海马调控恐惧记忆消退的神经及分子机制
31530091
2015
C0906.认知神经生物学
朱东亚
重点项目
教授
南京医科大学
284万元
背景关联恐惧;海马;神经环路;恐惧记忆;消除
2016-01-01到2020-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | (+)-Borneol is neuroprotective against permanent cerebral ischemia in rats by suppressing production of proinflammatory cytokines | 期刊论文 | Lei Chang;Chun-Yu Yin;Hai-Yin Wu;Bin-Bin Tian;Yan Zhu;Chun-Xia Luo;Dong-Ya Zhu |
| 2 | 一种动物饮水检测装置和动物行为检测组件 | 专利 | 周其冈;尹春雨;朱东亚;韩峰;姜志欣;齐一泽;夏天;杨君言 |
| 3 | 一类N-苄基取代的氨基水杨酸与4-氨基丁酸的酰胺衍生物及其药物用途 | 专利 | 朱东亚;李飞;戴鹏;陈云;陈明路;赵婷;李婷;沈盈盈;李俊 |
| 4 | nNOS-CAPON interaction mediates amyloid-β-induced neurotoxicity, especially in the early stages | 期刊论文 | Yu Zhang;Zhu Zhu;Hai-Ying Liang;Lin Zhang;Qi-Gang Zhou;Huan-Yu Ni;Chun-Xia Luo;Dong-Ya Zhu |
| 5 | ( )-Borneol suppresses conditioned fear recall and anxiety-like behaviors in mice | 期刊论文 | Cao Bo;Ni Huan Yu;Li Jun;Zhou Ying;Bian Xin Lan;Tao Yan;Cai Cheng Yun;Qin Cheng;Wu Hai Yin;Chang Lei;Luo Chun Xia;Zhu Dong Ya |
| 6 | Opening a New Time Window for Treatment of Stroke by Targeting HDAC2 | 期刊论文 | Lin Yu-Hui;Dong Jian;Tang Ying;Ni Huan-Yu;Zhang Yu;Su Ping;Liang Hai-Ying;Yao Meng-Cheng;Yuan Hong-Jin;Wang Dong-Liang;Chang Lei;Wu Hai-Yin;Luo Chun-Xia;Zhu Dong-Ya |
| 7 | Reactivation of Tert in the medial prefrontal cortex and hippocampus rescues aggression and depression of Tert(-/-) mice | 期刊论文 | Zhou Qi-Gang;Wu Hai-Yin;Zhou Hai-Hui;Liu Meng-Ying;Lee H-W;Liu X;Devkota S;Ro EJ;Zhu Dong-Ya;Suh H |
| 8 | Anterior Cingulate Cortex to Ventral Hippocampus Circuit Mediates Contextual Fear Generalization | 期刊论文 | Bian Xin Lan;Qin Cheng;Cai Cheng Yun;Zhou Ying;Tao Yan;Lin Yu Hui;Wu Hai Yin;Chang Lei;Luo Chun Xia;Zhu Dong Ya |
| 9 | rolonged Use of NMDAR Antagonist Develops Analgesic Tolerance in Neuropathic Pain via Nitric Oxide Reduction-Induced GABAergic Disinhibition | 期刊论文 | Jun Li;Lin Zhang;Chu Xu;Yu-Hui Lin;Yu Zhang;Hai-Yin Wu;Lei Chang;Ying-Dong Zhang;Chun-Xia Luo;Fei Li;Dong-Ya Zhu |
| 10 | nNOS-CAPON blockers produce anxiolytic effects by promoting synaptogenesis in chronic stress-induced animal models of anxiety | 期刊论文 | Li-Juan Zhu;Hu-Jiang Shi;Lei Chang;Cheng Cheng Zhang;Meng Si;Na Li;Dong-Ya Zhu |
| 11 | N-BENZYLANILINE DERIVATIVE AND USES | 专利 | 朱东亚;李飞;罗春霞 |
| 12 | N-BENZYLANILINE DERIVATIVE AND USES | 专利 | 朱东亚;李飞;罗春霞 |
| 13 | CREB-mediated synaptogenesis and neurogenesis is crucial for the role of 5-HT1a receptors in modulating anxiety behaviors | 期刊论文 | Zhang Jing;Cai Cheng-Yun;Wu Hai-Yin;Zhu Li-Juan;Luo Chun-Xia;Zhu Dong-Ya |
| 14 | Neuroprotection of taurine against reactive oxygen species is associated with inhibiting NADPH oxidases | 期刊论文 | Han Zhou;Gao Li-Yan;Lin Yu-Hui;Chang Lei;Wu Hai-Yin;Luo Chun-Xia;Zhu Dong-Ya |
| 15 | HDAC2 (Histone deacetylase 2): A critical factor in environmental enrichment-mediated stroke recovery | 期刊论文 | Yu‐Hui Lin;Meng‐Cheng Yao;Hai-Yiin Wu;Jian Dong;Huan-Yu Ni;Xiao-Lin Kou;Lei Chang;Chun-Xia Luo;Dong-Ya Zhu |
