氯胍通过网格蛋白非依赖内吞促进EGFR泛素化降解抑制肌层浸润性膀胱癌生长的机制研究

81874212
2018
H1814.肿瘤化学药物治疗
杨小平
面上项目
教授
湖南师范大学
58万元
肌层浸润性膀胱癌;氯胍;表皮生长因子受体;内吞;泛素化
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
查看更多信息请先登录或注册
查看更多信息请先登录或注册
查看更多信息请先登录或注册
重置
序号 标题 类型 作者
1 Novel Application of Metformin Combined with Targeted Drugs on Anticancer Treatment 期刊论文 Jun Deng;Mei Peng;Zhiren Wang;Sichun Zhou;Di Xiao;Jiating Deng;Xue Yang;Jingyuan Peng;Xiaoping Yang
2 1-n-heptyl-5-(3, 4-difluorophenyl) biguanide inhibits non-small cell lung cancer cell growth by downregulating the EGFR signaling pathways 期刊论文 Xiao Di;Peng Mei;Deng Yang;Xiao Yayi;Chen Xinyi;Ma Lan;Tang Bei;Guo Chenglin;Yang Xiaoping
3 Inhibitory role of proguanil on the growth of bladder cancer via enhancing EGFR degradation and inhibiting its downstream signaling pathway to induce autophagy 期刊论文 Di Xiao;Xin Hu;Mei Peng;Jun Deng;Sichun Zhou;Simeng Xu;Jingtao Wu;Xiaoping Yang
4 Inhibition of PKM2 Enhances Sensitivity of Olaparib to Ovarian Cancer Cells and Induces DNA Damage 期刊论文 Sichun Zhou;Duo Li;Di Xiao;Tianyu Wu;Xin Hu;Yu Zhang;Jun Deng;Jing Long;Simeng Xu;Jingtao Wu;Gaofeng Li;Mei Peng;Xiaoping Yang
5 Synthesis, biological evaluation and anti-proliferative mechanism of fluorine-containing proguanil derivatives 期刊论文 Xiao Di;Lu Zhicheng;Wang Zhiren;Zhou Sichun;Cao Mengru;Deng Jun;Hu Xin;Peng Mei;He Caimei;Wu Jingtao;Xu Simeng;Zhang Huihui;Xu Cangcang;Wang Wei;Guan Aiying;Yang Xiaoping
6 Proguanil synergistically sensitizes ovarian cancer cells to olaparib by increasing DNA damage and inducing apoptosis 期刊论文 Yan Wu;Tianyu Wu;Xin Hu;Simeng Xu;Di Xiao;Jingtao Wu;Xinjian Yan;Xiaoping Yang;Gaofeng Li
7 一种双胍衍生物、药物组合物、制备方法和其在制备抗肿瘤药物中的应用 专利 杨小平;肖迪;王志仁;周思纯;邓俊;胡鑫;彭美;贺彩梅
8 Novel Combination Therapies for the Treatment of Bladder Cancer. 期刊论文 Mei Peng;Di Xiao;Yizhi Bu;Jiahui Long;Xue Yang;Shuhe Lv;Xiaoping Yang
9 Synthesis, Anticancer Activities, and Mechanism of N-Heptyl-Containing Biguanide Derivatives 期刊论文 Wei Wang;Di Xiao;Sichun Zhou;Simeng Xu;Xinyi Tang;Xinchong Zhou;Jinbing Liu;Cangcang Xu;Mei Peng;Xiaoping Yang
10 Synthesis, Anti-Proliferative Evaluation and Mechanism of 4-Trifluoro Methoxy Proguanil Derivatives with Various Carbon Chain Length 期刊论文 Simeng Xu;Yufang Cao;Yu Luo;Di Xiao;Wei Wang;Zhiren Wang;Xiaoping Yang
11 一种双胍衍生物、药物组合物、制备方法和用途 专利 杨小平;周思纯;徐思梦;王志仁;邓俊;贺彩梅;肖迪;胡鑫;吴景涛
12 氯胍在制备抗肿瘤药物中的应用 专利 杨小平;达科欧;唐弼熙;邓俊;贺彩梅;陶婷;黄妍君;苏琼丽;彭美
13 Metformin targets Clusterin to control lipogenesis and inhibit the growth of bladder cancer cells through SREBP-1c/FASN axis 期刊论文 Deng Jun;Peng Mei;Zhou Sichun;Xiao Di;Hu Xin;Xu Simeng;Wu Jingtao;Yang Xiaoping
14 Dual Inhibition of Pirarubicin-Induced AKT and ERK Activations by Phenformin Sensitively Suppresses Bladder Cancer Growth 期刊论文 Mei Peng;Jun Deng;Sichun Zhou;Di Xiao;Jiahui Long;Nan Zhang;Caimei He;Miao Mo;Xiaoping Yang
查看更多信息请先登录或注册

相关项目

趋势报告

经验分享