交通尾气颗粒物致健康损害效应的关键组分及人群生物标志物研究
91643203
2016
H3001.环境卫生
郑玉新
重大研究计划
教授
青岛大学
296万元
大气颗粒物;交通污染;生物标志物;毒性效应;分子流行病学
2017-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 炭黑对人支气管上皮细胞细胞器功能和凋亡的影响及机制 | 期刊论文 | 王广雷;郑小美;郑玉新 |
| 2 | FLT1 hypermethylation is involved in polycyclic aromatic hydrocarbons-induced cell transformation | 期刊论文 | Zhini He;Rui Zhang;Shen Chen;Liping Chen;Huiyao Li;Lizhu Ye;Qiong Li;Ziwei Wang;Qing Wang;Huawei Duan;Yong Niu;Yongmei Xiao;Guanghui Dong;Daochuan Li;Dianke Yu;Yuxin Zheng;Xiumei Xing;Wen Chen |
| 3 | Ambient air pollutants and hospital visits for pneumonia: a case-crossover study in Qingdao, China | 期刊论文 | Jianzhong Zhang;Dunqiang Ren;Xue Cao;Tao Wang;Xue Geng;Xin Li;Jinglong Tang;Shuguang Leng;Hongmei Wang;Yuxin Zheng |
| 4 | 高分辨率CT重建气道参数及一般人群参考值范围 | 期刊论文 | 曹雪;林立;李燕婷;刘红;刘元升;唐敬龙;韩伟;冷曙光;余善法;郑玉新 |
| 5 | Time-course effects of antioxidants and phase II enzymes on diesel exhaust particles-induced oxidative damage in the mouse lung | 期刊论文 | Xiaomei Zheng;Guanglei Wang;Ping Bin;Tao Meng;Yong Niu;Mo Yang;Liping Zhang;Huawei Duan;Tao Yu;Yufei Dai;Yuxin Zheng |
| 6 | In ovo very early-in-life exposure to diesel exhaust induced cardiopulmonary toxicity in a hatchling chick model | 期刊论文 | Qixiao Jiang;Xiaohui Xu;Chao Zhang;Jing Luo;Na Lv;Limei Shi;Andong Ji;Mengyu Gao;Feilong Chen;Lianhua Cui;Yuxin Zheng |
| 7 | 一种组织液的制备方法 | 专利 | 唐敬龙;郑玉新;李燕婷 |
| 8 | 一种鸡胚柴油机尾气染毒方法 | 专利 | 姜启晓;郑玉新 |
| 9 | Association between Atmospheric Particulate Pollutants and Mortality for Cardio-Cerebrovascular Diseases in Chinese Korean Population: A Case-Crossover Study | 期刊论文 | Chao Zhang;Zhenyu Quan;Qincheng Wu;Zhezhen Jin;Joseph Lee;Chunhua Li;Yuxin Zheng;Lianhua Cui |
| 10 | Real-ambient exposure to air pollution exaggerates excessive growth of adipose tissue modulated by Nrf2 signal | 期刊论文 | Menghui Jiang;Daochuan Li;Jinmei Piao;Jianyu Li;Hao Sun;Liping Chen;Shen Chen;Jingbo Pi;Rong Zhang;Rui Chen;Shuguang Leng;Wen Chen;Yuxin Zheng |
| 11 | WHO人造纳米材料职业防护指南解读 | 期刊论文 | 唐敬龙;郑玉新 |
| 12 | Association between coronavirus disease 2019 (COVID-19) and long-term exposure to air pollution: Evidence from the first epidemic wave in China | 期刊论文 | Pai Zheng;Zhangjian Chen;Yonghong Liu;Hongbin Song;Chieh-Hsi Wu;Bingying Li;Moritz U.G. Kraemer;Huaiyu Tian;Xing Yan;Yuxin Zheng;Nils Chr. Stenseth;Guang Jia |
| 13 | High-content analysis of particulate matters-induced oxidative stress and organelle dysfunction in vitro | 期刊论文 | Guanglei Wang;Xiaomei Zheng;Huawei Duan;Yufei Dai;Yong Niu;Jinling Gao;Zhishang Chang;Xuxia Song;Shuguang Leng;Jinglong Tang;Yuxin Zheng |
