解析E2F1/miR-19a/PPARα反馈环路在胶质瘤细胞代谢和生长过程中的调控作用及其机理
81372709
2013
H1807.肿瘤代谢
刘宁
面上项目
主任医师
南京医科大学
70万元
PPARα;反馈环路;代谢;中枢神经系统肿瘤;C15_脑
2014-01-01到2017-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | CBX7 is a glioma prognostic marker and induces G(1)/S arrest via the silencing of CCNE1 | 期刊论文 | Yu Tianfu;Wu Youzhi;Hu Qi;Zhang Junxia;Nie Er;Wu Weining;Wang Xiefeng;Wang Yingyi;Liu Ning |
| 2 | Polycomb group expression signatures in the malignant progression of gliomas | 期刊论文 | Hu Qi;Wu Weining;Zeng Ailiang;Yu Tianfu;Shen Feng;Nie Er;Wang Yingyi;Liu Ning;Zhang Junxia;You Yongping |
| 3 | MiR-124 governs glioma growth and angiogenesis and enhances chemosensitivity by targeting R-Ras and N-Ras. | 期刊论文 | Shi Zhumei;Chen Qiudan;Li Chongyong;Wang Lin;Qian Xu;Jiang Chengfei;Liu Xue;Wang Xiefeng;Li Hai;Kang Chunsheng;Jiang Tao;Liu Ling-Zhi;You Yongping;Liu Ning;Jiang Bing-Hua |
| 4 | Fenofibrate induces G0/G1 phase arrest by modulating the PPARalpha/FoxO1/p27 kip pathway in human glioblastoma cells. | 期刊论文 | Han Dong-feng;Zhang Jun-xia;Wei Wen-jin;Tao Tao;Hu Qi;Wang Ying-yi;Wang Xie-feng;Liu Ning;You Yong-ping |
| 5 | CBX7 negatively regulates migration and invasion in glioma via Wnt/beta-catenin pathway inactivation | 期刊论文 | Bao Zhongyuan;Xu Xiupeng;Liu Yinlong;Chao Honglu;Lin Chao;Li Zheng;You Yongping;Liu Ning;Ji Jing |
| 6 | PKM2 promotes glucose metabolism and cell growth in gliomas through a mechanism involving a let-7a/c-Myc/hnRNPA1 feedback loop | 期刊论文 | Luan Wenkang;Wang Yingyi;Chen Xincheng;Shi Yan;Wang Jiajia;Zhang Junxia;Qian Jin;Li Ri;Tao Tao;Wei Wenjin;Hu Qi;Liu Ning;You Yongping |
| 7 | MiR-143 acts as a tumor suppressor by targeting N-RAS and enhances temozolomide-induced apoptosis in glioma. | 期刊论文 | Wang Lin;Shi Zhu-Mei;Jiang Cheng-Fei;Liu Xue;Chen Qiu-Dan;Qian Xu;Li Dong-Mei;Ge Xin;Wang Xie-Feng;Liu Ling-Zhi;You Yong-Ping;Liu Ning;Jiang Bing-Hua |
| 8 | Disruption of the EZH2/miRNA/beta-catenin signaling suppresses aerobic glycolysis in glioma | 期刊论文 | Wang Yingyi;Wang Min;Wei Wenjin;Han Dongfeng;Chen Xincheng;Hu Qi;Yu Tianfu;Liu Ning;You Yongping;Zhang Junxia |
| 9 | An Axis Involving SNAI1, microRNA-128 and SP1 Modulates Glioma Progression | 期刊论文 | Dong Qingsheng;Cai Ning;Tao Tao;Zhang Rui;Yan Wei;Li Rui;Zhang Junxia;Luo Hui;Shi Yan;Luan Wenkang;Zhang Yaxuan;You Yongping;Wang Yingyi;Liu Ning |
| 10 | A pseudogene-signature in glioma predicts survival | 期刊论文 | Gao Kai-Ming;Chen Xin-cheng;Zhang Jun-xia;Wang Yingyi;Yan Wei;You Yong-Ping |
| 11 | PPARalpha, a predictor of patient survival in glioma, inhibits cell growth through the E2F1/miR-19a feedback loop. | 期刊论文 | Shi Yan;Tao Tao;Liu Ning;Luan WenKang;Qian Jin;Li Rui;Hu Qi;Wei Yan;Zhang Junxia;You Yongping |
| 12 | NF-kappaB/RelA-PKM2 mediates inhibition of glycolysis by fenofibrate in glioblastoma cells. | 期刊论文 | Han Dongfeng;Wei Wenjin;Chen Xincheng;Zhang Yaxuan;Wang Yingyi;Zhang Junxia;Wang Xiefeng;Yu Tianfu;Hu Qi;Liu Ning;You Yongping |
| 13 | The SIRT2 Polymorphism rs10410544 and Risk of Alzheimer's Disease: A Meta-analysis | 期刊论文 | Wei Wenjin;Xu Xiupeng;Li Hailin;Zhang Yaxuan;Han Dongfeng;Wang Yingyi;Yan Wei;Wang Xiefeng;Zhang Junxia;Liu Ning;You Yongping |
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