【30971054】GSK-3β介导的海马损伤与抑郁症国家自然基金项目

GSK-3β介导的海马损伤与抑郁症

项目批准号： 30971054

批准年份： 2009

学科分类： H1007.心境障碍

项目负责人：张克让

资助类别：面上项目

负责人职称：教授

依托单位：山西医科大学

资助金额： 35万元

关键词：糖原合成酶激酶3β（glycogen;kinase-3β;海马损伤（hippocampal;神经影像（neuroimaging）;GSK-3β）;基因多态性（polymorphism）;synthase;抑郁症（depression）;lesion）

起止时间： 2010-01-01到2012-12-31

中英文摘要
结题摘要
结题报告
项目成果
项目参与人

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序号	标题	类型	作者
1	Genetic association of the interaction between the BDNF and GSK3B genes and major depressive disorder in a Chinese population	期刊论文	Kerang Zhang\|Chunxia Yang\|Yong Xu\|Ning Sun\|Qi Xu\|Yan Shen\|
2	A polymorphism in the microRNA-30e precursors associated with major depressive disorder risk and P300 waveform	期刊论文	Yong Xu,\|Haiying Liu\|Fei Li\|Ning Sun\|Yan Ren\|Zhifen Liu\|Pozi Liu\|Kerang Zhang\|
3	Genotypic Association of the DAOA Gene with Resting-State Brain Activity in Major Depression	期刊论文	Cheng Xu\|Kerang Zhang\|Yan Shen\|Qi Xu\|
4	基因工程鼠模型在抑郁障碍中的研究进展.	期刊论文	王磊\|张克让\|
5	脑源性神经营养因子基因多态性与西酞普兰临床疗效的关联性.	期刊论文	宋喜\|孙宁\|刘莎\|任燕\|杨春霞\|刘志芬\|曹晓华\|张克让\|
6	Decreased Regional Homogeneity in Insula and Cerebellum: an Resting-State fMRI Study in Patients with Major Depression and Subjects at High-Risk for Major Depression.	期刊论文	Zhifen Liu\|Cheng Xu\|Yong Xu\|Kerang Zhang\|Chongxi Du\|
7	AKT1基因多态性与重性抑郁障碍认知功能的关联分析	期刊论文	李剑虹\|王磊\|张克让\|徐勇\|孙宁\|彭菊意\|
8	Continuous GSK-3b overexpression in the hippocampal dentate gyrus induces prodepressant-like effects and increase essensitivity to chronic mild stress in mice.	期刊论文	Xin Zhao\|Zhifen Liu\|Zhongchen Xie\|Jvyi Peng\|
9	Effects of an antidepressant on neural correlates of emotional processing in patients with major depression .	期刊论文	Zhifen Liu\|Ning Sun\|Yan Ren\|Kerang Zhang\|
10	Possible Association of the GSK3b Genewith the Anxiety Symptoms of Major Depressive Disorder and P300 Waveform.	期刊论文	Yan Sun\|Qi Xu\|Kerang Zhang\|Yan Shen\|
11	Disrupted resting-state functional connectivity of the hippocampus in medication-naïve patients with major depressive disorder.	期刊论文	Xiaohua Cao\|Kerang Zhang\|Zhifen Liu\|Cheng Xu\|Jianying Li\|Qiang Gao\|Ning Sun\|Yong Xu\|Yan Ren\|Chunxia Yang\|
12	Association between AKT1 gene polymorphisms and depressive symptoms in the Chinese Han population with major depressive disorder.	期刊论文	Chunxia Yang\|Ning Sun\|Yan Ren\|Yan Sun\|Yong Xu\|Aiping Li\|Kewen Wu\|Kerang Zhang\|
13	抑郁障碍患者抑郁症状与人格、生活事件、应对方式和社会支持相关研究	期刊论文	李建英\|王彦芳\|彭菊意\|杨春霞\|宋喜\|李素萍\|张克让\|
14	The Combined Effects of the BDNF and GSK3B Genes Modulate the relationship between Negative life events and Major Depressive Disorder.	期刊论文	Yang Chunxia\|Xu Yong\|Sun Ning\|Ren Yan\|Liu Zhifen\|Cao Xiaohua\|Zhang Kerang\|
15	住院焦虑障碍患者的脑电超慢涨落图分析	期刊论文	王磊\|刘志芬\|段慧君\|任燕\|刘炜炜\|向玉仙\|李素萍\|张克让\|

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