M2型小胶质细胞外泌体通过调控脑组织免疫炎症反应改善颅脑创伤认知功能预后的作用及机制研究

81772060
2017
H1701.创伤
雷平
面上项目
教授
天津医科大学
56万元
免疫炎症反应;miR-21-5p;创伤性颅脑损伤;外泌体;认知功能障碍
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
查看更多信息请先登录或注册
查看更多信息请先登录或注册
查看更多信息请先登录或注册
重置
序号 标题 类型 作者
1 Mesenchymal stem cell-derived exosome: a promising alternative in the therapy of Alzheimer’s disease 期刊论文 Mengtian Guo;Zhenyu Yin;Fanglian Chen;Ping Lei
2 Increased miR-124-3p in microglial exosomes following traumatic brain injury inhibits neuronal inflammation and contributes to neurite outgrowth via their transfer into neurons 期刊论文 Shan Huang;Xintong Ge;Jinwen Yu;Zhaoli Han;Zhenyu Yin;Ying Li;Fanglian Chen;Haichen Wang;Jianning Zhang;Ping Lei
3 Exosomes from MiR-21-5p-Increased Neurons Play a Role in Neuroprotection by Suppressing Rab11a-Mediated Neuronal Autophagy In Vitro After Traumatic Brain Injury 期刊论文 Dai Li;Shan Huang;Jialin Zhu;Tianpeng Hu;Zhaoli Han;Shishuang Zhang;Jing Zhao;Fanglian Chen;Ping Lei
4 A novel repetitive mild traumatic brain injury mouse model for chronic traumatic encephalopathy research 期刊论文 Ge Xintong;Yu Jinwen;Huang Shan;Yin Zhenyu;Han Zhaoli;Chen Fanglian;Wang Zengguang;Zhang Jianning;Lei Ping
5 Increased miR-21-3p in injured brain microvascular endothelial cells following traumatic brain injury aggravates blood-brain barrier damage by promoting cellular apoptosis and inflammation through targeting MAT2B 期刊论文 Xintong Ge;Wenzhu Li;Shan Huang;Zhenyu Yin;Mengchen Yang;Zhenying Han;Zhaoli Han;Fanglian Chen;Haichen Wang;Ping Lei;Jianning Zhang
6 Neuron-derived exosomes with high miR-21-5p expression promoted polarization of M1 microglia in culture 期刊论文 Zhenyu Yin;Zhaoli Han;Tianpeng Hu;Shishuang Zhang;Xintong Ge;Shan Huang;Lu Wang;Jinwen Yu;Wenzhu Li;Yan Wang;Dai li;Jing Zhao;Yifeng Wang;Yan Zuo;Ying Li;Xiaodong Kong;Fanglian Chen;Ping Lei
7 Hydrogen Gas Treatment Improves the Neurological Outcome After Traumatic Brain Injury Via Increasing miR-21 Expression 期刊论文 wang L;Zhao C;Wu S;Xiao G;Zhuge Xin;Lei P;Xieke L
8 The pathological role of NLRs and AIM2 inflammasome-mediated pyroptosis in damaged blood-brain barrier after traumatic brain injury 期刊论文 Xintong Ge;Wenzhu Li;Shan Huang;Zhenyu Yin;Xin Xu;Fanglian Chen;Xiaodong Kong;Haichen Wang;Jianning Zhang;Ping Lei
9 Increases in miR-124-3p in Microglial Exosomes Confer Neuroprotective Effects by Targeting FIP200-Mediated Neuronal Autophagy Following Traumatic Brain Injury 期刊论文 Li Dai;Huang Shan;Yin Zhenyu;Zhu Jialin;Ge Xintong;Han Zhaoli;Tan Jin;Zhang Shishuang;Zhao Jing;Chen Fanglian;Wang Haichen;Lei Ping
10 Increased Microglial Exosomal miR-124-3p Alleviates Neurodegeneration and Improves Cognitive Outcome after rmTBI 期刊论文 Xintong Ge;Mengtian Guo;Tianpeng Hu;Wenzhu Li;Shan Huang;Zhenyu Yin;Ying Li;Fanglian Chen;Luoyun Zhu;Chunsheng Kang;Rongcai Jiang;Ping Lei;Jianning Zhang
查看更多信息请先登录或注册

相关项目

趋势报告

经验分享