血管成纤维细胞外泌体调控血管平滑肌细胞表型转化与高血压血管重构的分子机制

91639105
2016
H0202.心肌损伤、修复、重构和再生
朱国庆
重大研究计划
教授
南京医科大学
65万元
血管平滑肌细胞;表型转化;血管重构;高血压;外泌体
2017-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 FNDC5 inhibits foam cell formation and monocyte adhesion in vascular smooth muscle cells via suppressing NF kappa B-mediated NLRP3 upregulation 期刊论文 Zang Ying Hao;Chen Dan;Zhou Bing;Chen Ai Dong;Wang Jue Jin;Gao Xing Ya;Chen Qi;Li Yue Hua;Kang Yu Ming;Zhu Guo Qing
2 Crosstalk between adipose tissues and brain in obesity and hypertension 会议论文 朱国庆
3 Exosome-Mediated Transfer of ACE from Adventitial Fibroblasts of SHR Promotes VSMC Migration 会议论文 朱国庆
4 NLRP3 inflammasome activation and vascular remodeling in Hypertension 会议论文 朱国庆
5 鸢尾素在制备抗糖尿病药物中的应用 专利 朱国庆;熊晓青;刘桐言
6 FNDC5 attenuates adipose tissue inflammation and insulin resistance via AMPK-mediated macrophage polarization in obesity. 期刊论文 Xiong Xiao-Qing;Geng Zhi;Zhou Bing;Zhang Feng;Han Ying;Zhou Ye-Bo;Wang Jue-Jin;Gao Xing-Ya;Chen Qi;Li Yue-Hua;Kang Yu-Ming;Zhu Guo-Qing
7 Silencing salusin-beta attenuates cardiovascular remodeling and hypertension in spontaneously hypertensive rats. 期刊论文 Ren Xing-Sheng;Ling Li;Zhou Bing;Han Ying;Zhou Ye-Bo;Chen Qi;Li Yue-Hua;Kang Yu-Ming;Zhu Guo-Qing
8 Salusin-beta contributes to oxidative stress and inflammation in diabetic cardiomyopathy. 期刊论文 Zhao Ming-Xia;Zhou Bing;Ling Li;Xiong Xiao-Qing;Zhang Feng;Chen Qi;Li Yue-Hua;Kang Yu-Ming;Zhu Guo-Qing
9 Exosomes from vascular fibroblast in proliferation and migration of vascular smooth muscle cells 会议论文 Guo-Qing Zhu
10 NLRP3 inflammasome activation contributes to VSMC phenotypic transformation and proliferation in hypertension. 期刊论文 Sun Hai-Jian;Ren Xing-Sheng;Xiong Xiao-Qing;Chen Yun-Zhi;Zhao Ming-Xia;Wang Jue-Jin;Zhou Ye-Bo;Han Ying;Chen Qi;Li Yue-Hua;Kang Yu-Ming;Zhu Guo-Qing
11 BCL6 attenuates renal inflammation via negative regulation of NLRP3 transcription. 期刊论文 Chen Dan;Xiong Xiao-Qing;Zang Ying-Hao;Tong Ying;Zhou Bing;Chen Qi;Li Yue-Hua;Gao Xing-Ya;Kang Yu-Ming;Zhu Guo-Qing
12 Crosstalk between brain and adipose tissues in Obesity and Hypertension 会议论文 朱国庆
13 Adventitial fibroblasts-derived exosomes in proliferation of vascular smooth muscle cells in hypertension 会议论文 朱国庆
14 Adventitial fibroblasts-derived exosomes in vascular remodeling 会议论文 朱国庆
15 Exosome-Mediated Transfer of ACE (Angiotensin-Converting Enzyme) From Adventitial Fibroblasts of Spontaneously Hypertensive Rats Promotes Vascular Smooth Muscle Cell Migration. 期刊论文 Tong Ying;Ye Chao;Ren Xing-Sheng;Qiu Yun;Zang Ying-Hao;Xiong Xiao-Qing;Wang Jue-Jin;Chen Qi;Li Yue-Hua;Kang Yu-Ming;Zhu Guo-Qing
