遗传易感基因STAT3通过抑制中性粒细胞影响胆道闭锁病程的机制研究
81771629
2017
H0421.新生儿相关疾病
夏慧敏
面上项目
主任医师
广州医科大学
55万元
STAT3;胆道闭锁;中性粒细胞;CXCL1
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 一种将胚胎肝内胆管上皮细胞诱导分化为含成熟胆管上皮细胞和胆管结构的细胞模型的方法 | 专利 | 张锐忠;林泽锋;陈虹交;童燕陆;付铭;王贺珍;陈严;夏慧敏 |
| 2 | 一种慢性肝硬化胆道闭锁动物模型的构建方法 | 专利 | 张锐忠;林泽锋;陈严;夏慧敏 |
| 3 | 一种采用偏振光显微镜观察胶原纤维的染色方法 | 专利 | 张锐忠;林泽锋;付铭;童燕陆;陈虹交;王贺珍;陈严;夏慧敏 |
| 4 | Evaluation and accurate diagnoses of pediatric diseases using artificial intelligence | 期刊论文 | Liang Huiying;Tsui Brian Y.;Ni Hao;Valentim Carolina C. S.;Baxter Sally L.;Liu Guangjian;Cai Wenjia;Kermany Daniel S.;Sun Xin;Chen Jiancong;He Liya;Zhu Jie;Tian Pin;Shao Hua;Zheng Lianghong;Hou Rui;Hewett Sierra;Li Gen;Liang Ping;Zang Xuan;Zhang Zhiqi;Pan Liyan;Cai Huimin;Ling Rujuan;Li Shuhua;Cui Yongwang;Tang Shusheng;Ye Hong;Huang Xiaoyan;He Waner;Liang Wenqing;Zhang Qing;Jiang Jianmin... |
| 5 | Epistatic Association of CD14 and NOTCH2 Genetic Polymorphisms with Biliary Atresia in a Southern Chinese Population | 期刊论文 | Lin Zefeng;Xie Xiaoli;Lin Huiting;Fu Ming;Su Liang;Tong Yanlu;Chen Hongjiao;Wang Hezhen;Zhao Jinglu;Xia Huimin;Zhang Yan;Zhang Ruizhong |
| 6 | Liver Immune Profiling Reveals Pathogenesis and Therapeutics for Biliary Atresia. | 期刊论文 | Jun Wang;Yanhui Xu;Zhanghua Chen;Jiankun Liang;Zefeng Lin;Huiying Lian;Yiping Xu;Qi Wu;Xuanjie Guo;Junli Nie;Bingtai Lu;Bing Huang;Qiang Wu;Jixiao Zeng;Chengwei Chai;Meixue Zhang;Yuzhen Lin;Li Zhang;Shanmeizi Zhao;Yanlu Tong;Xiaoqiong Gu;Zhuang-gui Chen;Shuhong Yi;Tong Zhang;David Delfouneso;Yan Zhang;Stephen L Nutt;Andrew M Lew;Liwei Lu;Fan Bai... |
| 7 | The intragenic epistatic association of ADD3 with biliary atresia in Southern Han Chinese population | 期刊论文 | Wang Zhe;Xie Xiaoli;Zhao Jinglu;Fu Ming;Li Yonglan;Zhong Wei;Xia Huimin;Zhang Yan;Zhang Rui-Zhong |
| 8 | Association of IL18 genetic polymorphisms with increased risk of Biliary atresia susceptibility in Southern Chinese children | 期刊论文 | Liang Jiankun;Wen Zhe;Zhao Jinglu;Liang Qifeng;Liu Tao;Xia Huimin;Zhang Yan;Zhang RuiZhong |
| 9 | Beta-amyloid deposition around hepatic bile ducts is a novel pathobiological and diagnostic feature of biliary atresia | 期刊论文 | Babu Rosana Ottakandathil;Lui Vincent Chi Hang;Chen Yan;Yiu Rachel Sze Wan;Ye Yongqin;Niu Ben;Wu Zhongluan;Zhang Ruizhong;Yu Michelle On Na;Chung Patrick Ho Yu;Wong Kenneth Kak Yuen;Xia Huimin;Zhang Michael Qi;Wang Bin;Lendahl Urban;Tam Paul Kwong Hang |
| 10 | MDSCs在构建BA动物模型中的应用和BA小鼠模型的构建方法 | 专利 | 林泽锋;张锐忠;陈严;付铭;王哲;林辉婷;童燕陆;钟微;余家康;夏慧敏 |
| 11 | Down-regulation of STAT3 enhanced chemokine expression and neutrophil recruitment in biliary atresia | 期刊论文 | 夏慧敏 |
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