微小RNA let-7f/mir-27b促进内皮祖细胞修复糖尿病血管损伤的机制

81130004
2011
H0202.心肌损伤、修复、重构和再生
陈丰原
重点项目
教授
中国人民解放军第二军医大学
260万元
血管新生;mir-27b;微小RNA;let-7f;糖尿病
2012-01-01到2016-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Thrombospondin-1/CD36 pathway contributes to bone marrow-derived angiogenic cell dysfunction in type 1 diabetes via Sonic hedgehog pathway suppression 期刊论文 Wang, Jie-Mei|Isenberg, Jeffery S|Billiar, Timothy R|Chen, Alex F|
2 GTP cyclohydrolase I prevents diabetic-impaired endothelial progenitor cells and wound healing by suppressing oxidative stress/thrombospondin-1 期刊论文 Chen, Dan-Dan|Xie, He-Hui|Channon, Keith M|Chen, Alex F|
3 Hypoxic trophoblast HMGB1 induces endothelial cell hyperpermeability via the TRL-4/caveolin-1 pathway 期刊论文 Xia, Aibin|Xue, Min|Zhou, Shenghua|Chen, Alex F|
4 Hydrogen sulfide improves wound healing via restoration of endothelial progenitor cell functions and activation of angiopoietin-1 in type 2 diabetes 期刊论文 Xie, He-Hui|Yuan, Hong|Jia, Weiping|Chen, Alex F|
5 Prolonged Fasting Improves Endothelial Progenitor Cell-Mediated Ischemic Angiogenesis in Mice. 期刊论文 Dong, Xiao-Hui|Zhang, Chuan|Chen, Alex F|Xie, He-Hui|
6 Dietary intake of sugar substitutes aggravates cerebral ischemic injury and impairs endothelial progenitor cells in mice 期刊论文 Sun, Xin|Jiang, Guo-Jun|Chen, Alex F|Xie, He-Hui|
7 Inhibition of PKR impairs angiogenesis through a VEGF pathway 期刊论文 Wu, Jinze|Cai, Jingjing|Zhou, Shenghua|Chen, Alex F|
8 HMGB1-Driven Inflammation and Intimal Hyperplasia After Arterial Injury Involves Cell-Specific Actions Mediated by TLR4 期刊论文 Hackam, David J|Tracey, Kevin J|Billiar, Timothy R|Chen, Alex F|
9 MicroRNA miR-27b rescues bone marrow-derived angiogenic cell function and accelerates wound healing in type 2 diabetes mellitus 期刊论文 Irani, Kaikobad|Wang, Qinde|Yuan, Hong|Chen, Alex F|
10 Oxidative stress-mediated thrombospondin-2 upregulation impairs bone marrow-derived angiogenic cell function in diabetes mellitus 期刊论文 Baek, Seung-Hoon|Wang, Qingde|Yuan, Hong|Chen, Alex F|
11 Combination Therapy of Nifedipine and Sulphonylureas Exhibits a Mutual Antagonistic Effect on the Endothelial Cell Dysfunction Induced by Hyperglycemia Linked to Vascular Disease. 期刊论文 Peng, Cheng|Zhang, Chuan|Tao, Xia|Xie, He-Hui|
12 Thrombospondin-1/CD36 pathway contributes to bone marrow-derived angiogenic cell dysfunction in type 1 diabetes via Sonic hedgehog pathway suppression 期刊论文 Wang, Jie-Mei|Isenberg, Jeffery S|Billiar, Timothy R|Chen, Alex F|
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