MAM脂质代谢关键蛋白在2型DN异位脂肪沉积及脂质肾损伤中的作用与机制研究
81730018
2017
H05.泌尿系统
孙林
重点项目
教授
中南大学
250万元
脂质代谢;线粒体相关内质网膜;糖尿病肾病;异位脂肪沉积;脂质肾损伤
2018-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Brenner & Rector肾脏病学(原书第11版) | 专著 | 孙林;刘友华;杨俊伟;杨天新;陈旻;蔡广研;刘必成;郑丰;丁国华;陶立坚;付平 |
| 2 | ER-Phagy: A New Regulator of ER Homeostasis | 期刊论文 | Yang Ming;Luo Shilu;Wang Xi;Li Chenrui;Yang Jinfei;Zhu Xuejing;Xiao Li;Sun Lin |
| 3 | PRDM16 Regulating Adipocyte Transformation and Thermogenesis: A Promising Therapeutic Target for Obesity and Diabetes | 期刊论文 | Jiang Na;Yang Ming;Han Yachun;Zhao Hao;Sun Lin |
| 4 | β-Hydroxybutyrate against Cisplatin-Induced acute kidney injury via inhibiting NLRP3 inflammasome and oxidative stress. | 期刊论文 | Luo Shilu;Yang Ming;Han Yachun;Zhao Hao;Jiang Na;Li Li;Chen Wei;Li Chenrui;Yang Jinfei;Liu Yan;Liu Chongbin;Zhao Chanyue;Sun Lin |
| 5 | 临床肾脏病学 | 专著 | 刘伏友;孙林;刘虹;李军;肖力;郝传明;陶立坚;蔡广研 |
| 6 | Crescents, an Independent Risk Factor for the Progression of Type 2 Diabetic Kidney Disease | 期刊论文 | Sun Liya;Duan Tongyue;Zhao Qing;Xu Lujun;Han Yachun;Xi Yiyun;Zhu Xuejing;He Liyu;Tang Chengyuan;Fu Xiao;Sun Lin |
| 7 | Disulfide-bond A oxidoreductase-like protein protects against ectopic fat deposition and lipid-related kidney damage in diabetic nephropathy | 期刊论文 | Chen Xianghui;Han Yachun;Gao Peng;Yang Ming;Xiao Li;Xiong Xiaofen;Zhao Hao;Tang Chengyuan;Chen Guochun;Zhu Xuejing;Yuan Shuguang;Liu Fuyou;Lily Q Dong;Liu Feng;Yashpal S Kanwar;Sun Lin |
| 8 | HIF-1 alpha ameliorates tubular injury in diabetic nephropathy via HO-1-mediated control of mitochondrial dynamics | 期刊论文 | Jiang Na;Zhao Hao;Han Yachun;Li Li;Xiong Shan;Zeng Lingfeng;Xiao Ying;Wei Ling;Xiong Xiaofen;Gao Peng;Yang Ming;Liu Yu;Sun Lin |
| 9 | Sex Differences in Kidney Stone Disease in Chinese Patients with Type 2 Diabetes Mellitus | 期刊论文 | Xiao Ying;Wei Ling;Xiong Xiaofen;Yang Yuan;Li Li;Yang Ming;Deng Fei;Sun Lin |
| 10 | Towards Better Drug Repositioning: Targeted Immunoinflammatory Therapy for Diabetic Nephropathy | 期刊论文 | Zhang Qin;Yang Ming;Xiao Ying;Han Yachun;Yang Shikun;Sun Lin |
| 11 | Family history of diabetes is associated with diabetic foot complications in type 2 diabetes | 期刊论文 | Xiong Xiaofen;Wei Ling;Xiao Ying;Han YaChun;Yang Jinfei;Zhao Hao;Yang Ming;Sun Lin |
| 12 | PACS-2 Ameliorates Tubular Injury by Facilitating Endoplasmic Reticulum-Mitochondria Contact and Mitophagy in Diabetic Nephropathy | 期刊论文 | Li Chenrui;Li Li;Yang Ming;Yang Jinfei;Zhao Chanyue;Han Yachun;Zhao Hao;Jiang Na;Wei Ling;Xiao Ying;Liu Yan;Xiong Xiaofen;Xi Yiyun;Luo Shilu;Deng Fei;Chen Wei;Yuan Shuguang;Zhu Xuejing;Xiao Li;Sun Lin |
| 13 | Effects of family history of diabetes on pancreatic β-cell function and diabetic ketoacidosis in newly diagnosed patients with type 2 diabetes: a cross-sectional study in China | 期刊论文 | Xiong Xiaofen;Wei Ling;Xiao Ying;Han Yachun;Yang Jinfei;Zhao Hao;Yang Ming;Sun Lin |
| 14 | The Kidney Specific Protein myo-Inositol Oxygenase, a Potential Biomarker for Diabetic Nephropathy | 期刊论文 | Gao Peng;Xu Bo;Song Panai;Zhu Xuejing;Yuan Shuguang;Yashipal S Kanwar;Sun Lin |
