基于荧光共振能量传递机制构建的组织蛋白酶B激活型阿霉素前药体系的设计合成、生物成像与药物活性评价研究

21807039
2018
B0701.生物体系分子探针
孔秀琪
青年科学基金项目
副教授
济南大学
25万元
组织蛋白酶B;荧光共振能量传递;生物成像;近红外;阿霉素前药
2019-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Development of an esterase fluorescent probe based on naphalimide-benzothiazole conjugation and its applications for qualitative detection of esterase in orlistat-treated biosamples 期刊论文 Yin Yaguang;Kong Xuqi;Li Min;Wang Jingchao;Dai Xiaoyu;Zhang Yunyan;Lin Weiying
2 A novel two-photon fluorescent probe for detecting FA based on a coumarin derivative and its applications in living cells, zebrafish and tissues 期刊论文 Li Min;Kong Xiuqi;Dong Baoli;Zhang Nan;Song Wenhui;Lu Yaru;Lin Weiying
3 Engineering an AIE N2H4 fluorescent probe based on α-cyanostilbene derivative with large Stokes shift and its versatile applications in solution, solid-state and biological systems 期刊论文 Kong Xiuqi;Li Min;Zhang Yunyan;Yin Yaguang;Lin Weiying
4 The development of a hemicyanine-based ratiometric CO fluorescent probe with a long emission wavelength and its applications for imaging COin vitroandin vivo 期刊论文 Zhang Yunyan;Kong Xiuqi;Tang Yonghe;Li Min;Yin Yaguang;Lin Weiying
5 Simultaneously imaging of SO2 in lysosomes and mitochondria based on a dual organelle-targeted fluorescent probe 期刊论文 Kong Xiuqi;Yin Junling;Li Min;Zhu Linlin;Dong Baoli;Ma Yanyan;Lin Weiying
6 An endoplasmic reticulum targetable turn-on fluorescence probe for imaging application of carbon monoxide in living cells 期刊论文 Zhang Yunyan;Tang Yonghe;Kong Xiuqi;Lin Weiying
7 An Ultrasensitivity Fluorescent Probe Based on the ICT-FRET Dual Mechanisms for Imaging beta-Galactosidase in Vitro and ex Vivo 期刊论文 Kong Xiuqi;Li Min;Dong Baoli;Yin Yaguang;Song Wenhui;Lin Weiying
8 A novel red-emitting two-photon fluorescent probe for imaging nitroreductases in cancer cells and tumor tissues with hypoxia conditions. 期刊论文 Li Min;Kong Xuqi;Yin Yaguang;Zhang Yunyan;Dai Xiaoyu;Wang Jingchao;Lin Weiying
9 A near-infrared and two-photon dual-mode fluorescent probe for the colorimetric monitoring of SO(2)in vitro and in vivo 期刊论文 Kong Xiuqi;Li Min;Dong Baoli;Zhang Nan;Song Wenhui;Lu Yaru;Lin Weiying
10 The development of a biotin-guided and mitochondria-targeting fluorescent probe for detecting SO2 precisely in cancer cells. 期刊论文 Zhang Yunyan;Kong Xuqi;Li Min;YinYaguang;Lin Weiying
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