人工设计糖基化调控酶耐热性的研究

21506011
2015
B0812.生物化工与合成生物工程
冯旭东
青年科学基金项目
副研究员
北京理工大学
21万元
生物催化;结构模拟;耐热性;理性改造;糖基化
2016-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Enhanced production of beta-glucuronidase from Penicillium purpurogenum Li-3 by optimizing fermentation and downstream processes 期刊论文 Shen Huang;Xudong Feng;Chun Li
2 Enhancing the thermostability of β-glucuronidase by rationally redesigning the catalytic domain based on sequence alignment strategy 期刊论文 Xudong Feng;Heng Tang;Beijia Han;Bo Lv;Chun Li
3 酶的改造及其催化工程应用 期刊论文 冯旭东;李春
4 Enhanced production of glycyrrhetic acid 3-O-mono-β-d-glucuronide by fed-batch fermentation using pH and dissolved oxygen as feedback parameters 期刊论文 Bo Lv;Xudong Feng;Chun Li
5 酶分子稳定性改造研究进展 期刊论文 冯旭东;吕波;李春
6 Engineering the thermostability of β-glucuronidase from Penicillium purpurogenum Li-3 by loop transplant 期刊论文 Xudong Feng;Heng Tang;Beijia Han;Liang Zhang;Bo Lv;Chun Li
7 Biosynthesis of glycyrrhetinic acid-3-O-monoglucose using glycosyltransferase UGT73C11 from Barbarea vulgaris 期刊论文 Xiaochen Liu;Liang Zhang;Xudong Feng;Bo Lv;Chun Li
8 Perspective on biotransformation and de novo biosynthesis of licorice constituents 期刊论文 Yujia Zhao;Bo Lv;Xudong Feng;Chun Li
9 Design of glyco-linkers at multiple structural levels to modulate protein stability 期刊论文 Xudong Feng;Xiaoyan Wang;Beijia Han;Changling Zou;Yuhui Hou;Lina Zhao;Chun Li
10 A novel β-glucuronidase from Talaromyces pinophilus Li-93 precisely hydrolyzes glycyrrhizin into glycyrrhetinic acid 3-O-mono-β-D-glucuronide 期刊论文 Yinghua Xu;Xudong Feng;Jintong Jia;Xinyi Chen;Tian Jiang;Aamir Rasool;Bo Lv;Liangti Qu;Chun Li
11 Enhancing oleanolic acid production in engineered Saccharomyces cerevisiae 期刊论文 Yujia Zhao;Jingjing Fan;Chen Wang;Xudong Feng;Chun Li
12 一种人工设计糖基修饰提高酶热稳定性的方法 专利 李春;王小艳;冯旭东;樊艳爽
13 Structure-guided engineering of the substrate specificity of a fungal beta-glucuronidase toward triterpenoid saponins 期刊论文 Bo Lv;Hanli Sun;Shen Huang;Xudong Feng;Tao Jiang;Chun Li
14 Computation-aided rational deletion of C-terminal region improved the stability, activity, and expression level of GH2 β-glucuronidase 期刊论文 Beijia Han;Yuhui Hou;Tian Jiang;Bo Lv;Lina Zhao;Xudong Feng;Chun Li
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