TRAF7/AKT/β-catenin/TCF正反馈调控环路异常在胶质瘤发生发展中的作用及分子机制研究
81872061
2018
H1803.肿瘤细胞命运
石翠娟
面上项目
副研究员
天津医科大学
57万元
AKT信号通路;胶质瘤;泛素化调控;TRAF7;胶质瘤发生
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Improved Antiglioblastoma Activity and BBB Permeability by Conjugation of Paclitaxel to a Cell‐Penetrative MMP‐2‐Cleavable Peptide | 期刊论文 | Dan Hua;Lida Tang;Weiting Wang;Sheng-An Tang;Lin Yu;Xuexia Zhou;Qian Wang;Cuiyun Sun;Cuijuan Shi;Wenjun Luo;Zhendong Jiang;Huining Li;Shizhu Yu |
| 2 | The ATPase Pontin is a key cell cycle regulator by amplifying E2F1 transcription response in glioma | 期刊论文 | Run Wang;Xuebing Li;Cuiyun Sun;Lin Yu;Dan Hua;Cuijuan Shi;Qian Wang;Chun Rao;Wenjun Luo;Zhendong Jiang;Xuexia Zhou;Shizhu Yu |
| 3 | The novel chromatin architectural regulator SND1 promotes glioma proliferation and invasion and predicts the prognosis of patients | 期刊论文 | Lin Yu;Jinling Xu;Jing Liu;Huibian Zhang;Cuiyun Sun;Qian Wang;Cuijuan Shi;Xuexia Zhou;Dan Hua;Wenjun Luo;Xiu-Wu Bian;Shizhu Yu |
| 4 | miR-135a-5p Functions as a Glioma Proliferation Suppressor by Targeting Tumor Necrosis Factor Receptor–Associated Factor 5 and Predicts Patients' Prognosis | 期刊论文 | Wenjun Luo;Cuiyun Sun;Junhu Zhou;Qian Wang;Lin Yu;Xiu-Wu Bian;Xuexia Zhou;Dan Hua;Run Wang;Chun Rao;Zhendong Jiang;Cuijuan Shi;Shizhu Yu |
| 5 | Eucalyptal A inhibits glioma by rectifying oncogenic splicing of MYO1B mRNA via suppressing SRSF1 expression | 期刊论文 | Dan Hua;Qian Zhao;Yang Yu;Huan Yu;Lin Yu;Xuexia Zhou;Qian Wang;Cuiyun Sun;Cuijuan Shi;Wenjun Luo;Zhendong Jiang;Weiting Wang;Lingli Wang;Dongli Zhang;Shengan Tang;Shizhu Yu |
| 6 | Splicing factor SRSF1 promotes gliomagenesis via oncogenic splice-switching of MYO1B. | 期刊论文 | Zhou Xuexia;Wang Run;Li Xuebing;Yu Lin;Hua Dan;Sun Cuiyun;Shi Cuijuan;Luo Wenjun;Rao Chun;Jiang Zhendong;Feng Ying;Wang Qian;Yu Shizhu |
| 7 | MiRNA⁃449b表达减少是导致胶质瘤细胞增殖和侵袭能力增强的重要因素 | 期刊论文 | 饶春;石翠娟;王虔;罗文君;孙翠云;周雪霞;华丹;周俊虎;王润;蒋振东;于士柱 |
| 8 | Recruitment of LEF1 by Pontin chromatin modifier amplifies TGFBR2 transcription and activates TGFβ/SMAD signalling during gliomagenesis | 期刊论文 | Xuexia Zhou;Xuebing Li;Run Wang;Dan Hua;Cuiyun Sun;Lin Yu;Cuijuan Shi;Wenjun Luo;Zhendong Jiang;Wenzhe An;Qian Wang;Shizhu Yu |
| 9 | The RNA-binding protein SRSF1 is a key cell cycle regulator via stabilizing NEAT1 in glioma | 期刊论文 | Xuexia Zhou;Xuebing Li;Lin Yu;Run Wang;Dan Hua;Cuijuan Shi;Cuiyun Sun;Wenjun Luo;Chun Rao;Zhendong Jiang;Qian Wang;Shizhu Yu |
| 10 | miR-29s function as tumor suppressors in gliomas by targeting TRAF4 and predict patient prognosis | 期刊论文 | Cuijuan Shi;Chun Rao;Cuiyun Sun;Lin Yu;Xuexia Zhou;Dan Hua;Run Wang;Wenjun Luo;Zhendong Jiang;Junhu Zhou;Qian Wang;Shizhu Yu |
| 11 | The miR-29 family members induce glioblastoma cell apoptosis by targeting cell division cycle 42 in a p53-dependent manner | 期刊论文 | Shi C;Luo W;Sun C;Yu L;Zhou X;Hua D;Jiang Z;Wang Q;Yu S |
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