心肌缺血/再灌注损伤新机制：USP7介导的心肌细胞凋亡和铁坏死

81872873
2018
H3502.心脑血管药物药理
彭军
面上项目
教授
中南大学
57万元
铁坏死;泛素特异性蛋白酶7;凋亡;心肌缺血/再灌注;转铁蛋白受体1
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Allopurinol attenuates oxidative injury in rat hearts suffered ischemia/reperfusion via suppressing the xanthine oxidase/vascular peroxidase 1 pathway 期刊论文 Yi-Shuai Zhang;Li-Qun Lu;Ya-Qian Jiang;Nian-Sheng Li;Xiu-Ju Luo;Jin-Wu Peng;Jun Peng
2 铁死亡诱导剂和抑制剂的研究进展 期刊论文 孙晟杰;涂画;唐励静;罗秀菊;彭军
3 Magnesium lithospermate B prevents phenotypic transformation of pulmonary arteries in rats with hypoxic pulmonary hypertension through suppression of NADPH oxidase 期刊论文 Tao Li;Xiu-Ju Luo;E-Li Wang;Nian-Sheng Li;Xiao-Jie Zhang;Feng-Lin Song;Jin-Fu Yang;Bin Liu;Jun Peng
4 Targeting the pathways of regulated necrosis: a potential strategy for alleviation of cardio-cerebrovascular injury 期刊论文 Li-Qun Lu;Jing Tian;Xiu-Ju Luo;Jun Peng
5 Natural compound methyl protodioscin protects rat brain from ischemia/reperfusion injury through regulation of Mul1/SOD2 pathway 期刊论文 Shu Guo;Yi-Yue Zhang;Jing-Jie Peng;Yue-Qi Li;Wei-Ning Liu;Meng-Xuan Tang;Xiao-Jie Zhang;Jie Yang;Jun Peng;Xiu-Ju Luo
6 Combination of ponatinib with deferoxamine synergistically mitigates ischemic heart injury via simultaneous prevention of necroptosis and ferroptosis 期刊论文 Hua Tu;Yuan-Jing Zhou;Li-Jing Tang;Xiao-Ming Xiong;Xiao-Jie Zhang;Sayed Ali Sheikh;Jie-Jie Zhang;Xiu-Ju Luo;Chuang Yuan;Jun Peng
7 Ferroptosis occurs in phase of reperfusion but not ischemia in rat heart following ischemia or ischemia/reperfusion 期刊论文 Li-Jing Tang;Xiu-Ju Luo;Hua Tu;Heng Chen;Xiao-Ming Xiong;Nian-Sheng Li;Jun Peng
8 Ubiquitin-specific protease 7 promotes ferroptosis via activation of the p53/TfR1 pathway in the rat hearts after ischemia/reperfusion 期刊论文 Li-Jing Tang;Yuan-Jing Zhou;Xiao-Ming Xiong;Nian-Sheng Li;Jie-Jie Zhang;Xiu-Ju Luo;Jun Peng
9 Ligustroflavone reduces necroptosis in rat brain after ischemic stroke through targeting RIPK1/RIPK3/MLKL pathway 期刊论文 Yi-Yue Zhang;Wei-Ning Liu;Yue-Qi Li;Xiao-Jie Zhang;Jie Yang;Xiu-Ju Luo;Jun Peng
10 Arctiin protects rat heart against ischemia/reperfusion injury via a mechanism involving reduction of necroptosis 期刊论文 Heng Chen;Li-Jing Tang;Hua Tu;Yuan-Jing Zhou;Nian-Sheng Li;Xiu-Ju Luo;Jun Peng
11 Upregulation of mitochondrial E3 ubiquitin ligase 1 in rat heart contributes to ischemia/reperfusion injury 期刊论文 Shi-Jing Wang;Heng Chen;Li-Jing Tang;Hua Tu;Bin Liu;Nian-Sheng Li;Xiu-Ju Luo;Jun Peng
12 Insights into the novel function of system Xc- in regulated cell death. 期刊论文 H Tu;L-J Tang;X-J Luo;K-L Ai;J Peng
13 Inhibition of Phosphoglycerate Mutase 5 Reduces Necroptosis in Rat Hearts Following Ischemia/Reperfusion Through Suppression of Dynamin-Related Protein 1 期刊论文 Lang She;Hua Tu;Yin-Zhuang Zhang;Li-Jing Tang;Nian-Sheng Li;Qi-Lin Ma;Bin Liu;Qingjie Li;Xiu-Ju Luo;Jun Peng
14 Polymyxin B Reduces Brain Injury in Ischemic Stroke Rat Through a Mechanism Involving Targeting ESCRT-III Machinery and RIPK1/RIPK3/MLKL Pathway 期刊论文 Jing Tian;Yi-Yue Zhang;Ya-Wei Peng;Bin Liu;Xiao-Jie Zhang;Zhong-Yang Hu;Chang-Ping Hu;Xiu-Ju Luo;Jun Peng
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