| 15 | DsbA-L ameliorates high glucose induced tubular damage through maintaining MAM integrity | 期刊论文 | Yang Ming;Zhao Li;Gao Peng;Zhu Xuejing;Han Yachun;Chen Xianghui;Li Li;Xiao Ying;Wei Ling;Li Chenrui;Xiao Li;Yuan Shuguang;Liu Fuyou;Lily Q. Dong;Yashpal S.Kanwar;Sun Lin |
| 16 | The Susceptibility Genes in Diabetic Nephropathy | 期刊论文 | Wei Ling;Xiao Ying;Li Li;Xiong Xiaofen;Han Yachun;Zhu Xuejing;Sun Lin |
| 17 | Acyl-CoA synthase ACSL4: an essential target in ferroptosis and fatty acid metabolism | 期刊论文 | Ding Kaiyue;Liu Chongbin;Li Li;Yang Ming;Jiang Na;Luo Shilu;Sun Lin |
| 18 | Using network pharmacology to explore the mechanism of Danggui-Shaoyao-San in the treatment of diabetic kidney disease | 期刊论文 | Yang Jinfei;Li Chenrui;Liu Yan;Han Yachun;Zhao Hao;Luo Shilu;Zhao Chanyue;Jiang Na;Yang Ming;Sun Lin |
| 19 | Targeting the NLRP3 Inflammasome in Diabetic Nephropathy | 期刊论文 | Yang Ming;Wang Xi;Han Yachun;Li Chenrui;Wei Ling;Yang Jinfei;Chen Wei;Zhu Xuejing;Sun Lin |
| 20 | DsbA-L Ameliorates Renal Injury Through the AMPK/NLRP3 Inflammasome Signaling Pathway in Diabetic Nephropathy | 期刊论文 | Yang Ming;Luo Shilu;Jiang Na;Wang Xi;Han Yachun;Zhao Hao;Xiong Xiaofen;Liu Yan;Zhao Chanyue;Zhu Xuejing;Lin Sun |
| 21 | Association Between Vitamin D Status and Diabetic Complications in Patients With Type 2 Diabetes Mellitus: A Cross-Sectional Study in Hunan China | 期刊论文 | Xiao Ying;Wei Ling;Xiong Xiaofen;Yang Ming;Sun Lin |
| 22 | Reactive oxygen species promote tubular injury in diabetic nephropathy: The role of the mitochondrial ros-txnip-nlrp3 biological axis | 期刊论文 | Han Yachun;Xu Xiaoxuan;Tang Chengyuan;Gao Peng;Chen Xianghui;Xiong Xiaofen;Yang Ming;Yang Shikun;Zhu Xuejing;Yuan Shuguang;Liu Fuyou;Xiao Li;Yashpal S Kanwar;Sun Lin |
| 23 | A Glimpse of Inflammation and Anti-Inflammation Therapy in Diabetic Kidney Disease | 期刊论文 | Liu Chongbin;Yang Ming;Li Li;Luo Shilu;Yang Jinfei;Li Chenrui;Liu Huafeng;Sun Lin |
| 24 | Effects of HIF-1α on renal fibrosis in cisplatin-induced chronic kidney disease | 期刊论文 | Zhao Hao;Han Yachun;Jiang Na;Li Chenrui;Yang Ming;Xiao Ying;Wei Ling;Xiong Xiaofen;Yang Jinfei;Tang Chengyuan;Xiao Li;Liu Fuyou;Liu Yu;Sun Lin |
| 25 | MAMs Protect Against Ectopic Fat Deposition and Lipid-Related Kidney Damage in DN Patients | 期刊论文 | Yang Ming;Han Yachun;Luo Shilu;Xiong Xiaofen;Zhu Xuejing;Zhao Hao;Jiang Na;Xiao Ying;Wei Ling;Li Chenrui;Yang Jinfei;Sun Lin |
| 26 | The comparison of albumin and 6% hydroxyethyl starches (130/0.4) in cardiac surgery: a meta-analysis of randomized controlled clinical trials | 期刊论文 | Wei Ling;Li Dongping;Sun Lin |
| 27 | Aristolochic acid induces renal fibrosis by arresting proximal tubular cells in G2/M phase mediated by HIF‐1α | 期刊论文 | Zhao Hao;Jiang Na;Han Yachun;Yang Ming;Gao Peng;Xiong Xiaofen;Xiong Shan;Zeng Lingfeng;Xiao Ying;Wei Ling;Li Li;Li Chenrui;Yang Jinfei;Tang Chengyuan;Xiao Li;Liu Fuyou;Liu Yu;Sun Lin |
| 28 | PACS-2: A key regulator of mitochondria-associated membranes (MAMs) | 期刊论文 | Li Chenrui;Li Li;Yang Ming;Zeng Lingfeng;Sun Lin |
