1Kb分辨率Hi-C数据分析框架搭建及其在人干细胞肝向分化研究中的应用
31871343
2018
C0608.生物数据资源与分析方法
陈阳
面上项目
研究员
清华大学
60万元
1Kb分辨率;Hi-C;新一代测序分析;人;染色质构象
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | CASPIAN: A Method to Identify Chromatin Topological Associated Domains based on Spatial Density Cluster | 期刊论文 | Haiyan Gong;Yi Yang;Xiaotong Zhang;Minghong Li;Sichen Zhang;Yang Chen |
| 2 | MINE is a method for detecting spatial density of regulatory chromatin interactions based on a MultI-modal NEtwork | 期刊论文 | Haiyan Gong;Minghong Li;Mengdie Ji;Xiaotong Zhang;Zan Yuan;Sichen Zhang;Yi Yang;Chun Li;Yang Chen |
| 3 | Spatial density of open chromatin: an effective metric for the functional characterization of topologically associated domains | 期刊论文 | Jiang Shuai;Li Hao;Hong Hao;Du Guifang;Huang Xin;Sun Yu;Wang Junting;Tao Huan;Xu Kang;Li Cheng;Chen Yang;Chen Hebing;Bo Xiaochen |
| 4 | Enhanced expression of FCER1G predicts positive prognosis in multiple myeloma | 期刊论文 | Lin Fu;Zhiheng Cheng;Fen Dong;Liang Quan;Longzhen Cui;Yan Liu;Tiansheng Zeng;Wenhui Huang;Jinghong Chen;Ying Pang;Xu Ye;Guangsheng Wu;Tingting Qian;Yang Chen;Chaozeng Si |
| 5 | MyoD is a 3D genome structure organizer for muscle cell identity | 期刊论文 | Ruiting Wang;Fengling Chen;Qian Chen;Xin Wan;Minglei Shi;Antony K. Chen;Zhao Ma;Guohong Li;Min Wang;Yachen Ying;Qinyao Liu;Hu Li;Xu Zhang;Jinbiao Ma;Jiayun Zhong;Meihong Chen;Michael Q. Zhang;Yong Zhang;Yang Chen;Dahai Zhu |
| 6 | HiCDB :a sensitive and robust method for detecting contact domain boundaries. | 期刊论文 | Fengling Chen;Guipeng Li;Michael Q Zhang;Yang Chen |
| 7 | Multiomics metabolic and epigenetics regulatory network in cancer: A systems biology perspective | 期刊论文 | Xuezhu Wang;Yucheng Dong;Yongchang Zheng;Yang Chen |
| 8 | PhaSepDB: a database of liquid–liquid phase separation related proteins | 期刊论文 | Kaiqiang You;Qi Huang;Chunyu Yu;Boyan Shen;Cristoffer Sevilla;Minglei Shi;Henning Hermjakob;Yang Chen;Tingting Li |
| 9 | 一种染色质拓扑结构域边界的分析方法 | 专利 | 陈阳;陈凤玲;李贵鹏 |
| 10 | GTSE1, CDC20, PCNA, and MCM6 Synergistically Affect Regulations in Cell Cycle and Indicate Poor Prognosis in Liver Cancer | 期刊论文 | Yongchang Zheng;Yue Shi;Si Yu;Yuanyuan Han;Kai Kang;Haifeng Xu;Huajian Gu;Xinting Sang;Yang Chen;Jingyu Wang |
| 11 | Quantifying the phase separation property of chromatin-associated proteins under physiological conditions using an anti-1,6-hexanediol index | 期刊论文 | Shi Minglei;You Kaiqiang;Chen Taoyu;Hou Chao;Liang Zhengyu;Liu Mingwei;Wang Jifeng;Wei Taotao;Qin Jun;Chen Yang;Zhang Michael Q.;Li Tingting |
| 12 | 2021 年中国生物信息学十大进展:SEAM is a spatial single nuclear metabolomics method for dissecting tissue microenvironment | 奖励 | 张奇伟;张新荣;陈阳 |
| 13 | SEAM is a spatial single nuclear metabolomics method for dissecting tissue microenvironment | 期刊论文 | Zhiyuan Yuan;Qiming Zhou;Lesi Cai;Lin Pan;Weiliang Sun;Shiwei Qumu;Si Yu;Jiaxin Feng;Hansen Zhao;Yongchang Zheng;Minglei Shi;Shao Li;Yang Chen;Xinrong Zhang;Michael Q. Zhang |
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