组蛋白甲基转移酶G9a参与肿瘤细胞脂代谢的机制研究
81530074
2015
H18.肿瘤学
朱卫国
重点项目
教授
深圳大学
273万元
软脂酸;油酸;G9a;染色质
2016-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | G9a coordinates with the RPA complex to promote DNA damage repair and cell survival | 期刊论文 | Yang Qiaoyan;Zhu Qian;Lu Xiaopeng;Du Yipeng;Cao Linlin;Shen Changchun;Hou Tianyun;Li Meiting;Li Zhiming;Liu Chaohua;Wu Di;Xu Xingzhi;Wang Lina;Wang Haiying;Zhao Ying;Yang Yang;Zhu Wei Guo |
| 2 | SIRT6 coordinates with CHD4 to promote chromatin relaxation and DNA repair | 期刊论文 | Hou Tianyun;Cao Ziyang;Zhang Jun;Tang Ming;Tian Yuan;Li Yinglu;Lu Xiaopeng;Chen Yongcan;Wang Hui;Wei Fu-Zheng;Wang Lina;Yang Yang;Zhao Ying;Wang Zimei;Wang Haiying;Zhu Wei-Guo |
| 3 | PTK2-mediated degradation of ATG3 impedes cancer cells susceptible to DNA damage treatment | 期刊论文 | Ma Ke;Fu Wan;Tang Ming;Zhang Chaohua;Hou Tianyun;Li Ran;Lu Xiaopeng;Wang Yanan;Zhou Jingyi;Li Xue;Zhang Luyao;Wang Lina;Zhao Ying;Zhu Wei-Guo |
| 4 | WDFY2 Potentiates Hepatic Insulin Sensitivity and Controls Endosomal Localization of the Insulin Receptor and IRS1/2 | 期刊论文 | Zhang Luyao;Li Xue;Zhang Nan;Yang Xin;Hou Tianyun;Fu Wan;Yuan Fengjie;Wang Lina;Wen He;Tian Yuan;Zhang Hongquan;Lu Xifeng;Zhu Wei-Guo |
| 5 | Destabilization of linker histone H1.2 is essential for ATM activation and DNA damage repair | 期刊论文 | Li Zhiming;Li Yinglu;Tang Ming;Peng Bin;Lu Xiaopeng;Yang Qiaoyan;Zhu Qian;Hou Tianyun;Li Meiting;Liu Chaohua;Wang Lina;Xu Xingzhi;Zhao Ying;Wang Haiying;Yang Yang;Zhu Wei Guo |
| 6 | JCA International Award for Outstanding Achievement (国际肿瘤研究贡献奖) | 奖励 | 朱卫国 |
| 7 | IKK epsilon phosphorylates kindlin-2 to induce invadopodia formation and promote colorectal cancer metastasis | 期刊论文 | Liu Ge;Bao Yantao;Liu Chaohua;Zhu Qinchang;Zhao Lin;Lu Xiaopeng;Zhu Qian;Lv Yafei;Bai Feng;Wen He;Sun Yujie;Zhu Wei-Guo |
| 8 | A specific assay for JmjC domain-containing lysine demethylase and its application to inhibitor screening | 期刊论文 | Wen He;Li Guo;Chen Yongcan;Li Meiting;Lv Yafei;Li Zhiming;Li Yinglu;Hou Tianyun;Wang Hui;Liu Chaohua;Lu Xiaopeng;Zhu Qian;Bao Yantao;Liu Ge;Li Xiaofan;Zhu Wei Guo |
| 9 | p53 cooperates with SIRT6 to regulate cardiolipin de novo biosynthesis | 期刊论文 | Li Meiting;Hou Tianyun;Gao Tian;Lu Xiaopeng;Yang Qiaoyan;Zhu Qian;Li Zhiming;Liu Chaohua;Mu Guanqun;Liu Ge;Bao Yantao;Wen He;Wang Lina;Wang Haiying;Zhao Ying;Gu Wei;Yang Yang;Zhu Wei Guo |
| 10 | 一种评价组蛋白赖氨酸去甲基转移酶活性的方法 | 专利 | 文赫;朱卫国;刘向宇 |
| 11 | CBP mediated DOT1L acetylation confers DOT1L stability and promotes cancer metastasis | 期刊论文 | Liu Chaohua;Yang Qiaoyan;Zhu Qian;Lu Xiaopeng;Li Meiting;Hou Tianyun;Li Zhiming;Tang Ming;Li Yinglu;Wang Hui;Yang Yang;Wang Haiying;Zhao Ying;Wen He;Liu Xiangyu;Mao Zebin;Zhu Wei-Guo |
| 12 | SIRT7 activates p53 by enhancing PCAF-mediated MDM2 degradation to arrest the cell cycle | 期刊论文 | Lu Ya-Fei;Xu Xiao-Peng;Lu Xiao-Peng;Zhu Qian;Liu Ge;Bao Yan-Tao;Wen He;Li Ying-Lu;Gu Wei;Zhu Wei-Guo |
| 13 | GLP-catalyzed H4K16me1 promotes 53BP1 recruitment to permit DNA damage repair and cell survival | 期刊论文 | Lu Xiaopeng;Tang Ming;Zhu Qian;Yang Qiaoyan;Li Zhiming;Bao Yantao;Liu Ge;Hou Tianyun;Lv Yafei;Zhao Ying;Wang Haiying;Yang Yang;Cheng Zhongyi;Wen He;Liu Baohua;Xu Xingzhi;Gu Luo;Zhu Wei-Guo |
| 14 | SIRT7-mediated ATM deacetylation is essential for its deactivation and DNA damage repair | 期刊论文 | Tang Ming;Li Zhiming;Zhang Chaohua;Lu Xiaopeng;Tu Bo;Cao Ziyang;Li Yinglu;Chen Yongcan;Jiang Lu;Wang Hui;Wang Lina;Wang Jiadong;Liu Baohua;Xu Xingzhi;Wang Haiying;Zhu Wei-Guo |
| 15 | UNG2 deacetylation confers cancer cell resistance to hydrogen peroxide-induced cytotoxicity. | 期刊论文 | Bao Yantao;Tong Lili;Song Boyan;Liu Ge;Zhu Qian;Lu Xiaopeng;Zhang Jun;Lu Yafei;Wen He;Tian Yuan;Sun Yujie;Zhu Wei-Guo |
| 16 | A novel acridine derivative, LS-1-10 inhibits autophagic degradation and triggers apoptosis in colon cancer cells | 期刊论文 | Fu Wan;Li Xue;Lu Xiaopeng;Zhang Luyao;Li Ran;Zhang Nan;Liu Shan;Yang Xin;Wang Yue;Zhao Ying;Meng Xiangbao;Zhu Wei-Guo |
| 17 | Histone H1 acetylation at lysine 85 regulates chromatin condensation and genome stability upon DNA damage | 期刊论文 | Li Yinglu;Li Zhiming;Dong Liping;Tang Ming;Zhang Ping;Zhang Chaohua;Cao Ziyang;Zhu Qian;Chen Yongcan;Wang Hui;Wang Tianzhuo;Lv Danyu;Wang Lina;Zhao Ying;Yang Yang;Wang Haiying;Zhang Hongquan;Roeder Robert G.;Zhu Wei-Guo |
| 18 | 基于核磁共振氢谱的LSD1的活性检测方法及其应用 | 专利 | 文赫;朱卫国;李晓帆;田媛;王慧 |
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