NLRP3炎性小体在高血压的血管平滑肌细胞表型转化与血管重构中的机制与干预靶点

31571167
2015
C1101.循环与血液生理
朱国庆
面上项目
教授
南京医科大学
63万元
血管平滑肌细胞;表型转化;炎性小体;血管重构;高血压
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
查看更多信息请先登录或注册
查看更多信息请先登录或注册
查看更多信息请先登录或注册
重置
序号 标题 类型 作者
1 BCL6抑制自发性高血压大鼠肾脏NLRP3炎性小体激活和炎症 会议论文 陈丹;熊晓青;臧英豪;佟影;周兵;陈琪;李跃华;高兴亚;康玉明;朱国庆
2 BCL6 attenuates renal inflammation via negative regulation of NLRP3 transcription. 期刊论文 Chen Dan;Xiong Xiao-Qing;Zang Ying-Hao;Tong Ying;Zhou Bing;Chen Qi;Li Yue-Hua;Gao Xing-Ya;Kang Yu-Ming;Zhu Guo-Qing
3 FNDC5抑制SHR血管外膜成纤维细胞的NLRP3炎性小体激活和表型转换 会议论文 凌莉;陈丹;佟影;臧英豪;任兴胜;周红;戚晓红;陈琪;李跃华;康玉明;朱国庆
4 Exosome-mediated Transfer of Angiotensin Converting Enzyme from Adventitial Fibroblasts of SHR Promotes VSMC Migration 会议论文 佟影;朱国庆
5 FNDC5 attenuates adipose tissue inflammation and insulin resistance via AMPK-mediated macrophage polarization in obesity. 期刊论文 Xiong Xiao-Qing;Geng Zhi;Zhou Bing;Zhang Feng;Han Ying;Zhou Ye-Bo;Wang Jue-Jin;Gao Xing-Ya;Chen Qi;Li Yue-Hua;Kang Yu-Ming;Zhu Guo-Qing
6 NLRP3 inflammasome activation and vascular remodeling in Hypertension 会议论文 朱国庆
7 Silencing salusin-beta attenuates cardiovascular remodeling and hypertension in spontaneously hypertensive rats. 期刊论文 Ren Xing-Sheng;Ling Li;Zhou Bing;Han Ying;Zhou Ye-Bo;Chen Qi;Li Yue-Hua;Kang Yu-Ming;Zhu Guo-Qing
8 NLRP3 Gene Deletion Attenuates Angiotensin II-Induced Phenotypic Transformation of Vascular Smooth Muscle Cells and Vascular Remodeling. 期刊论文 Xing-Sheng Ren;Ying Tong;Li Ling;Dan Chen;Hai-Jian Sun;Hong Zhou;Xiao-Hong Qi;Qi Chen;Yue-Hua Li;Yu-Ming Kang;Guo-Qing Zhu
9 MiR155-5p in adventitial fibroblasts-derived extracellular vesicles inhibits vascular smooth muscle cell proliferation via suppressing angiotensin-converting enzyme expression. 期刊论文 Ren Xing-Sheng;Tong Ying;Qiu Yun;Ye Chao;Wu Nan;Xiong Xiao-Qing;Wang Jue-Jin;Han Ying;Zhou Ye-Bo;Zhang Feng;Sun Hai-Jian;Gao Xing-Ya;Chen Qi;Li Yue-Hua;Kang Yu-Ming;Zhu Guo-Qing
10 Salusin-beta contributes to oxidative stress and inflammation in diabetic cardiomyopathy. 期刊论文 Zhao Ming-Xia;Zhou Bing;Ling Li;Xiong Xiao-Qing;Zhang Feng;Chen Qi;Li Yue-Hua;Kang Yu-Ming;Zhu Guo-Qing
11 Salusin在心血管病的发病机制中的重要作用 会议论文 朱国庆
12 Crosstalk between brain and adipose tissues in Obesity and Hypertension 会议论文 朱国庆
13 Salusin-b在糖尿病心肌病的心肌炎症和氧化应激中作用与机制 会议论文 赵明霞;朱国庆
14 NLRP3 inflammasome activation in hypertension 会议论文 Guo-Qing Zhu
15 Curcumin attenuates migration of vascular smooth muscle cells via inhibiting NF kappa B-mediated NLRP3 expression in spontaneously hypertensive rats 期刊论文 Han Ying;Sun Hai Jian;Tong Ying;Chen Yun Zhi;Ye Chao;Qiu Yun;Zhang Feng;Chen Ai Dong;Qi Xiao Hong;Chen Qi;Li Yue Hua;Kang Yu Ming;Zhu Guo Qing
16 Salusin-beta induces foam cell formation and monocyte adhesion in human vascular smooth muscle cells via miR155/NOX2/NFkappaB pathway. 期刊论文 Sun Hai-Jian;Zhao Ming-Xia;Liu Tong-Yan;Ren Xing-Sheng;Chen Qi;Li Yue-Hua;Kang Yu-Ming;Zhu Guo-Qing
