基于靶酶－中空纤维离心超滤－液质联用技术的中药中酪氨酸酶抑制剂的筛选及活性评价研究

81603066
2016
H3410.药物分析
李德强
青年科学基金项目
副主任药师
河北医科大学
17万元
中药分析;酪氨酸酶抑制剂;活性评价;中药;亲和筛选
2017-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 中空纤维固定化酪氨酸酶法快速筛选北沙参中 抗黑色素生成活性成分 期刊论文 段坤峰;尹星烁;郑旭光;李德强
2 Furanodiene Induces Extrinsic and Intrinsic Apoptosis in Doxorubicin-Resistant MCF-7 Breast Cancer Cells via NF-kappa B-Independent Mechanism 期刊论文 Zhong Zhang Feng;Yu Hai Bing;Wang Chun Ming;Qiang Wen An;Wang Sheng Peng;Zhang Jin Ming;Yu Hua;Cui Liao;Wu Tie;Li De Qiang;Wang Yi Tao
3 Screening and identification of potential tyrosinase inhibitors from Semen Oroxyli extract by ultrafiltration LC-MS and in silico molecular docking 期刊论文 Xing-shuo Yin;Xue-qin Zhang;Jin-tuo Yin;De-zhi Kong;De-qiang Li
4 UPLC-MS/MS法测定积雪草中7种有效成分的含量 期刊论文 闫凯;徐艳梅;徐敬朴;段天玮;李德强
5 On-line immobilized trypsin microreactor for evaluating inhibitory activity of phenolic acids by capillary electrophoresis and molecular docking 期刊论文 Hao Zhang;Zhao-Yu Wu;Yin-Zhen Wang;Dong-Dong Zhou;Feng-qing Yang;De-qiang Li
6 色谱联用技术在中药酪氨酸酶抑制药筛选中的 研究现状 期刊论文 尹星烁;李国芳;李德强
7 Comprehensive Study of the in Vivo and in Vitro Metabolism of Dietary Isoflavone Biochanin A Based on UHPLC-Q-TOF-MS/MS 期刊论文 Jin-tuo Yin;Xiao-wei Zhang;Yu-qian Zhang;Yin-ling Ma;Lu-ya Li;De-qiang Li;Lan-tong Zhang;Zhi-qing Zhang
8 Structural characterization, antioxidant activity, and antiglycation activity of polysaccharides from different chrysanthemum teas 期刊论文 Qin Yuan;Yuan Fu;Pan-yin Xiang;Li Zhao;Sheng-peng Wang;Qing Zhang;Yun-tao Liu;Wen Qin;De-qiang Li;Ding-tao Wu
9 Capillary electrophoresis-based online immobilized enzyme reactor for beta-glucosidase kinetics assays and inhibitors screening 期刊论文 Wu Zhao Yu;Zhang Hao;Li Qiao Qiao;Yang Feng Qing;Li De Qiang
10 一种基于靶标亲和性的“一体化”中药活性成分筛选方法 专利 李德强;孔德志;尹星烁;张学琴
11 Rapid screening and characterization of natural antioxidants in Polygonum viviparum by an on-line system integrating the pressurised liquid micro-extraction, HPLC-DAD-QTOF-MS/MS analysis and antioxidant assay 期刊论文 Zheng-ming Qian;Ling Chen;Meng-qi Wu;De-qiang Li
12 Simultaneous optimization of ultrasound-assisted extraction of antioxidants and tyrosinase inhibitory activities of Semen Oroxyli flavonoids using response surface methodology 期刊论文 Yin Xing shuo;Zhang Xue qin;Li De qiang
13 Physicochemical characteristics and biological activities of polysaccharides from the leaves of different loquat (Eriobotrya japonica) cultivars 期刊论文 Fu Yuan;Yuan Qin;Lin Shang;Liu Wen;Du Gang;Zhao Li;Zhang Qing;Lin De Rong;Liu Yun Tao;Qin Wen;Li De Qiang;Wu Ding Tao
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