Tet2-Blimp1调控Tfh细胞分化参与1型糖尿病发生的作用及机制
81873634
2018
H0701.内分泌系统免疫相关疾病
谢志国
面上项目
副研究员
中南大学
57万元
滤泡辅助T细胞;B淋巴细胞诱导成熟蛋白1;DNA羟甲基化酶Tet2;1型糖尿病;信号转导与转录激活因子5
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | The Role of Epigenetics in Type 1 Diabetes. | 期刊论文 | Zhiguo Xie;Christopher Chang;Gan Huang;Zhiguang Zhou |
| 2 | rs3806265 and rs4612666 of the NLRP3 Gene Are Associated With the Titer of Glutamic Acid Decarboxylase Antibody in Type 1 Diabetes | 期刊论文 | Xiaoxiao Sun;Linling Xu;Ying Xia;Shuoming Luo;Jian Lin;Yang Xiao;Gan Huang;Xia Li;Zhiguo Xie;Zhiguang Zhou |
| 3 | 自身免疫糖尿病的发病机制及其临床应用 | 奖励 | 周智广;李霞;向宇飞;肖扬;罗说明;王臻;谢志国;黄干;杨琳;俞海波;林健;邓超;郑沛林;金萍;刘玲娇 |
| 4 | Emerging Roles of Exosomes in T1DM | 期刊论文 | Haipeng Pang;Shuoming Luo;Yang Xiao;Ying Xia;Xia Li;Gan Huang;Zhiguo Xie;Zhiguang Zhou |
| 5 | The NLRP3 Inflammasome and Its Role in T1DM | 期刊论文 | Xiaoxiao Sun;Haipeng Pang;Jiaqi Li;Shuoming Luo;Gan Huang;Xia Li;Zhiguo Xie;Zhiguang Zhou |
| 6 | The Association of CTLA-4 rs231775 and rs3087243 Polymorphisms with Latent Autoimmune Diabetes in Adults: A Meta-Analysis | 期刊论文 | Haipeng Pang;Shuoming Luo;Gan Huang;Xia Li;Zhiguo Xie;Zhiguang Zhou |
| 7 | Role of Tet2 in Regulating Adaptive and Innate Immunity | 期刊论文 | Jiaqi Li;Lifang Li;Xiaoxiao Sun;Tuo Deng;Gan Huang;Xia Li;Zhiguo Xie;Zhiguang Zhou |
| 8 | Plasma-derived exosomal mRNA profiles associated with type 1 diabetes mellitus | 期刊论文 | Wenqi Fan;Haipeng Pang;Xiajie Shi;Jiaqi Li;Yimeng Wang;Shuoming Luo;Jian Lin;Haibo Yu;Yang Xiao;Xia Li;Gan Huang;Zhiguo Xie;Zhiguang Zhou |
| 9 | The Positivity Rate of IA-2A and ZnT8A in the Chinese Han Population With Type 1 Diabetes Mellitus: Association With rs1143627 and rs1143643 Polymorphisms in the IL1B Gene | 期刊论文 | Jiaqi Li;Xiaoxiao Sun;Shuoming Luo;Jian Lin;Yang Xiao;Haibo Yu;Gan Huang;Xia Li;Zhiguo Xie;Zhiguang Zhou |
| 10 | The m6A methylation profiles of immune cells in type 1 diabetes mellitus | 期刊论文 | Yimeng Wang;Linling Xu;Shuoming Luo;Xiaoxiao Sun;Jiaqi Li;Haipeng Pang;Jun Zhou;Yuemin Zhou;Xiajie Shi;Xia Li;Gan Huang;Zhiguo Xie;Zhiguang Zhou |
| 11 | Emerging roles of rare and low-frequency genetic variants in type 1 diabetes mellitus | 期刊论文 | Haipeng Pang;Ying Xia;Shuoming Luo;Gan Huang;Xia Li;Zhiguo Xie;Zhiguang Zhou |