17 FNDC5 attenuates obesity-induced adipose tissue inflammation via AMPK-mediated macrophage polarization 会议论文 Xiao-Qing Xiong;Zhi Geng;Bing Zhou;ZhangFeng;Ying Han;Ye-Bo Zhou;Jue-Jin Wang;Xing -Ya Gao;Qi Chen;Yue-Hua Li;Yu-Ming Kang;Guo-Qing Zhu
18 NLRP3基因敲除减轻AngII诱导的VSMC表型转化和血管重构 会议论文 任兴胜;佟影;凌莉;陈丹;孙海建;周红;戚晓红;陈琪;李跃华;康玉明;朱国庆
19 干涉salusin-β基因减轻自发性高血压大鼠的高血压和血管重构 会议论文 任兴胜;赵明霞;熊晓青;韩莹;周业波;朱国庆
20 FNDC5 Alleviates Hepatosteatosis by Restoring AMPK/mTOR-Mediated Autophagy, Fatty Acid Oxidation and Lipogenesis in Mice. 期刊论文 Liu Tong-Yan;Xiong Xiao-Qing;Ren Xing-Sheng;Zhao Ming-Xia;Shi Chang-Xiang;Wang Jue-Jin;Zhou Ye-Bo;Zhang Feng;Han Ying;Gao Xing-Ya;Chen Qi;Li Yue-Hua;Kang Yu-Ming;Zhu Guo-Qing
21 发明专利:鸢尾素在制备抗糖尿病药物中的应用 专利 朱国庆;熊晓青;刘桐言
22 Salusin-b在血管平滑肌细胞迁移和血管内膜增生中的作用与机制 会议论文 朱国庆
23 Salusin-beta Promotes Vascular Smooth Muscle Cell Migration and Intimal Hyperplasia After Vascular Injury via ROS/NFkappaB/MMP-9 Pathway. 期刊论文 Sun Hai-Jian;Zhao Ming-Xia;Ren Xing-Sheng;Liu Tong-Yan;Chen Qi;Li Yue-Hua;Kang Yu-Ming;Wang Jue-Jin;Zhu Guo-Qing
24 Fibronectin type III domain containing 5 attenuates NLRP3 inflammasome activation and phenotypic transformation of adventitial fibroblasts in spontaneously hypertensive rats. 期刊论文 Ling Li;Chen Dan;Tong Ying;Zang Ying-Hao;Ren Xing-Sheng;Zhou Hong;Qi Xiao-Hong;Chen Qi;Li Yue-Hua;Kang Yu-Ming;Zhu Guo-Qing
25 Exosome-Mediated Transfer of ACE (Angiotensin-Converting Enzyme) From Adventitial Fibroblasts of Spontaneously Hypertensive Rats Promotes Vascular Smooth Muscle Cell Migration. 期刊论文 Tong Ying;Ye Chao;Ren Xing-Sheng;Qiu Yun;Zang Ying-Hao;Xiong Xiao-Qing;Wang Jue-Jin;Chen Qi;Li Yue-Hua;Kang Yu-Ming;Zhu Guo-Qing
26 江苏省科学技术奖: 高血压的交感神经激活机制与干预靶点的研究 奖励 朱国庆;占伊扬;周业波;韩莹;陈琪;高兴亚;熊晓青
27 Exosomes from vascular fibroblast in proliferation and migration of vascular smooth muscle cells 会议论文 Guo-Qing Zhu
28 Crosstalk between adipose tissues and brain in obesity and hypertension 会议论文 朱国庆
29 Silencing salusin-βattenuates hypertension and cardiovascular remodeling in spontaneouslyhypertensive rats 会议论文 朱国庆
30 NLRP3 inflammasome activation contributes to VSMC phenotypic transformation and proliferation in hypertension. 期刊论文 Sun Hai-Jian;Ren Xing-Sheng;Xiong Xiao-Qing;Chen Yun-Zhi;Zhao Ming-Xia;Wang Jue-Jin;Zhou Ye-Bo;Han Ying;Chen Qi;Li Yue-Hua;Kang Yu-Ming;Zhu Guo-Qing
31 MiR155-5p in adventitial fibroblasts-derived extracellular vesicles inhibits vascular smooth muscle cell proliferation via suppressing angiotensin-converting enzyme expression 会议论文 朱国庆
32 BCL6 Attenuates Proliferation and Oxidative Stress of Vascular Smooth Muscle Cells in Hypertension 期刊论文 Chen Dan;Zang Ying Hao;Qiu Yun;Zhang Feng;Chen Ai Dong;Wang Jue Jin;Chen Qi;Li Yue Hua;Kang Yu Ming;Zhu Guo Qing
33 江苏省科学技术奖: 高血压的交感神经激活机制与干预靶点的研究 奖励 朱国庆;占伊扬;周业波;韩莹;陈琪;高兴亚;熊晓青
34 发明专利:鸢尾素在制备抗糖尿病药物中的应用 专利 朱国庆;熊晓青;刘桐言
查看更多信息请先登录或注册

相关项目

趋势报告

经验分享