ABCC3基因表达及其mRNA剪接变异对氯吡格雷抵抗的影响
81473286
2014
H3511.临床药理
谢红光
面上项目
教授
南京医科大学
85万元
氯吡格雷抵抗;氯吡格雷;ABCC3;冠心病;可变剪接
2015-01-01到2018-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Enhanced platelet response to clopidogrel in Abcc3-deficient mice due to its increased bioactivation | 期刊论文 | Tai T;Mi QY;Ji JZ;Yin Q;Pan YQ;Zhang MR;Huang BB;Xie HG |
| 2 | Interleukin-10 does not modulate clopidogrel platelet response in mice | 期刊论文 | Yin Q;Tai T;Ji JZ;Mi QY;Zhang MR;Huang WJ;Cao CC;Xie HG |
| 3 | Human UGT2B7 is the major isoform responsible for the glucuronidation of clopidogrel carboxylate | 期刊论文 | Ji JZ;Huang BB;Gu TT;Tai T;Zhou H;Jia YM;Mi QY;Zhang MR;Xie HG |
| 4 | Aspirin attenuates the bioactivation of and platelet response to vicagrel in mice | 期刊论文 | Jia YM;Gu TT;Ji JZ;Tai T;Zhang MR;Huang BB;Zhou H;Mi QY;Xie HG |
| 5 | MRP3 transports clopidogrel acyl glucuronide from the hepatocytes into blood | 期刊论文 | Ji JZ;Tai T;Huang BB;Gu TT;Mi QY;Xie HG |
| 6 | Overcoming clopidogrel resistance: Three promising novel antiplatelet drugs developed in China | 期刊论文 | Xie HG;Jia YM;Tai T;Ji JZ |
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