| 12 | The polymorphism of the CARD8 inflammasome-related gene is associated with glutamic-acid-decarboxylase-antibody positivity in patients with type 1 diabetes mellitus | 期刊论文 | Haipeng Pang;Xiaoxiao Sun;Shuoming Luo;Jian Lin;Xiajie Shi;Yang Xiao;Gan Huang;Xia Li;Zhiguo Xie;Zhiguang Zhou |
| 13 | 1型糖尿病患者NLRC4基因外显子罕见变异的鉴定及其对基因功能的影响 | 期刊论文 | 许林凌;罗海荣;时夏捷;庞海鹏;李嘉琪;王祎梦;罗说明;林健;俞海波;肖扬;李霞;黄干;谢志国;周智广 |
| 14 | Characterization of lncRNA Profiles of Plasma-Derived Exosomes From Type 1 Diabetes Mellitus | 期刊论文 | Haipeng Pang;Wenqi Fan;Xiajie Shi;Jiaqi Li;Yimeng Wang;Shuoming Luo;Jian Lin;Gan Huang;Xia Li;Zhiguo Xie;Zhiguang Zhou |
| 15 | The association of HLA-DP loci with autoimmune diabetes in Chinese | 期刊论文 | Ying Xia;Xia Li;Gan Huang;Jian Lin;Shuoming Luo;Zhiguo Xie;Zhiguang Zhou |
| 16 | Polymorphisms of the NLRC4 Gene are Associated with the Onset Age, Positive Rate of GADA and 2-h Postprandial C-Peptide in Patients with Type 1 Diabetes | 期刊论文 | Linling Xu;Xiaoxiao Sun;Ying Xia;Shuoming Luo;Jian Lin;Yang Xiao;Yue Liu;Yanfei Wang;Gan Huang;Xia Li;Zhiguo Xie;Zhiguang Zhou |
| 17 | Polymorphisms in NLRP1 Gene Are Associated with Type 1 Diabetes | 期刊论文 | Xiaoxiao Sun;Ying Xia;Yue Liu;Yanfei Wang;Shuoming Luo;Jian Lin;Gan Huang;Xia Li;Zhiguo Xie;Zhiguang Zhou |
| 18 | NLRP2基因多态性与中国汉族人群1型糖尿病的关联研究 | 期刊论文 | 孙肖霄;夏影;许林凌;罗说明;林健;肖扬;李霞;黄干;谢志国;周智广 |
| 19 | Advances in Knowledge of Candidate Genes Acting at the Beta-Cell Level in the Pathogenesis of T1DM | 期刊论文 | Haipeng Pang;Shuoming Luo;Gan Huang;Ying Xia;Zhiguo Xie;Zhiguang Zhou |
| 20 | The missing heritability in type 1 diabetes | 期刊论文 | Haipeng Pang;Jian Lin;Shuoming Luo;Gan Huang;Xia Li;Zhiguo Xie;Zhiguang Zhou |
| 21 | The Emerging Role of m6A Modification in Regulating the Immune System and Autoimmune Diseases | 期刊论文 | Yimeng Wang;Lifang Li;Jiaqi Li;Bin Zhao;Gan Huang;Xia Li;Zhiguo Xie;Zhiguang Zhou |
| 22 | 黑色素瘤缺乏因子2基因rs2276405和rs2793845单核苷酸多态性与1型糖尿病的关联研究 | 期刊论文 | 孙肖霄;许林凌;夏影;罗说明;林健;肖扬;李霞;黄干;谢志国;周智广 |
| 23 | A new screening strategy and whole-exome sequencing for the early diagnosis of maturity-onset diabetes of the young | 期刊论文 | Liu Yue;Xie Zhiguo;Sun Xiaoxiao;Wang Yanfei;Xiao Yang;Luo Shuoming;Huang Gan;Li Xia;Xia Ying;Zhou Zhiguang |
| 24 | 1型糖尿病遗传学研究进展 | 期刊论文 | 孙肖霄;黄干;谢志国;周智广 |
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