DNA羟甲基化酶TET2调控Th17细胞分化及其在系统性红斑狼疮发病中的作用
81373205
2013
H1107.自身免疫性疾病
陆前进
面上项目
教授
中南大学
70万元
DNA甲基化;TET2;系统性红斑狼疮;Th17细胞;DNA羟甲基化
2014-01-01到2017-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 红斑狼疮诊治策略及其关键技术的创新与应用 | 奖励 | 陆前进;赵明;戴勇;张建中;肖嵘;吴海竞;龙海;廖洁月;李亚萍;汤冬娥 |
| 2 | Critical Link Between Epigenetics and Transcription Factors in the Induction of Autoimmunity: a Comprehensive Review | 期刊论文 | Wu Haijing;Zhao Ming;Yoshimura Akihiko;Chang Christopher;Lu Qianjin |
| 3 | Epigenetics in the treatment of systemic lupus erythematosus: Potential clinical application | 期刊论文 | Guo Yu;Sawalha Amr H.;Lu Qianjin |
| 4 | Cell-based therapies for systemic lupus erythematosus | 期刊论文 | Liao Jieyue;Chang Christopher;Wu Haijing;Lu Qianjin |
| 5 | The role of icaritin in regulating Foxp3/IL17a balance in systemic lupus erythematosus and its effects on the treatment of MRL/lpr mice | 期刊论文 | Liao Jieyue;Liu Yu;Wu Haijing;Zhao Ming;Tan Yixin;Li Duo;Long Hai;Dai Yong;Yung Susan;Chan Tak-Mao;Lu Qianjin |
| 6 | The key culprit in the pathogenesis of systemic lupus erythematosus: Aberrant DNA methylation | 期刊论文 | Wu Haijing;Zhao Ming;Tan Lina;Lu Qianjin |
| 7 | Unmet Needs in Autoimmunity and Potential New Tools | 期刊论文 | Lu Qianjin |
| 8 | 自身免疫性疾病发生发展的分子机制 | 奖励 | 陆前进;陈德茂;赵明;肖嵘;张鹏;苏玉文;张庆;梁云生;赵莎;丁澍;廉晓日;刘倩;龙海 |
| 9 | Mycophenolic acid upregulates miR-142-3P/5P and miR-146a in lupus CD4(+)T cells | 期刊论文 | Tang Q.;Yang Y.;Zhao M.;Liang G.;Wu H.;Liu Q.;Xie Y.;Li D.;Dai Y.;Yung S.;Chan T. M.;Lu Q. |
| 10 | Increased 5-hydroxymethylcytosine in CD4(+) T cells in systemic lupus erythematosus | 期刊论文 | Zhao Ming;Wang Jing;Liao Wei;Li Duo;Li Mengying;Wu Haijing;Zhang Yiqun;Gershwin M. Eric;Lu Qianjin |
| 11 | TLR2 and TLR4 in Autoimmune Diseases: a Comprehensive Review | 期刊论文 | Liu Yu;Yin Heng;Zhao Ming;Lu Qianjin |
| 12 | DNA methylation and mRNA and microRNA expression of SLE CD4+T cells correlate with disease phenotype | 期刊论文 | Zhao Ming;Liu Siyang;Luo Shuangyan;Wu Honglong;Tang Meini;Cheng Wenjing;Zhang Qing;Zhang Peng;Yu Xinhai;Xia Yudong;Yi Na;Gao Fei;Wang Li;Yung Susan;Chan Tak Mao;Sawalha Amr H.;Richardson Bruce;Gershwin M. Eric;Li Ning;Lu Qianjin |
| 13 | TET Family of Dioxygenases: Crucial Roles and Underlying Mechanisms | 期刊论文 | Li Duo;Guo Bin;Wu Haijing;Tan Lina;Lu Qianjin |
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