| 16 | PSD-95-nNOS Coupling Regulates Contextual Fear Extinction in the Dorsal CA3 | 期刊论文 | Cai Cheng Yun;Chen Chen;Zhou Ying;Han Zhou;Qin Cheng;Cao Bo;Tao Yan;Bian Xin Lan;Lin Yu Hui;Chang Lei;Wu Hai Yin;Luo Chun Xia;Zhu Dong Ya |
| 17 | Uncoupling nNOS-PSD-95 in the ACC can inhibit contextual fear generalization | 期刊论文 | Qin Cheng;Bian Xin Lan;Cai Cheng Yun;Chen Chen;Zhou Ying;Lin Yu Hui;Tao Yan;Wu Hai Yin;Chang Lei;Luo Chun Xia;Zhu Dong Ya |
| 18 | nNOS-expressing neurons in the vmPFC transform pPVT-derived chronic pain signals into anxiety behaviors | 期刊论文 | Hai-Ying Liang;Zhi-Jin Chen;Hui Xiao;Yu-Hui Lin;Ying-Yi Hu;Lei Chang;Hai-Yin Wu;Peng Wang;Wei Lu;Dong-Ya Zhu;Chun-Xia Luo |
| 19 | Inhibiting Histone Deacetylase 2 (HDAC2) Promotes Functional Recovery From Stroke | 期刊论文 | Tang Y;Lin YH;Ni HY;Dong J;Yuan HJ;Zhang Y;Liang HY;Yao MC;Zhou QG;Wu HY;Chang L;Luo CX;Zhu DY |
| 20 | Dissociating nNOS (Neuronal NO Synthase)-CAPON (Carboxy-Terminal Postsynaptic Density-95/Discs Large/Zona Occludens-1 Ligand of nNOS) Interaction Promotes Functional Recovery After Stroke via Enhanced Structural Neuroplasticity | 期刊论文 | Ni Huan Yu;Song Yi Xuan;Lin Yu Hui;Cao Bo;Wang Dong Liang;Zhang Yu;Dong Jian;Liang Hai Ying;Xu Ke;Li Ting You;Chang Lei;Wu Hai Yin;Luo Chun Xia;Zhu Dong Ya |
| 21 | Sucrose preference test for measurement of stress-induced anhedonia in mice | 期刊论文 | Meng-Ying Liu;Chun-Yu Yin;Li-Juan Zhu;Xian-Hui Zhu;Chu Xu;Chun-Xia Luo;Hong-Shan Chen;Dong-Ya Zhu;Qi-Gang Zhou |
| 22 | Disrupting nNOS-PSD-95 coupling in the hippocampal dentate gyrus promotes extinction memory retrieval | 期刊论文 | Li Jun;Han Zhou;Cao Bo;Cai Cheng-Yun;Lin Yu-Hui;Li Fei;Wu Hai-Ying;Chang Lei;Luo Chun-Xia;Zhu Dong-Ya |
| 23 | 抑郁症发病新机理及抗抑郁药新靶点的研究 | 奖励 | 高天明;朱东亚;曹鹏;朱心红;曹雄 |
| 24 | Dissociation of nNOS from PSD-95 promotes functional recovery after cerebral ischaemia in mice through reducing excessive tonic GABA release from reactive astrocytes | 期刊论文 | Lin YH;Liang HY;Xu K;Ni HY;Dong J;Xiao H;Chang L;Wu HY;Li F;Zhu DY;Luo CX |
| 25 | ZL006 promotes migration and differentiation of transplanted neural stem cells in male rats after stroke | 期刊论文 | Wang DL;Qian XD;Lin YH;Tian BB;Liang HY;Chang L;Wu HY;Zhu DY;Luo CX |
| 26 | 重大神经精神疾病的药物新靶标研究 | 奖励 | 朱东亚;罗春霞;周其冈;李飞;厉廷有;胡瑶;张晶;吴海银;常磊 |
| 27 | Hippocampal TERT Regulates Spatial Memory Formation through Modulation of Neural Development | 期刊论文 | Zhou Qi Gang;Liu Meng Ying;Lee Han Woong;Ishikawa Fuyuki;Devkota Sushil;Shen Xin Ru;Jin Xin;Wu Hai Yin;Liu Zhigang;Liu Xiao;Jin Xun;Zhou Hai Hui;Ro Eun Jeoung;Zhang Jing;Zhang Yu;Lin Yu Hui;Suh Hoonkyo;Zhu Dong Ya |
| 28 | Uncoupling nNOS-PSD-95 in mPFC inhibits morphine priming-induced reinstatement after extinction training | 期刊论文 | Xiao-Lin Kou;Yan Tao;Jia-Yun Xian;Yu-Hui Lin;Cheng-Yun Cai;Hai-Yin Wu;Lei Chang;Dong-Ya Zhu |
| 29 | 2-Methyl-5H-benzo[d]pyrazolo[5,1-b][1,3]oxazin-5-imine, an edaravone analog, exerts neuroprotective effects against acute ischemic injury via inhibiting oxidative stress | 期刊论文 | Huan-Yu Ni;Yi-Xuan Song;Hai-Yin Wu;Lei Chang;Chun-Xia Luo;Dong-Ya Zhu |
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