前列腺素E2激活视网膜微血管内皮细胞NLRP3炎症小体促进糖尿病视网膜病变的机制研究
81770941
2017
H1305.视网膜、脉络膜及玻璃体相关疾病
姚勇
面上项目
主任医师
南京医科大学
51万元
前列腺素E2;糖尿病视网膜病变;信号转导通路;NLRP3炎症小体;视网膜微血管损伤
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Prostaglandin E-2/EP2 receptor signalling pathway promotes diabetic retinopathy in a rat model of diabetes | 期刊论文 | Wang Man;Wang Yangningzhi;Xie Tianhua;Zhan Pengfei;Zou Jian;Nie Xiaowei;Shao Jun;Zhuang Miao;Tan Chengye;Tan Jianxin;Dai Youai;Sun Jie;Li Jiantao;Li Yuehua;Shi Qian;Leng Jing;Wang Xiaolu;Yao Yong |
| 2 | Rac1介导的氧化应激在糖尿病视网膜病变中的作用 | 期刊论文 | 张梦圆;魏婷婷;谢田华;姚勇 |
| 3 | TGR5 receptor activation attenuates diabetic retinopathy through suppression of RhoA/ROCK signaling | 期刊论文 | Zhu Lingpeng;Wang Wenjuan;Xie Tian-Hua;Zou Jian;Nie Xiaowei;Wang Xiaolu;Zhang Meng-Yuan;Wang Zhong-Yuan;Gu Shun;Zhuang Miao;Tan Jianxin;Shen Chenyou;Dai Youai;Yang Xusheng;Yao Yong;Wei Ting-Ting |
| 4 | Interferon-c induces retinal pigment epithelial cell Ferroptosis by a JAK1-2/STAT1/SLC7A11 signaling pathway in Age-related Macular Degeneration | 期刊论文 | Ting-Ting Wei;Meng-Yuan Zhang;Xin-Hua Zheng;Tian-Hua Xie;Wenjuan Wang;Jian Zou;Yan Li;Hong-Ying Li;Jiping Cai;Xiaolu Wang;Jianxin Tan;Xusheng Yang;Yong Yao;Lingpeng Zhu |
| 5 | miR-146a对糖尿病视网膜病变炎症反应的抑制作用 | 期刊论文 | 顾顺;詹鹏飞;王文娟;王晓露;魏婷婷;朱凌鹏;王杨宁致;殷丽;谢田华;姚勇 |
| 6 | Protective roles of the TIR/BB-loop mimetic AS-1 in alkali-induced corneal neovascularization by inhibiting ERK phosphorylation | 期刊论文 | Yanqiu Liu;Yishun Shu;Li Yin;Tianhua Xie;Jian Zou;Pengfei Zhan;Yangningzhi Wang;Tingting Wei;Lingpeng Zhu;Xusheng Yang;Wenjuan Wang;Jiping Cai;Yuehua Li;Yong Yao;Xiaolu Wang |
| 7 | Prostaglandin E-2 promotes pathological retinal neovascularisation via EP4R-EGFR-Gab1-AKT signaling pathway | 期刊论文 | Xie Tianhua;Zhang Zhonghong;Cui Yuqing;Shu Yishun;Liu Yanqiu;Zou Jian;Wang Man;Wang Yangningzhi;Yang Qian;Pan Xubin;Cai Jiping;Sun Xiaodong;Yao Yong;Wang Xiaolu |
| 8 | Retinal pigment epithelial cells secrete miR-202-5p-containing exosomes to protect against proliferative diabetic retinopathy | 期刊论文 | Gu Shun;Liu Yixiao;Zou Jian;Wang Wenjuan;Wei Tingting;Wang Xiaolu;Zhu Lingpeng;Zhang Mengyuan;Zhu Jing;Xie Tianhua;Yao Yong;Qiu Liying |
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