2,2-二取代-1,3-环己二酮的对映选择性去对称化反应研究及其在多环吲哚生物碱合成中的应用
21971140
2019
B0107.天然产物全合成
唐叶峰
面上项目
副教授
清华大学
65万元
串联反应;去对称;合成策略;天然产物合成;生物碱
2020-01-01到2023-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Biomimetic Diels–Alder Reactions in Natural Product Synthesis: A Personal Retrospect | 期刊论文 | Yefeng Tang;Jingchun Liu;Shuang Xi |
| 2 | Collective total syntheses of cytochalasans and merocytochalasans | 期刊论文 | Haoyu Zhang;Jingyang Zhang;Ruiyang Bao;Chong Tian;Yefeng Tang |
| 3 | Investigate Natural Product Indolmycin and the Synthetically Improved Analogue Toward Antimycobacterial Agents. | 期刊论文 | Yang Yuhong;Xu Yuanyuan;Yue Yuan;Wang Heng;Cui Yumeng;Pan Miaomiao;Zhang Xi;Zhang Lin;Li Haitao;Xu Min;Tang Yefeng;Chen Shawn |
| 4 | Tailored Synthesis of Skeletally Diverse Stemona Alkaloids through Chemoselective Dyotropic Rearrangements of β-Lactones | 期刊论文 | Guo Zhen;Bao Ruiyang;Li Yuanhe;Li Yunshan;Zhang Jingyang;Tang Yefeng |
| 5 | Chemical trigger-enabled bioconjugation reaction | 期刊论文 | Xie Fayang;Jia Xiangqian;Zhu Zhu;Wu Yunfei;Jiang Haolin;Yang Hongzhi;Cao Yu;Zhu Rui;Zhou Bing;Du Juanjuan;Tang Yefeng |
| 6 | Discovery of small-molecule activators of nicotinamide phosphoribosyltransferase (NAMPT) and their preclinical neuroprotective activity | 期刊论文 | Yao Hong;Liu Minghui;Wang Leibo;Zu Yumeng;Wu Chou;Li Chenyu;Zhang Ruoxi;Lu Haigen;Li Feifei;Xi Shuang;Chen Shuangquan;Gu Xuanyu;Liu Tianya;Cai Jie;Wang Shirong;Yang Maojun;Xing Guogang;Xiong Wei;Hua Lan;Tang Yefeng;Wang Gelin |
| 7 | Optimization of NAMPT activators to achieve invivo neuroprotective efficacy | 期刊论文 | Leibo Wang;Minghui Liu;Yumeng Zu;Hong Yao;Chou Wu;Ruoxi Zhang;Weinan Ma;Haigen Lu;Shuang Xi;Yang Liu;Lan Hua;Gelin Wang;Yefeng Tang |
| 8 | Strain-Driven Dyotropic Rearrangement: A Unified Ring-Expansion Approach to α-Methylene-γ-butyrolactones | 期刊论文 | Lei Xiaoqiang;Li Yuanhe;Lai Yang;Hu Shengkun;Qi Chen;Wang Gelin;Tang Yefeng |
| 9 | Enantioselective Total Synthesis of Dysiherbols A, C, and D | 期刊论文 | Shengkun Hu;Yefeng Tang |
| 10 | Elucidating the selectivity of dyotropic rearrangements of β-lactones: a computational survey | 期刊论文 | Jingyang Zhang;Yumiao Ma;Ke Qiu;Bo Li;Zhengwen Xue;Boxue Tian;Yefeng Tang |
| 11 | Facile access to spiro[4,5]decanes through oxidative dearomatization-induced ring expansion of cyclobutanes | 期刊论文 | Xi Shuang;Jingyang Zhang;Zhen Guo;Yumeng Zu;Yang Liu;Geling Wang;Yefeng Tang |
| 12 | Natural Product-Oriented Photo-Induced Denitrogenative Annulations of 1-Alkenylbenzotriazoles | 期刊论文 | Zhiguo Wang;Yi Chen;Zhen Dong;Yefeng tang |
| 13 | Total Synthesis of Carolacton and Demethylcarolactons with Potent Antiviral Activity | 期刊论文 | Haoyu Zhang;Bingsong Li;Hongzhi Yang;Ya Tan;Xu Tan;Yefeng Tang |
| 14 | Bridgehead Alkene-Enabled Strain-Driven Bioorthogonal Reaction | 期刊论文 | Fayang Xie;Haolin Jiang;Xiangqian Jia;Jingyang Zhang;Zhu Zhu;Juanjuan Du;Yefeng Tang |
| 15 | Photo-induced two-carbon ring expansion of N-alkenyl lactams and N-alkenyl/phenyl benzoazetinones. | 期刊论文 | Fayang Xie;Yin Chen;Yunshann Li;Zhiguo Wang;Jingyang Zhang;Yefeng Tang |
| 16 | Biomimetic Synthesis of Natural Products: A Journey To Learn, To Mimic, and To Be Better | 期刊论文 | Bao Ruiyang;Zhang Haoyu;Tang Yefeng |
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