长时程记忆的表观遗传学调节机制

31171008
2011
C0901.分子与细胞神经生物学
管吉松
面上项目
研究员
清华大学
78万元
表观遗传;学习记忆;选择性剪切;突触可塑性;基因表达调控
2012-01-01到2015-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Activity-dependent p25 generation regulates synaptic plasticity and Abeta-induced cognitive impairment. 期刊论文 Mungenast, Alison E|Guan, Ji-Song|Delalle, Ivana|Tsai, Li-Huei|
2 An epigenetic blockade of cognitive functions in the neurodegenerating brain 期刊论文 Joseph, Nadine|Haggarty, Stephen J.|Delalle, Ivana|Tsai, Li-Huei|
3 Kinetically selective inhibitors of histone deacetylase 2 (HDAC2) as cognition enhancers 期刊论文 Scolnick, E.|Haggarty, S. J.|Tsai, L. -H.|Holson, E. B.|
4 The role of epigenetic regulation in learning and memory 期刊论文 Guan J.-S.|Xie H.|Ding X.|
5 In Vivo imaging of immediate early gene expression reveals layer-specific memory traces in the mammalian brain 期刊论文 Youzhi Zhu|Xinlu Ding|Yuhao Yang|Ji-Song Guan|
6 针对DNA长片段靶标的锌指筛选体系 期刊论文 梁忱|白冰|高冠军|管吉松|
7 Crebinostat: A novel cognitive enhancer that inhibits histone deacetylase activity and modulates chromatin-mediated neuroplasticity 期刊论文 Mazitschek, Ralph|Schreiber, Stuart L.|Tsai, Li-Huei|Haggarty, Stephen J.|
8 3-Hydroxybutyrate methyl ester as a potential drug against Alzheimer's disease via mitochondria protection mechanism 期刊论文 Guan, Ji-Song|Chen, Jin-Chun|Wu, Qiong|Chen, Guo-Qiang|
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