| 14 | Occupational exposure to carbon black nanoparticles increases inflammatory vascular disease risk: an implication of an ex vivo biosensor assay | 期刊论文 | Jinglong Tang;Wenting Cheng;Jinling Gao;Yanting Li;Ruyong Yao;Nathaniel Rothman;Qing Lan;Matthew J. Campen;Yuxin Zheng;Shuguang Leng |
| 15 | TGFb/Smad mediated the polyhexamethyleneguanide areosol-induced irreversible pulmonary fibrosis in subchronic inhalation exposure | 期刊论文 | Xiaoxiao Zhu;Xiao Kong;Sai Ma;Rui Liu;Xin Li;Shaobo Gao;Dunqiang Ren;Yuxin Zheng;Jinglong Tang |
| 16 | 一种禽蛋气室闭式染毒系统 | 专利 | 姜启晓;郑玉新 |
| 17 | Reduced serum club cell protein as a pulmonary damage marker for chronic fine particulate matter exposure in Chinese population | 期刊论文 | Yanhua Wang;Huawei Duan;Tao Meng;Meili Shen;Qianpeng Ji;Jie Xing;Qingrong Wang;Ting Wang;Yong Niu;Tao Yu;Zhong Liu;Hongbing Jia;Yuliang Zhan;Wen Chen;Zhihu Zhang;Wenge Su;Yufei Dai;Xuchun Zhang;Yuxin Zheng |
| 18 | Suppression of PTPN6 exacerbates aluminum oxide nanoparticle-induced COPD-like lesions in mice through activation of STAT pathway | 期刊论文 | Xiaobo Li;Hongbao Yang;Shenshen Wu;Qingtao Meng;Hao Sun;Runze Lu;Jian Cui;Yuxin Zheng;Wen Chen;Rong Zhang;Michael Aschner;Rui Chen |
| 19 | PM_(2.5)气室注射染毒对鸡胚肝脏发育的毒性效应 | 期刊论文 | 石李梅;陈飞龙;张超;赵恩慧;马媛媛;李道传;姜启晓;郑玉新;崔莲花 |
| 20 | Particulate Matter 2.5 Induced Developmental Cardiotoxicity in Chicken Embryo and Hatchling | 期刊论文 | Qixiao Jiang;Chao Zhang;Shen Chen;Limei Shi;Dao Chuan Li;Na Lv;Lianhua Cui;Yanxia Chen;Yuxin Zheng |
| 21 | The development of a cell-based model for the assessment of carcinogenic potential upon long-term PM2.5 exposure | 期刊论文 | Shen Chen;Daochuan Li;Haiyan Zhang;Dianke Yu;Rui Chen;Bin Zhang;Yafei Tan;Yong Niu;Huawei Duan;Bixian Mai;Shejun Chen;Jianzhen Yu;Tiangang Luan;Liping Chen;Xiumei Xing;Qiong Li;Yongmei Xiao;Guanghui Dong;Yujie Niu;Michael Aschner;Rong Zhang;Yuxin Zheng;Wen Chen |
| 22 | 一种体外呼吸暴露模型构建方法和应用 | 专利 | 唐敬龙;王红梅;程文婷;尹慧敏 |
| 23 | Association between air pollution and lung development in schoolchildren in China | 期刊论文 | Tao Wang;Haitao Wang;Jian Chen;Jiansheng Wang;Dunqiang Ren;Wei Hu;Hongmei Wang;Wei Han;Shuguang Leng;Rong Zhang;Yuxin Zheng |
| 24 | The Role of Nrf2 in the PM-Induced Vascular Injury Under Real Ambient Particulate Matter Exposure in C57/B6 Mice | 期刊论文 | Mengyu Gao;Ma Yuanyuan;Jing Luo;Daochuan Li;Menghui Jiang;Qixiao Jiang;Jingbo Pi;Rui Chen;Wen Chen;Rong Zhang;Yuxin Zheng;Lianhua Cui |
| 25 | 中国2018年PM_(2.5)的空间分布特征——基于地理信息系统的研究 | 期刊论文 | 王涛;王明悦;胡薇;周云平;郑玉新;冷曙光 |
| 26 | 吸入胍类消毒剂致肺损伤的毒性特征及机制研究进展 | 期刊论文 | 唐敬龙;祝肖肖;郑玉新 |
