亚细胞结构内蛋白质相互作用的质谱分析方法研究及其在探索肿瘤转移机制中的应用
21575103
2015
B0403.谱学方法与理论
陈瑞冰
面上项目
教授
天津医科大学
65万元
肿瘤转移;蛋白质相互作用;定量蛋白质组学;液相色谱质谱;免疫沉淀结合质谱分析
2016-01-01到2019-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Ectopic overexpression of filamin C scaffolds MEK1/2 and ERK1/2 to promote the progression of human hepatocellular carcinoma | 期刊论文 | Yang Baicai;Liu Yun;Zhao Jie;Hei Kaiwen;Zhuang Hao;Li Qiang;Wei Wen;Chen Ruibing;Zhang Ning;Li Yongmei |
| 2 | Multiomics Integration Reveals the Landscape of Prometastasis Metabolism in Hepatocellular Carcinoma | 期刊论文 | Li Yongmei;Zhuang Hao;Zhang Xinran;Li Yuan;Liu Yun;Yi Xianfu;Qin Guoxuan;Wei Wen;Chen Ruibing |
| 3 | Quantitative Proteomics Implicates Rictor/mTORC2 in Cell Adhesion | 期刊论文 | Hao Wang;Xianfeng Shao;Qian He;Chunqing Wang;Linhuan Xia;Dan Yue;Guoxuan Qin;Chenxi Jia;Ruibing Chen |
| 4 | Demethylation-Induced Overexpression of Shc3 Drives c-Raf-Independent Activation of MEK/ERK in HCC | 期刊论文 | Liu Yun;Zhang Xinran;Yang Baicai;Zhuang Hao;Guo Hua;Wei Wen;Li Yuan;Chen Ruibing;Li Yongmei;Zhang Ning |
| 5 | The Role of YB1 in Renal Cell Carcinoma Cell Adhesion | 期刊论文 | Yong Wang;Jing Su;Donghe Fu;Yiting Wang;Yajing Chen;Ruibing Chen;Guoxuan Qin;Jing Zuo;Dan Yue |
| 6 | Identification of a novel mitochondrial interacting protein of C1QBP using subcellular fractionation coupled with CoIP-MS | 期刊论文 | Chen Ruibing;Xiao Mingming;Gao Huajun;Chen Yajing;Li Yongmei;Liu Yunde;Zhang Ning |
| 7 | Profiling the interactome of protein kinase C zeta by proteomics and bioinformatics | 期刊论文 | Hou Chunyu;Li Yuan;Liu Huiqin;Dang Mengjiao;Qin Guoxuan;Zhang Ning;Chen Ruibing |
| 8 | 结合亲和质谱与生物信息学分析构建TP53BP1的蛋白相互作用网络 | 期刊论文 | 王浩;王春晴;陈瑞冰 |
| 9 | Clinical proteomics: a driving force for cancer therapeutic target discovery and precision medicine. | 期刊论文 | Wang H;Jiang N;Zhang Y;Chen R |
| 10 | CD4 T cells promote renal cell carcinoma proliferation via modulating YBX1 | 期刊论文 | Wang Yong;Wang Yiting;Xu Liang;Lu Xianqi;Fu Donghe;Su Jing;Geng Hua;Qin Guoxuan;Chen Ruibing;Quan Changyi;Niu Yuanjie;Yue Dan |
| 11 | Quantitative proteomics reveals that long non-coding RNA MALAT1 interacts with DBC1 to regulate p53 acetylation | 期刊论文 | Chen Ruibing;Liu Yun;Zhuang Hao;Yang Baicai;Hei Kaiwen;Xiao Mingming;Hou Chunyu;Gao Huajun;Zhang Xinran;Jia Chenxi;Li Lingjun;Li Yongmei;Zhang Ning |
| 12 | Deciphering the protein protein interaction network regulating hepatocellular carcinoma metastasis | 期刊论文 | Qin Guoxuan;Dang Mengjiao;Gao Huajun;Wang Hao;Luo Fengting;Chen Ruibing |
| 13 | Downregulation of glycine decarboxylase enhanced cofilin-mediated migration in hepatocellular carcinoma cells | 期刊论文 | Zhuang Hao;Li Qiang;Zhang Xinran;Ma Xuda;Wang Zun;Liu Yun;Yi Xianfu;Chen Ruibing;Han Feng;Zhang Ning;Li Yongmei |
| 14 | Interactome analysis reveals MALAT1 binding with DBC1-author's reply | 期刊论文 | Chen Ruibing;Liu Yun;Zhuang Hao;Zhang Xinran;Shao Xiaowen;Dang Yamei;Wu Fei;Li Yongmei;Zhang Ning |
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