核动力舰艇核辐射危害防护应用基础研究
11635014
2016
A30.核技术及其应用
蔡建明
重点项目
教授
中国人民解放军第二军医大学
320万元
相对生物学效应;自由基;细胞辐射敏感性;电离辐射;DNA损伤修复
2017-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 海上作业重要伤病防护与救治关键技术及其体系创新 | 奖励 | 侯立军;蔡建明;戚中田;方以群;徐志飞;赵杰;黄建松;郭俊生;赵平;董艳;廖万清;包瀛春;张丹枫;陈吉钢 |
| 2 | Glibenclamide, a diabetic drug, prevents acute radiation induced liver injury of mice via up-regulating intracellular ROS and subsequently activating Akt-NF-κB pathway | 期刊论文 | Hu Liu;Shichao Wang;Zhao Wu;Ziyun Huang;Wei you Chen;Yanyong Yang;Jianguo Cui;Cong Liu;Hainan Zhao;Jiaming Guo;Pei Zhang;Fu Gao;Bailong Li;Jianming Cai |
| 3 | Radioprotective effects of roxadustat (FG-4592) in haematopoietic system | 期刊论文 | Pei Zhang;Jicong Du;Hainan Zhao;Ying Cheng;Suhe Dong;Yanyong Yang;Bailong Li;Fu Gao;Xuejun Sun;Jianming Cai;Cong Liu |
| 4 | Toll-like receptors and radiation protection | 期刊论文 | Zhe Liu;X Lei;X. LI;Jianming Cai;Fu Gao;Yanyong Yang |
| 5 | MPLA在制备电离辐射致睾丸损伤防治药物中的应用 | 专利 | 刘哲;高福;杨彦勇;蔡建明;曹堃;陈媛媛;雷霄;曲红金;刘蕾;廖泽彬 |
| 6 | 大批量样本点源辐照架 | 专利 | 郭佳铭;马龙;刘婷婷;徐照;刘虎;蔡建明;李桃生;李百龙;郝伟;郭嘉欣 |
| 7 | Heat-killed Salmonella typhimurium mitigated radiation-induced lung injury | 期刊论文 | Cao Kun;Luo Tao;Hu Leiyuan;Fang Yunhao;Wu Ning;Liu Zhe;Chen Yuanyuan;Lei Xiao;Qin Hongran;Cai Jianming;Gao Fu;Yang Yanyong |
| 8 | 核应急医学救援在职培训教学体会 | 期刊论文 | 郭佳铭;赵璐;王玮;高福;李百龙;刘虎 |
| 9 | Zymosan-a Protects the Hematopoietic System from Radiation-Induced Damage by Targeting TLR2 Signaling Pathway. | 期刊论文 | Jicong Du;Ying Cheng;Suhe Dong;Pei Zhang;Jiaming Guo;Jiaqi Han;Fu Gao;Hainan Zhao;Ding Sun;Jianguo Cui;Jianming Cai;Cong Liu |
| 10 | 方格星虫多糖对HUVEC细胞137Cs γ射线损伤的保护作用 | 期刊论文 | 高春丽;王庆蓉;沈先荣;白爽;胡秀婷;何颖 |
| 11 | 酵母多糖在制备防护急性放射性骨髓损伤药物中的应用 | 专利 | 杜继聪;蔡建明;高福;刘聪;程赢;杨彦勇;刘虎;张沛;赵海男;东肃河;韩家琦 |
| 12 | Murabutide在制备电离辐射致骨髓、小肠和脾脏损伤防治药物中应用 | 专利 | 刘蕾;蔡建明;高福;杨彦勇;曲红金;崔建国;廖泽彬;曹堃;陈媛媛;刘哲 |
| 13 | 1-乙酰胺基乙叉-1,1-二膦酸盐及其制备方法与应用 | 专利 | 高福;杨彦勇;蔡建明;李百龙;赵海男;程赢;刘聪;崔建国;陈媛媛 |
| 14 | 化合物CL429抗辐射治疗中的用途 | 专利 | 程赢;杜继聪;刘聪;高福;蔡建明;东肃河;刘虎;施赟杰;刘入菱 |
| 15 | Monophosphoryl lipid a attenuates radiation injury through TLR4 activation | 期刊论文 | Jiaming Guo;Yuanyuan Chen;Xiao Lei;Yang Xu;Zhe Liu;Jianming Cai;Fu Gao;Yanyong Yang |
| 16 | Hypoxia-Induced Mesenchymal Stromal Cells Exhibit an Enhanced Therapeutic Effect on Radiation-Induced Lung Injury in Mice due to an Increased Proliferation Potential and Enhanced Antioxidant Ability | 期刊论文 | Bailong Li;Cheng Li;Mo Zhu;Youjun Zhang;Jicong Du;Yang Xu;Bin Liu;Fu Gao;Hu Liu;Jianming Cai;Yanyong Yang |
