Rac1/LncRNA-MEG3/FUNDC1调控线粒体自噬在糖尿病缺血性脑损伤中的机制研究

81771422
2017
H0914.神经保护与功能调控
叶治
面上项目
主任医师
中南大学
54万元
长链非编码RNA;线粒体自噬;Rac1;糖尿病;缺血性脑损伤
2018-01-01到2021-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Inhibition of Rac1 ameliorates neuronal oxidative stress damage via reducing Bcl-2/Rac1 complex formation in mitochondria through PI3K/Akt/mTOR pathway 期刊论文 Pan Yundan;Wang Na;Xia Pingping;Wang E.;Guo Qulian;Ye Zhi
2 长链非编码RNAMEG3在高糖诱发大鼠神经细胞损伤中的作用:与线粒体途径凋亡的关系 期刊论文 玛丽江 木拉提;王志华;陈诚;黄炎;夏萍萍;张帆;王锷;郭曲练;叶治
3 Rac1 relieves neuronal injury induced by oxygenglucose deprivation and re-oxygenation via regulation of mitochondrial biogenesis and function 期刊论文 Xia Pingping;Zhang Fan;Chen Cheng;Wang Zhihua;Wang Na;Li Longyan;Guo Qulian;Ye Zhi
4 ALDH 2 conferred neuroprotection on cerebral ischemic injury by alleviating mitochondria-related apoptosis through JNK/caspase-3 signing pathway 期刊论文 Xia Pingping;Zhang Fan;Yuan Yajing;Chen Cheng;Huang Yan;Li Longyan;Wang E.;Guo Qulian;Ye Zhi
5 Long noncoding RNA Meg3 mediates ferroptosis induced by oxygen and glucose deprivation combined with hyperglycemia in rat brain microvascular endothelial cells, through modulating the p53/GPX4 axis 期刊论文 Chen Cheng;Huang Yan;Xia Pingping;Zhang Fan;Li Longyan;Wang E;Guo Qulian;Ye Zhi
6 Rac1在糖尿病大鼠脑缺血再灌注损伤中的作用:与线粒体自噬的关系 期刊论文 陈诚;刘宇;黄炎;夏萍萍;张帆;李龙艳;叶治
7 Pioglitazone Confers Neuroprotection Against Ischemia-Induced Pyroptosis due to its Inhibitory Effects on HMGB-1/RAGE and Rac1/ROS Pathway by Activating PPAR-gamma 期刊论文 Xia Pingping;Pan Yundan;Zhang Fan;Wang Na;Wang E.;Guo Qulian;Ye Zhi
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