16 FNDC5 attenuates obesity-induced adipose tissue inflammation via AMPK-mediated macrophage polarization 会议论文 Xiao-Qing Xiong;Zhi Geng;Bing Zhou;ZhangFeng;Ying Han;Ye-Bo Zhou;Jue-Jin Wang;Xing -Ya Gao;Qi Chen;Yue-Hua Li;Yu-Ming Kang;Guo-Qing Zhu
17 MiR155-5p in adventitial fibroblasts-derived extracellular vesicles inhibits vascular smooth muscle cell proliferation via suppressing angiotensin-converting enzyme expression 会议论文 朱国庆
18 Curcumin attenuates migration of vascular smooth muscle cells via inhibiting NF kappa B-mediated NLRP3 expression in spontaneously hypertensive rats 期刊论文 Han Ying;Sun Hai Jian;Tong Ying;Chen Yun Zhi;Ye Chao;Qiu Yun;Zhang Feng;Chen Ai Dong;Qi Xiao Hong;Chen Qi;Li Yue Hua;Kang Yu Ming;Zhu Guo Qing
19 NLRP3 inflammasome activation in hypertension 会议论文 Guo-Qing Zhu
20 BCL6 Attenuates Proliferation and Oxidative Stress of Vascular Smooth Muscle Cells in Hypertension 期刊论文 Chen Dan;Zang Ying Hao;Qiu Yun;Zhang Feng;Chen Ai Dong;Wang Jue Jin;Chen Qi;Li Yue Hua;Kang Yu Ming;Zhu Guo Qing
21 BCL6抑制自发性高血压大鼠肾脏NLRP3炎性小体激活和炎症 会议论文 陈丹;熊晓青;臧英豪;佟影;周兵;陈琪;李跃华;高兴亚;康玉明;朱国庆
22 FNDC5/Irisin改善肝脏糖脂代谢紊乱的作用及分子机制 奖励 刘桐言;朱国庆
23 Exosome-mediated Transfer of Angiotensin Converting Enzyme from Adventitial Fibroblasts of SHR Promotes VSMC Migration 会议论文 佟影;朱国庆
24 FNDC5抑制SHR血管外膜成纤维细胞的NLRP3炎性小体激活和表型转换 会议论文 凌莉;陈丹;佟影;臧英豪;任兴胜;周红;戚晓红;陈琪;李跃华;康玉明;朱国庆
25 NLRP3 Gene Deletion Attenuates Angiotensin II-Induced Phenotypic Transformation of Vascular Smooth Muscle Cells and Vascular Remodeling. 期刊论文 Xing-Sheng Ren;Ying Tong;Li Ling;Dan Chen;Hai-Jian Sun;Hong Zhou;Xiao-Hong Qi;Qi Chen;Yue-Hua Li;Yu-Ming Kang;Guo-Qing Zhu
26 Fibronectin type III domain containing 5 attenuates NLRP3 inflammasome activation and phenotypic transformation of adventitial fibroblasts in spontaneously hypertensive rats. 期刊论文 Ling Li;Chen Dan;Tong Ying;Zang Ying-Hao;Ren Xing-Sheng;Zhou Hong;Qi Xiao-Hong;Chen Qi;Li Yue-Hua;Kang Yu-Ming;Zhu Guo-Qing
27 NLRP3基因敲除减轻AngII诱导的VSMC表型转化和血管重构 会议论文 任兴胜;佟影;凌莉;陈丹;孙海建;周红;戚晓红;陈琪;李跃华;康玉明;朱国庆
28 MiR155-5p in adventitial fibroblasts-derived extracellular vesicles inhibits vascular smooth muscle cell proliferation via suppressing angiotensin-converting enzyme expression. 期刊论文 Ren Xing-Sheng;Tong Ying;Qiu Yun;Ye Chao;Wu Nan;Xiong Xiao-Qing;Wang Jue-Jin;Han Ying;Zhou Ye-Bo;Zhang Feng;Sun Hai-Jian;Gao Xing-Ya;Chen Qi;Li Yue-Hua;Kang Yu-Ming;Zhu Guo-Qing
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