| 29 | Mitochondrial DNA-dependent inflammation in kidney diseases | 期刊论文 | Luo Shilu;Yang Ming;Zhao Hao;Han Yachun;Liu Yan;Xiong Xiaofen;Chen Wei;Li Chenrui;Sun Lin |
| 30 | AdipoRon Protects against Tubular Injury in Diabetic Nephropathy by Inhibiting Endoplasmic Reticulum Stress | 期刊论文 | Xiong Shan;Han Yachun;Gao Peng;Zhao Hao;Jiang Na;Sun Lin |
| 31 | Lipophagy deficiency exacerbates ectopic lipid accumulation and tubular cells injury in diabetic nephropathy | 期刊论文 | Han Yachun;Xiong Shan;Zhao Hao;Yang Shikun;Yang Ming;Zhu Xuejing;Jiang Na;Xiong Xiaofen;Gao Peng;Wei Ling;Xiao Ying;Sun Lin |
| 32 | Mitochondria-Associated Membranes (MAMs): A Novel Therapeutic Target for Treating Metabolic Syndrome | 期刊论文 | Yang Ming;Li Chenrui;Sun Lin |
| 33 | Mitochondria-Associated Endoplasmic Reticulum Membranes (MAMs) and Their Prospective Roles in Kidney Disease | 期刊论文 | Gao Peng;Yang Wenxia;Sun Lin |
| 34 | The Relationship Between Simple Renal Cysts and Renal Function in Patients With Type 2 Diabetes | 期刊论文 | Wei Ling;Xiao Ying;Xiong Xiaofen;Li Li;Yang Yuan;Han Yachun;Zhao Hao;Yang Ming;Sun Lin |
| 35 | Identification of two novel subgroups in patients with diabetes mellitus and their association with clinical outcomes: A two-step cluster analysis | 期刊论文 | Xiong Xiao-fen;Yang Yuan;Wei Ling;Xiao Ying;Li Li;Sun Lin |
| 36 | Mitochondria-Associated ER Membranes – The Origin Site of Autophagy | 期刊论文 | Yang Ming;Li Chenrui;Yang Shikun;Xiao Ying;Xiong Xiaofen;Chen Wei;Zhao Hao;Zhang Qin;Han Yachun;Sun Lin |
| 37 | Association of Bowman’s capsule rupture with prognosis in patients with lupus nephritis | 期刊论文 | Duan Tongyue;Zhu Xuejing;Zhao Qing;Xiao Li;He Liyu;Liu Hong;Chen Anqun;Duan Shaobin;Yuan Shuguang;Tang Chengyuan;Yuan Fang;Zhu Jianling;Zhu Xiaoping;Cheng Meichu;Liu Yinghong;Liu Yu;Liu Fuyou;Sun Lin |
| 38 | Mitophagy: A Novel Therapeutic Target for Treating DN | 期刊论文 | Yang Ming;Li Chenrui;Yang Shikun;Xiao Ying;Chen Wei;Gao Peng;Jiang Na;Xiong Shan;Wei Ling;Zhang Qin;Yang Jinfei;Zeng Lingfeng;Sun Lin |
| 39 | Perturbations in mitochondrial dynamics by p66Shc lead to renal tubular oxidative injury in human diabetic nephropathy | 期刊论文 | Zhan Ming;Usman Irtaza;Yu Jingbo;Ruan Liemin;Bian Xueyan;Yang Jun;Yang Shikun;Sun Lin;Kanwar Yashpal S. |
| 40 | PACS-2 deficiency in tubular cells aggravates lipid-related kidney injury in diabetic kidney disease | 期刊论文 | Zhao Chanyue;Li Li;Li Chenrui;Tang Chengyuan;Cai Juan;Liu Yu;Yang Jinfei;Xi Yiyun;Yang Ming;Jiang Na;Han Yachun;Liu Yan;Luo Shilu;Xiao Li;Sun Lin |
| 41 | DsbA-L deficiency exacerbates mitochondrial dysfunction of tubular cells in diabetic kidney disease | 期刊论文 | Gao Peng;Yang Ming;Chen Xianghui;Xiong Shan;Liu Jiahao;Sun Lin |
| 42 | Caveolin-1 Regulates Cellular Metabolism: A Potential Therapeutic Target in Kidney Disease | 期刊论文 | Luo Shilu;Yang Ming;Zhao Hao;Han Yachun;Jiang Na;Yang Jinfei;Chen Wei;Li Chenrui;Liu Yan;Zhao Chanyue;Sun Lin |
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