缺血再灌注损伤治疗策略的探索：线粒体靶向治疗药物对线粒体形态及功能的调控

81370419
2013
H0216.周围血管疾病
毕伟
面上项目
主任医师
河北医科大学
70万元
线粒体靶向治疗药物;线粒体动态变化;缺血再灌注损伤;线粒体分裂/融合;药物调控
2014-01-01到2017-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Pharmacological protection of mitochondrial function mitigates acute limb ischemia/reperfusion injury. 期刊论文 Bi Wei;Bi Yue;Gao Xiang;Yan Xin;Zhang Yanrong;Harris Jackie;Legalley Thomas D;Gibson K Michael;Bi Lanrong
2 Anti-inflammatory, analgesic and antioxidant activities of novel kyotorphin-nitroxide hybrid molecules. 期刊论文 Bi Wei;Bi Yue;Gao Xiang;Yan Xin;Zhang Yanrong;Xue Ping;Bammert Catherine E;Legalley Thomas D;Michael Gibson K;Bi Lanrong;Wang Jia-Xiang
3 Indole-TEMPO conjugates alleviate ischemia-reperfusion injury via attenuation of oxidative stress and preservation of mitochondrial function 期刊论文 Bi Wei;Bi Yue;Gao Xiang;Li Pengfei;Hou Shanshan;Zhang Yanrong;Bammert Cathy;Jockusch Steffen;Legalley Thomas D.;Gibson K. Michael;Bi Lanrong
4 Glycine-nitronyl nitroxide conjugate protects human umbilical vein endothelial cells against hypoxia/reoxygenation injury via multiple mechanisms and ameliorates hind limb ischemia/reperfusion injury in rats 期刊论文 Gao Xiang;Bi Yue;Chi Kui;Liu Yang;Yuan Tao;Li Xueyan;Bi Wei
5 Combination of ischemic post-conditioning with a synthetic glycine derivative improves functional outcome after ischemic-reperfusion injury in rats 期刊论文 Gao Xiang;Bi Wei;Liu Shuxia;Liu Qingjuan;Zhang Yanrong;Duan Huijun
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