CD147调节的CatSper非依赖性钙离子内流对人精子功能的作用及机制研究
81871202
2018
H0405.精子发生异常与男性不育
陈浩
面上项目
教授
南通大学
56万元
CatSper;精子活力;精子功能;CD147蛋白;弱精子症
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Defb19 regulates the migration of germ cell and is involved in male fertility | 期刊论文 | Jing Jin;Xiaofeng Li;Mei Ye;Feng Qiao;Hao Chen;Kin Lam Fok |
| 2 | CD147 deficiency is associated with impairedsperm motility/acrosome reaction and offers a therapeutic target for asthenozoospermia. | 期刊论文 | Hao Chen;Xiao Shi;Xiaofeng Li;Ruiying Diao;Qian Ma;Jing Jin;Zhuolin Qiu;Cailing Li;Mei Kuen Yu;Chaoqun Wang;Xianxin Li;Fanghong Li;David Yiu Leung Chan;Allan Zijian Zhao;Zhiming Cai;Fei Sun;Kin Lam Fok |
| 3 | Expression of cellular apoptosis susceptibility (CAS) in the human testis and testicular germ cell tumors | 期刊论文 | Liu Jianni;Ye Mei;Han Ruigang;Gui Yaoting;Li Xiaofeng;Zhang Han;Wang Xin;Guo Haoran;Li Fanghong;Zhao Allan Zijian;Guan Kunping;Chen Hao |
| 4 | Cellular apoptosis susceptibility protein (CAS) suppresses the proliferation of breast cancer cells by upregulated cyp24a1 | 期刊论文 | Ye Mei;Han Ruigang;Shi Jianwu;Wang Xunda;Zhao Allan Z.;Li Fanghong;Chen Hao |
| 5 | The repertoire of testicular extracellular vesicle cargoes and their involvement in inter-compartmental communication associated with spermatogenesis | 期刊论文 | Kathleen Hoi Kei Choy;Sze Yan Chan;William Lam;Jing Jin;Tingting Zheng;Tin Yu Samuel Law;Sidney Siubun Yu;Weiping Wang;Linxian Li;Gangcai Xie;Howard Chi Ho Yim;Hao Chen;Ellis Kin Lam Fok |
| 6 | Epididymis cell atlas in a patient with a sex development disorder and a novel NR5A1 gene mutation | 期刊论文 | Jian-Wu Shi;Yi-Wen Zhou;Yu-Fei Chen;Mei Ye;Feng Qiao;Jia-Wei Tian;Meng-Ya Zhang;Hao-Cheng Lin;Gang-Cai Xie;Kin Lam Fok;Hui Jiang;Yang Liu;Hao Chen |
| 7 | Spatio-temporal landscape of mouse epididymal cells and specific mitochondria-rich segments defined by large-scale single-cell RNA-seq | 期刊论文 | Shi Jianwu;Fok Kin Lam;Dai Pengyuan;Qiao Feng;Zhang Mengya;Liu Huage;Sang Mengmeng;Ye Mei;Liu Yang;Zhou Yiwen;Wang Chengniu;Sun Fei;Xie Gangcai;Chen Hao |
| 8 | CSE1L / CAS regulates cell proliferation through CDK signalling in mouse spermatogenesis | 期刊论文 | Jianwu Shi;Feng Qiao;Mei Ye;Ting Jiang;Jianni Liu;Mengya Zhang;Gangcai Xie;Kin Lam Fok;Xiaofeng Li;Hao Chen |
| 9 | The N501Y Mutation of SARS-CoV-2 Spike Protein Impairs Spindle Assembly in Mouse Oocytes. | 期刊论文 | Liu Huage;Shi Jianwu;Fok Kin Lam;Chen Hao |
| 10 | β-Defensin 19/119 mediates sperm chemotaxis and is associated with idiopathic infertility | 期刊论文 | Xiaofeng Li;Chun Yuan;Jianwu Shi;Hang Kang;Yufei Chen;Yonggang Duan;Jing Jin;Lai Ping Cheung;Tin Chiu Li;Ying Liu;Yugui Cui;Ye Chun Ruan;Xiaohua Jiang;Zhiming Cai;Hsiao Chang Chan;Ling Ji;Xuhui Zeng;Jiaying Liu;Hao Chen;Kin Lam Fok |
| 11 | Interfering with CSE1L/CAS inhibits tumour growth via C3 in triple‐negative breast cancer | 期刊论文 | Mei Ye;Yufei Chen;Jianni Liu;Jiawei Tian;Xunda Wang;Kin Lam Fok;Jianwu Shi;Hao Chen |
| 12 | Impairment of spermatogenesis and sperm motility by the high-fat diet-induced dysbiosis of gut microbes | 期刊论文 | Ding Ning;Zhang Xin;Zhang Xue Di;Jing Jun;Liu Shan Shan;Mu Yun Ping;Peng Li Li;Yan Yun Jing;Xiao Geng Miao;Bi Xin Yun;Chen Hao;Li Fang Hong;Yao Bing;Zhao Allan Z |
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