组织蛋白酶Cathepsin L/V促进血管内膜新生的机制研究

81730013
2017
H0202.心肌损伤、修复、重构和再生
陈丰原
重点项目
教授
中南大学
294万元
血管再狭窄;Toll样受体4;哺乳动物雷帕霉素靶蛋白复合体1;血管内膜新生;组织蛋白酶L/V
2018-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 PhospholipaseCγ1/calcium-dependent membranous localization of Gsdmd-N drives endothelial pyroptosis, contributing to lipopolysaccharide-induced fatal outcome 期刊论文 Hong Liu;Da Tang;Xiaoyu Zhou;Xiaoping Yang;Alex F Chen
2 Caspase-4/11-Mediated Pulmonary Artery Endothelial Cell Pyroptosis Contributes to Pulmonary Arterial Hypertension. 期刊论文 Yusi Wu;Bingjie Pan;Zhen Zhang;Xiaohui Li;Yiping Leng;Yong Ji;Kun Sun;Alex F Chen
3 Low-dose nifedipine rescues impaired endothelial progenitor cell-mediated angiogenesis in diabetic mice 期刊论文 Cheng Peng;Li-jun Yang;Chuan Zhang;Yu Jiang;Liu-wen-xin Shang;Jia-bei He;Zhen-wei Zhou;Xia Tao;Lu Tie;Alex F Chen;He-hui Xie
4 NRP1 regulates HMGB1 in vascular endothelial cells under high homocysteine condition 期刊论文 Yeshuo Ma;Zhen Zhang;Runtai Chen;Rui Shi;Pingyu Zeng;Ruifang Chen;Yiping Leng;Alex F Chen
5 R-spondin 3 Inhibits High Glucose-Induced Endothelial Activation Through Leucine-Rich G Protein-Coupled Receptor 4/Wnt/β-catenin Pathway. 期刊论文 Chong Chen;Hang Qu;Fang Liu;Yu Yu;Kun Sun;Alex F Chen
6 Atorvastatin Induces Mitochondria-Dependent Ferroptosis via the Modulation of Nrf2-xCT/GPx4 Axis. 期刊论文 Qi Zhang;Hang Qu;Yinghui Chen;Xueyang Luo;Chong Chen;Bing Xiao;Xiaowei Ding;Pengjun Zhao;Yanan Lu;Alex F Chen;Yu Yu
7 Protective effects of metformin in various cardiovascular diseases: Clinical evidence and AMPK-dependent mechanisms 期刊论文 Yizhi Bu;Mei Peng;Xinyi Tang;Xu Xu;Yifeng Wu;Alex F Chen;Xiaoping Yang
8 Gene Regulatory Effect of Pyruvate Kinase M2 is Involved in Renal Inflammation in Type 2 Diabetic Nephropathy 期刊论文 Le Li;Lei Tang;Xiaoping Yang;Ruifang Chen;Zhen Zhang;Yiping Leng;Alex F Chen
9 HMGB1 mediates homocysteine-induced endothelial cells pyroptosis via cathepsin V-dependent pathway 期刊论文 Yiping Leng;Ruifang Chen;Runtai Chen;Si He;Xiaoli Shi;Xiaoyu Zhou;Zhen Zhang;Alex F Chen
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