应用基于Tetramer技术的致病性CD8 T细胞免疫分型探讨1型糖尿病患者 胰岛损伤异质性的研究
81670715
2016
H0701.内分泌系统免疫相关疾病
徐宽枫
面上项目
研究员
南京医科大学
58万元
致病性T细胞;胰岛损伤;自身免疫;1型糖尿病;四聚体
2017-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Rs2227982 and rs2227981 in PDCD1 gene are functional SNPs associated with T1D risk in East Asian | 期刊论文 | Gu Yong;Xiao Lei;Gu Wei;Chen Shu;Feng Yingjie;Wang Jian;Wang Zhixiao;Cai Yun;Chen Heng;Xu Xinyu;Shi Yun;Zhang Mei;Xu Kuanfeng;Yang Tao |
| 2 | The associations between three genome-wide risk variants for serum C-peptide of T1D and autoantibody-positive T1D risk, and clinical characteristics in Chinese population | 期刊论文 | Feng Yingjie;Zhang Yuyue;Chen Yang;Chen Shu;Shen Min;Fu Qi;He Yunqiang;Liu Yuwei;Hsu Hsiang-Ting;Xu Xinyu;Chen Heng;Yang Tao;Xu Kuanfeng |
| 3 | Identification of Novel T1D Risk Loci and Their Association With Age and Islet Function at Diagnosis in Autoantibody-Positive T1D Individuals: Based on a Two-Stage Genome-Wide Association Study | 期刊论文 | Zhu Meng;Xu Kuanfeng;Chen Yang;Gu Yong;Zhang Mei;Luo Feihong;Liu Yu;Gu Wei;Hu Ji;Xu Haixia;Xie Zhiguo;Sun Chengjun;Li Yuxiu;Sun Min;Xu Xinyu;Hsu Hsiang-Ting;Chen Heng;Fu Qi;Shi Yun;Xu Jingjing;Ji Li;Liu Jin;Bian Lingling;Zhu Jing;Chen Shuang;Xiao Lei;Li Xin;Jiang Hemin;Shen Min;Huang Qianwen... |
| 4 | The association between rs1893217, rs478582 in PTPN2 and T1D risk with different diagnosed age, and related clinical characteristics in Chinese Han population | 期刊论文 | Chen Shu;Fan Hongqi;Feng Yingjie;Zhang Yuyue;Chen Yang;Gu Yong;Shi Yun;Dai Hao;Zhang Mei;Xu Xinyu;Chen Heng;Yang Tao;Xu Kuanfeng |
| 5 | CTLA-4+49 G/A, a functional T1D risk SNP, affects CTLA-4 level in Treg subsets and IA-2A positivity, but not beta-cell function | 期刊论文 | Chen Yang;Chen Shu;Gu Yong;Feng Yingjie;Shi Yun;Fu Qi;Wang Zhixiao;Cai Yun;Dai Hao;Zheng Shuai;Sun Min;Zhang Mei;Xu Xinyu;Chen Heng;Xu Kuanfeng;Yang Tao |
| 6 | 1型糖尿病患者外周血 Treg细胞亚群频率 及 Helios、细胞毒性 T淋巴细胞相关抗原 4 分子表型分析 | 期刊论文 | 陈姝 肖蕾 付麒 许馨予 崔岱 杨涛;徐宽枫 |
| 7 | High Prevalence of a Monogenic Cause in Han Chinese Diagnosed With Type 1 Diabetes, Partly Driven by Nonsyndromic Recessive WFS1 Mutations | 期刊论文 | Li Meihang;Wang Sihua;Xu Kuanfeng;Chen Yang;Fu Qi;Gu Yong;Shi Yun;Zhang Mei;Sun Min;Chen Heng;Han Xiuqun;Li Yangxi;Tang Zhoukai;Cai Lejing;Li Zhiqiang;Shi Yongyong;Yang Tao;Polychronakos Constantin |
| 8 | 人尿液中儿茶酚胺类物质和其甲氧基代谢物含量的检测方法 | 专利 | 孙敏;杨功俊;廖雪琴;陶凯丽;徐宽枫;杨涛 |
| 9 | 2020年南京医科大学优秀硕士学术学位论文指导教师 | 奖励 | 徐宽枫 |
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