miR-21-5p及miR-21-3p共调控在创伤性血脑屏障损伤修复中的作用及机制研究

81501055
2015
H0910.神经损伤、修复与再生
葛歆瞳
青年科学基金项目
讲师
天津医科大学
18万元
血管生成因子;miR-21-3p;miR-21-5p;颅脑创伤;血脑屏障
2016-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Long-term kinetics of immunologic components and neurological deficits in rats following repetitive mild traumatic brain injury 期刊论文 Bai Ruojing;Gao Huabin;Han Zhaoli;Ge Xintong;Huang Shan;Chen Fanglian;Lei Ping
2 The pathological role of NLRs and AIM2 inflammasome-mediated pyroptosis in damaged blood-brain barrier after traumatic brain injury 会议论文 葛歆瞳;李文竹;雷平;张建宁
3 Increased miR-21-3p in injured brain microvascular endothelial cells following traumatic brain injury aggravates blood-brain barrier damage by promoting cellular apoptosis and inflammation through targeting MAT2B 期刊论文 Ge Xintong;Li Wenzhu;Huang Shan;Yin Zhenyu;Yang Mengchen;Han Zhenying;Han Zhaoli;Chen Fanglian;Wang Haichen;Lei Ping;Zhang Jianning
4 The pathological role of NLRs and AIM2 inflammasome-mediated pyroptosis in damaged blood-brain barrier after traumatic brain injury 期刊论文 Ge Xintong;Li Wenzhu;Huang Shan;Yin Zhenyu;Xu Xin;Chen Fanglian;Kong Xiaodong;Wang Haichen;Zhang Jianning;Lei Ping
5 A novel repetitive mild traumatic brain injury mouse model for chronic traumatic encephalopathy research 会议论文 葛歆瞳;于金文;王增光;张建宁;雷平
6 间歇低氧导致海马miR-26b上调表达与神经元凋亡机制研究 期刊论文 高华斌;黄山;白若靖;韩召利;葛歆瞳;陈芳莲;雷平
7 大鼠反复轻度脑创伤后外周血中T细胞亚群的变化 期刊论文 白若靖;高华斌;韩召利;黄山;葛歆瞳;陈芳莲;雷平
8 反复轻度颅脑损伤大鼠动物模型的建立 期刊论文 高华斌;韩召利;黄山;白若靖;葛歆瞳;陈芳莲;雷平
9 Intermittent hypoxia caused cognitive dysfunction relate to mirnas dysregulation in hippocampus 期刊论文 Gao Huabin;Han Zhaoli;Huang Shan;Bai Ruojing;Ge Xintong;Chen Fanglian;Lei Ping
10 The accumulation of brain injury leads to severe neuropathological and neurobehavioral changes after repetitive mild traumatic brain injury. 期刊论文 Gao Huabin;Han Zhaoli;Bai Ruojing;Huang Shan;Ge Xintong;Chen Fanglian;Lei Ping
11 Flow Cytometric Characterization of T Cell Subsets and Microglia After Repetitive Mild Traumatic Brain Injury in Rats 期刊论文 Bai Ruojing;Gao Huabin;Han Zhaoli;Huang Shan;Ge Xintong;Chen Fanglian;Lei Ping
12 M2型小胶质细胞经损伤脑组织处理后其外泌体的miRNA芯片测序及生物信息学分析 会议论文 葛歆瞳;黄山;于金文;韩召利;殷振宇;陈芳莲;雷平;张建宁
13 神经重症(NICU)患者感染诊治:美国临床神经医学手册(2017-2018)与我国专家共识(2017)的对比与解读 期刊论文 葛歆瞳;Daniel T. Laskowitz;江荣才;张建宁
14 A novel repetitive mild traumatic brain injury mouse model for chronic traumatic encephalopathy research 期刊论文 Ge Xintong;Yu Jinwen;Huang Shan;Yin Zhenyu;Han Zhaoli;Chen Fanglian;Wang Zengguang;Zhang Jianning;Lei Ping
15 miR-21-5p alleviates leakage of injured brain microvascular endothelial barrier in vitro through suppressing inflammation and apoptosis 会议论文 葛歆瞳;黄山;韩召利;陈芳莲;雷平;张建宁
16 Increased miR-124-3p in microglial exosomes following traumatic brain injury inhibits neuronal inflammation and contributes to neurite outgrowth via their transfer into neurons 期刊论文 Huang Shan;Ge Xintong;Yu Jinwen;Han Zhaoli;Yin Zhenyu;Li Ying;Chen Fanglian;Wang Haichen;Zhang Jianning;Lei Ping
17 小胶质细胞表型在反复轻度脑创伤模型大鼠中的变化研究 期刊论文 白若靖;高华斌;韩召利;黄山;葛歆瞳;陈芳莲;雷平
18 microRNAs调控小胶质细胞极化在神经炎症中的作用 期刊论文 白若靖;高华斌;韩召利;黄山;葛歆瞳;陈芳莲;雷平;张建宁
19 miR-21-5p alleviates leakage of injured brain microvascular endothelial barrier in vitro through suppressing inflammation and apoptosis. 期刊论文 Ge Xintong;Huang Shan;Gao Huabin;Han Zhaoli;Chen Fanglian;Zhang Shishuang;Wang Zengguang;Kang Chunsheng;Jiang Rongcai;Yue Shuyuan;Lei Ping;Zhang Jianning
20 M2型小胶质细胞外泌体通过抑制颅脑创伤后免疫炎症反应改善认知功能预后的作用及机制研究 会议论文 葛歆瞳;黄山;殷振宇;韩召利;于金文;陈芳莲;雷平;张建宁
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