| 17 | Heat-killed salmonella typhimurium (HKST) protects mice against radiation in TLR4-dependent manner. | 期刊论文 | Yang Xu;Yuanyuan Chen;Hu Liu;Xiao Lei;Jiaming Guo;Kun Cao;Cong Liu;Bailong Li;Jianming Cai;Jintao Ju;Fu Gao;Yanyong Yang |
| 18 | Monophosphoryl lipid A alleviated radiation-induced testicular injury through TLR4-dependent exosomes | 期刊论文 | Zhe Liu;Kun Cao;Zebin Liao;Yuanyuan Chen;Xiao Lei;Qun Wei;Cong Liu;Xuejun Sun;Yanyong Yang;Jianming Cai;Fu Gao |
| 19 | 葡萄糖胺在制备电离辐射致放射性肺损伤防治药物中的应用 | 专利 | 杨彦勇;高福;蔡建明;雷霄;崔建国;李百龙;郭佳铭;陈媛媛;许洋;刘聪;刘哲 |
| 20 | 格列本脲在制备放射性肺损伤药物中的应用 | 专利 | 蔡建明;高福;刘虎;张沛;李百龙;杨彦勇;杜继聪 |
| 21 | 维生素D在防治辐射所致肠损伤中的用途 | 专利 | 刘虎;夏鹏林;刘入菱;刘婷婷;杨亚杰 |
| 22 | NSC 23766在防治辐射所致肺损伤中的用途 | 专利 | 袁红斌;刘虎;安妮;李振杰 |
| 23 | Effects of 12C6+ Heavy Ion Radiation on Dendritic Cells Function | 期刊论文 | Pei Zhang;Xuguang Hu;Bin Liu;Zhe Liu;Cong Liu;Jianming Cai;Fu Gao;Jianguo Cui;Bailong Li;Yanyong Yang |
| 24 | The mechanism for the radioprotective effects of zymosan-A in mice | 期刊论文 | Jicong Du;Pei Zhang;Hainan Zhao;Suhe Dong;Yanyong Yang;Jianguo Cui;Fu Gao;Jianming Cai;Cong Liu |
| 25 | 缺氧诱导因子与肠道辐射损伤的研究进展 | 期刊论文 | 杜继聪;蔡建明 |
| 26 | NOD2 agonist murabutide alleviates radiation-induced injury through DNA damage response pathway mediated by ATR | 期刊论文 | Lei Liu;Hongjin Qu;Hongran Qin;Yanyong Yang;Zebin Liao;Jianguo Cui;Fu Gao;Jianming Cai |
| 27 | Radiation-induced decrease of CD8+ dendritic cells contributes to Th1/Th2 shift | 期刊论文 | Hu Liu;Bailong Li;Xiaojing Jia;Yan Ma;Yifeng Gu;Pei Zhang;Qun Wei;Jianming Cai;Jianguo Cui;Fu Gao;Yanyong Yang |
| 28 | Polydatin alleviated radiation-induced lung injury through activation of Sirt3 and inhibition of epithelial–mesenchymal transition | 期刊论文 | Kun Cao;Xiao Lei;Hu Liu;Hainan Zhao;Jiaming Guo;Yuanyuan Chen;Yang Xu;Ying Cheng;Cong Liu;Jianguo Cui;Bailong Li;Jianming Cai;Fu Gao;Yanyong Yang |
| 29 | TLR4 Agonist Monophosphoryl Lipid A Alleviated Radiation-Induced Intestinal Injury | 期刊论文 | Jiaming Guo;Zhe Liu;Danfeng Zhang;Yuanyuan Chen;Hongran Qin;Tingting Liu;Cong Liu;Jianguo Cui;Bailong Li;Yanyong Yang;Jianming Cai;Fu Gao |
| 30 | CpG-Oligodeoxynucleotides Improved Irradiation-Induced Injuries by G-CSF and IL-6 Up-Regulation | 期刊论文 | Pei Zhang;Suhe Dong;Jiaming Guo;Yanyong Yang;Cong Liu;Bailong Li;Fu Gao;Xuejun Su;Jianming Cai |
| 31 | 氨来呫诺在制备电离辐射致放射性肺损伤防治药物中的应用 | 专利 | 曲红金;高福;杨彦勇;蔡建明;刘蕾;曹堃;廖泽彬;刘哲;陈媛媛;雷霄 |
| 32 | Long non-coding RNA ANRIL promotes homologous recombination-mediated DNA repair by maintaining ATR protein stability to enhance cancer resistance | 期刊论文 | Lei Liu;Yuanyuan Chen;Yijuan Huang;Kun Cao;Tingting Liu;Hui Shen;Jianguo Cui;Bailong Li;Jianming Cai;Fu Gao;Yanyong Yang |
