新型靶向配体CL429防治辐射损伤的作用及机制
81872559
2018
H29.放射医学
刘聪
面上项目
教授
中国人民解放军第二军医大学
58万元
CL429;TLR2;电离辐射;NOD2;辐射损伤
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Analysis of miRNA-mRNA Crosstalk in Radiation-Induced Mouse Thymic Lymphomas to Identify miR-486 as a Critical Regulator by Targeting IGF2BP3 mRNA | 期刊论文 | Hainan Zhao;Suhe Dong;Jicong Du;Penglin Xia;Ruling Liu;Tingting Liu;Yajie Yang;Ying Cheng;Jianming Cai;Cong Liu;Fu Gao;Hu Liu |
| 2 | Zymosan-A promotes the regeneration of intestinal stem cells by upregulating ASCL2 | 期刊论文 | Jicong Du;Lan Fang;Jianpeng Zhao;Yike Yu;Zhenlan Feng;Yuedong Wang;Ying Cheng;Bailong Li;Fu Gao;Cong Liu |
| 3 | Toll‐like receptor 4 regulates spontaneous intestinal tumorigenesis by up‐regulating IL‐6 and GM‐CSF | 期刊论文 | Yun‐Jie Shi;Quan‐Quan Zhao;Xiao‐Shuang Liu;Su‐He Dong;Ji‐Fu E;Xu Li;Cong Liu;Hao Wang |
| 4 | 化合物CL429 抗辐射治疗中的用途 | 专利 | 程赢;杜继聪;刘聪;高福;蔡建明;东肃河;刘虎;施赟杰;刘入菱 |
| 5 | CRX-527 induced differentiation of HSCs protecting the intestinal epithelium from radiation damage | 期刊论文 | Dongshu Liu;Suhe Dong;Cong Liu;Jicong Du;Sinian Wang;Huijie Yu;Wei Li;Zhongmin Chen;Renjun Peng;Qisheng Jiang;Mengying Zou;Fengsheng Li;Rong Zhang |
| 6 | Novel chimeric TLR2/NOD2 agonist CL429 exhibited significant radioprotective effects in mice | 期刊论文 | Ying Cheng;Jicong Du;Ruling Liu;Suhe Dong;Jianming Cai;Fu Gao;Cong Liu |
| 7 | TLR2下游辐射防护关键miRNA筛选及miR-21功能验证 | 期刊论文 | 杜继聪;刘入菱;程赢;蔡建明;高福;刘聪 |
| 8 | Toll-like receptor 4 (TLR4) deficiency aggravates dextran sulfate sodium (DSS)-induced intestinal injury by down-regulating IL6, CCL2 and CSF3 | 期刊论文 | Shi Yunjie;Shi-Jie Hu;Zhao Quanquan;Xiao-Shuang Liu;Cong Liu;Hao Wang |
| 9 | CL419在制备治疗炎性肠病药物中的用途 | 专利 | 王灏;刘聪;施贇杰;赵权权;胡世杰;杜继聪 |
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