlong Zhang |
| 8 | Regulatory Roles of Bone in Neurodegenerative Diseases. | 期刊论文 | Zhengran Yu;Zemin Ling;Lin Lu;Jin Zhao;Xiang Chen;Pingyi Xu;Xuenong Zou |
| 9 | Association of LAG3 Genetic Variation With an Increased Risk of PD in Chinese Female Population | 期刊论文 | WY Guo;MM Zhou;JW Qiu;YW Lin;X Chen;SX Huang;MS Mo;HQ Liu;GY Peng;XQ Zhu;PY Xu |
| 10 | Bone-Derived Factors as Potential Biomarkers for Parkinson's Disease | 期刊论文 | Lin Yuwan;Zhou Miaomiao;Dai Wei;Guo Wenyuan;Qiu Jiewen;Zhang Zhiling;Mo Mingshu;Ding Liuyan;Ye Panghai;Wu Yijuan;Zhu Xiaoqin;Wu Zhuohua;Xu Pingyi;Chen Xiang |
| 11 | CNTNAP4 deficiency in dopaminergic neurons initiates parkinsonian phenotypes | 期刊论文 | WL Zhang;MM Zhou;WY Lu;JW Gong;F Gao;YQ Li;XD Xu;YW Lin;XK Zhang;LY Ding;ZL Zhang;GH Li;X Chen;XD Sun;XQ Zhu;PY Xu;YL Zhang |
| 12 | Soluble Triggering Receptor Expressed on Myeloid Cells 2 From Cerebrospinal Fluid in Sleep Disorders Related to Parkinson's Disease | 期刊论文 | Mo Mingshu;Tang Yuting;Wei Lijian;Qiu Jiewen;Peng Guoyou;Lin Yuwan;Zhou Miaomiao;Dai Wei;Zhang Zhiling;Chen Xiang;Liu Hanqun;Ding Liuyan;Ye Panghai;Wu Yijuan;Zhu Xiaoqin;Wu Zhuohua;Guo Wenyuan;Xu Pingyi |
| 13 | Association of CLU gene polymorphism with Parkinson's disease in the Chinese Han population | 期刊论文 | Lin Yuwan;Lu Lin;Zhou Miaomiao;Liu HanQun;Ye Panghai;Zhang Wenlong;Qiu Jiewen;Zhang Zhiling;Yang Xinling;Ding Liuyan;Guo Wenyuan;Mo Mingshu;Zhu Xiaoqin;Zhang Xiaokang;Chen Xiang;Xu Pingyi |
| 14 | The outcome and burden of Chinese patients with neurodegenerative diseases: A 10-year clinical feature study | 期刊论文 | Gui-Hua Li;Peng Li;Lin Lu;Zhe Li;Ming-Shu Mo;Xiang Chen;Guo-You Peng;Wen-Yuan Guo;Yu-Wan Lin;Jie-Wen Qiu;Xin-Ling Yang;Xin-Tong Liu;Ping-Yi Xu |
| 15 | Association of ADAM10 gene variants with sporadic Parkinson's disease in Chinese Han population | 期刊论文 | Zhou Miaomiao;Lin Yuwan;Lu Lin;Zhang Zhiling;Guo Wenyuan;Peng Guoyou;Zhang Wenlong;Zhu Ziting;Wu Zhuohua;Mo Mingshu;Yang Xinling;Zhu Xiaoqin;Chen Chaojun;Chen Xiang;Xu Pingyi |
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