| 33 | Analysis of miRNA-mRNA Crosstalk in Radiation-Induced Mouse Thymic Lymphomas to Identify miR-486 as a Critical Regulator by Targeting IGF2BP3 mRNA | 期刊论文 | Hainan Zhao;Suhe Dong;Jicong Du;Penglin Xia;Ruling Liu;Tingting Liu;Yajie Yang;Ying Cheng;Jianming Cai;Cong Liu;Fu Gao;Hu Liu |
| 34 | 小鼠肺癌原位荷瘤放疗模型的建立与应用 | 专利 | 高福;杨彦勇;雷霄;蔡建明;崔建国;李百龙;陈媛媛;许洋;刘哲;郭佳铭 |
| 35 | 葡萄糖胺在制备放疗增敏药物中的应用 | 专利 | 雷霄;杨彦勇;蔡建明;高福;李百龙;陈媛媛;许洋;郭佳铭;曹堃;刘哲 |
| 36 | Grape Seed Proanthocyanidins play the roles of radioprotection on Normal Lung and radiosensitization on Lung Cancer via differential regulation of the MAPK Signaling Pathway | 期刊论文 | Yang Xu;Yijuan Huang;Yuanyuan Chen;Kun Cao;Zhe Liu;Zhijie Wan;Zebin Liao;Bailong Li;Jianguo Cui;Yanyong Yang;Xiaohua Xu;Jianming Cai;Fu Gao |
| 37 | Polydatin Attenuates 14.1MeV Neutron-Induced Injuries via Regulating the Apoptosis and Antioxidative Pathways and Improving the Hematopoiesis of Mice | 期刊论文 | Jiaming Guo;Tingting Liu;Long Ma;Wei Hao;Hongli Yan;Taosheng Li;Yanyong Yang;Jianming Cai;Fu Gao;Zhao Xu;Hu Liu |
| 38 | Blocking TBK1 alleviated radiation-induced pulmonary fibrosis and epithelial-mesenchymal transition through Akt-Erk inactivation | 期刊论文 | Hongjin Qu;Lei Liu;Zhe Liu;Hongran Qin;Zebin Liao;Penglin Xia;Yanyong Yang;Bailong Li;Fu Gao;Jianming Cai |
| 39 | Sirt3 Promoted DNA Damage Repair and Radioresistance Through ATM-Chk2 in Non-small Cell Lung Cancer Cells | 期刊论文 | Kun Cao;Yuanyuan Chen;Songyun Zhao;Yijuan Huang;Tingting Liu;Hu Liu;Bailong Li;Jianguo Cui;Jianming Cai;Chong Bai;Yanyong Yang;Fu Gao |
| 40 | 方格星虫多糖对人肠上皮细胞辐射损伤的保护作用 | 期刊论文 | 高春丽;石特;张俊玲;沈先荣;何颖;王庆蓉 |
| 41 | Nuclear Transglutaminase 2 interacts with topoisomerase II⍺ to promote DNA damage repair in lung cancer cells | 期刊论文 | Xiao Lei;Kun Cao;Yuanyuan Chen;Hui Shen;Zhe Liu;Hongran Qin;Jianming Cai;Fu Gao;Yanyong Yang |
| 42 | miR-351基因的应用 | 专利 | 张沛;刘聪;蔡建明;高福;程赢;杨彦勇;刘虎;赵海男;杜继聪;东肃河 |
| 43 | 智能化多功能除放射性沾染仪 | 专利 | 李百龙;蔡建明;高福;程赢;崔建国;刘聪;杨彦勇;刘虎;陈媛媛 |
| 44 | 抑制或下调AKAP12基因表达的试剂在制备肿瘤放疗增敏药物中的应用 | 专利 | 陈媛媛;蔡建明;高福;杨彦勇;雷霄;郭佳铭;李百龙;崔建国;刘哲;许洋;刘蕾;曲红金 |
| 45 | 智能化多功能除放射性沾染装置 | 专利 | 李百龙;蔡建明;高福;程赢;崔建国;刘聪;杨彦勇;刘虎;陈媛媛 |
| 46 | MPLA在制备电离辐射致肠道损伤防治药物中的应用 | 专利 | 杨彦勇;雷霄;蔡建明;崔建国;李百龙;陈媛媛;刘聪;高福;刘哲;许洋;郭佳铭 |
| 47 | 抑制或下调TG2基因表达的试剂在制备肿瘤放疗增敏药物中的应用 | 专利 | 高福;蔡建明;杨彦勇;雷霄;刘哲;崔建国;李百龙;陈媛媛;张沛;许洋;郭佳铭 |
| 48 | 人体体表放射性沾染快速定位测量装置 | 专利 | 李百龙;张中良;蔡建明;高福;程赢;崔建国;刘聪;杨彦勇;刘虎;陈媛媛 |
| 49 | FG-4592在制备防护急性放射性骨髓损伤药物中的应用 | 专利 | 杜继聪;蔡建明;刘聪;张沛;刘虎;程赢;杨彦勇;赵海男;东肃河;韩家琦 |
| 50 | 分子氢与健康 | 专著 | 蔡建明 |
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