谷氨酰胺酶GLS的琥珀酰化修饰及其在胰腺导管腺癌中的作用与机制研究
81902423
2019
H1807.肿瘤代谢
郭栋
青年科学基金项目
助理研究员
青岛大学
21万元
琥珀酰化;谷氨酰胺酶;胰腺外分泌肿瘤;琥珀酰辅酶A连接酶
2020-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | KAT2A succinyltransferase activity-mediated 14-3-3ζ upregulation promotes β-catenin stabilization-dependent glycolysis and proliferation of pancreatic carcinoma cells | 期刊论文 | Yingying Tong;Dong Guo;Dong Yan;Chunmin Ma;Fei Shao;Yugang Wang;Shudi Luo;Liming Lin;Jingjing Tao;Yuhui Jiang;Zhimin Lu;Dongming Xing |
| 2 | Aerobic glycolysis promotes tumor immune evasion by hexokinase 2-mediated phosphorylation of IκBα | 期刊论文 | Dong Guo;Yingying Tong;Xiaoming Jiang;Ying Meng;Hongfei Jiang;Linyong Du;Qingang Wu;Shan Li;Shudi Luo;Min Li;Liwei Xiao;Haiyan He;Xuxiao He;Qiujing Yu;Jing Fang;Zhimin Lu |
| 3 | SUCLA2-coupled regulation of GLS succinylation and activity counteracts oxidative stress in tumor cells | 期刊论文 | Yingying Tong;Dong Guo;Shu-Hai Lin;Liangjia Zhen;Dianqiang Yang;Chunmin Ma;Fei Shao;Min Li;Qiujing Yu;Yuhui Jiang;Lei Li;Jing Fang;Rilei Yu;Zhimin Lu |
| 4 | Hypoxia-induced NFATc3 deSUMOylation enhances pancreatic carcinoma progression | 期刊论文 | Yingying Tong;Zheng Zhang;Yurong Cheng;Jing Yang;Cong Fan;Xuyang Zhang;Jiandong Yang;Li Wang;Dong Guo;Dong Yan |
| 5 | Determiners of cell fates: the TCA cycle versus the citrate-malate shuttle | 期刊论文 | Dong Guo;Haiyan He;Ying Meng;Shudi Luo;Zhimin Lu |
| 6 | CEND1 deficiency induces mitochondrial dysfunction and cognitive impairment in Alzheimer's disease | 期刊论文 | Wenting Xie;Dong Guo;Jieyin Li;Lei Yue;Qi Kang;Guimiao Chen;Tingwen Zhou;Han Wang;Kai Zhuang;Lige Leng;Huifang Li;Zhenyi Chen;Weiwei Gao;Jie Zhang |
| 7 | Governing glutaminolysis by regulation of glutaminase succinylation | 期刊论文 | Qingxia Ma;Hongfei Jiang;Leina Ma;Ying Meng;Dong Guo;Yingying Tong;Zhimin Lu |
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