| 27 | Small airway wall thickening assessed by computerized tomography is associated with low lung function in Chinese carbon black packers | 期刊论文 | Xue Cao;Li Lin;Akshay Sood;Qianli Ma;Xiangyun Zhang;Yuansheng Liu;Hong Liu;Yanting Li;Tao Wang;Jinglong Tang;Menghui Jiang;Rong Zhang;hanfa Yu;ZhiqiangYu;Yuxin Zheng;Wei Han;Shuguang Leng |
| 28 | 青岛市大气污染物对心脑血管疾病住院影响的 病例交叉研究 | 期刊论文 | 吴钦城;郑玉新;朴金梅;蒋梦会;崔莲花 |
| 29 | Local and Systemic Inflammation May Mediate Diesel Engine Exhaust-Induced Lung Function Impairment in a Chinese Occupational Cohort | 期刊论文 | Haitao Wang;Huawei Duan;Tao Meng;Mo Yang;Lianhua Cui;Ping Bin;Yufei Dai;Yong Niu;Meilin Shen;Liping Zhang;Yuxin Zheng;Shuguang Leng |
| 30 | Multiple organ injury in male C57BL/6J mice exposed to ambient particulate matter in a real-ambient PM exposure system in Shijiazhuang, China | 期刊论文 | Daochuan Li;Rong Zhang;Lianhua Cui;Chen Chu;Haiyan Zhang;Hao Sun;Jing Luo;Lixiao Zhou;Liping Chen;Jian Cui;Shen Chen;Bixian Mai;Shejun Chen;Jianzhen Yu;Zongwei Cai;Jianqing Zhang;Yousheng Jiang;Michael Aschner;Rui Chen;Yuxin Zheng;Wen Chen |
| 31 | LIN28B/let-7 axis mediates pulmonary inflammatory response induced by diesel exhaust particle exposure in mice | 期刊论文 | Guanglei Wang;Xiaomei Zheng;Jinglong Tang;Yong Niu;Yufei Dai;Huawei Duan;Yuxin Zheng |
| 32 | Carbon content in airway macrophages and genomic instability in Chinese carbon black packers | 期刊论文 | Wenting Cheng;Yuansheng Liu;Jinglong Tang;Huawei Duan;Xiaoran Wei;Xiao Zhang;Shanfa Yu;Matthew J. Campen;Wei Han;Nathaniel Rothman;Steven A. Belinsky;Qing Lan;Yuxin Zheng |
| 33 | 诱导痰中巨噬细胞碳含量的定量方法 | 期刊论文 | 刘元升;李建宇;管鸽;曹雪;蒋梦会;祝肖肖;魏禄堂;冷曙光;郑玉新 |
| 34 | 一种肺纤维化哺乳动物模型的构建及应用 | 专利 | 唐敬龙;郑玉新;祝肖肖 |
| 35 | Exposure characterization and estimation of benchmark dose for cancer biomarkers in an occupational cohort of diesel engine testers | 期刊论文 | Yong Niu;Xiao Zhang;Tao Meng;Haisheng Wang;Ping Bin;Meili Shen;Wen Chen;Shanfa Yu;Shuguang Leng;Yuxin Zheng |
| 36 | Cardiac dysfunction and metabolic remodeling due to seasonally ambient fifine particles exposure | 期刊论文 | Jingxu Zhang;Qunfang Zhou;Ruijun Su;Zhendong Sun;Weifang Zhang;Xiaoting Jin;Yuxin Zheng |
| 37 | Real-Ambient Particulate Matter Exposure-Induced Cardiotoxicity in C57/B6 Mice | 期刊论文 | Lianhua Cui;Limei Shi;Daochuan Li;Xiaobo Li;Xuan Su;Liping Chen;Qixiao Jiang;Menghui Jiang;Jing Luo;Andong Ji;Chen Chen;Jianxun Wang;JingLong Tang;Jingbo Pi;Rui Chen;Wen Chen;Rong Zhang;Yuxin Zheng |
| 38 | Oxidative stress induced by ultrafine carbon black particles can elicit apoptosis in vivo and vitro | 期刊论文 | Yanting Li;Mo Yang;Tao Meng;Yong Niu;Yufei Dai;Liping Zhang;Xiaomei Zheng;Pasi Jalava;Guanghui Dong;Weimin Gao;Yuxin Zheng |
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