Notch信号通过乳酸转运体调控TAMs极化和功能及在肿瘤进展中的作用机制研究
81802841
2018
H1806.肿瘤免疫
赵俊龙
青年科学基金项目
研究员
中国人民解放军第四军医大学
22万元
Notch信号;极化;乳酸转运体;肿瘤相关巨噬细胞;乳酸
2019-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Astragaloside IV Alleviates the Experimental DSS-Induced Colitis by Remodeling Macrophage Polarization Through STAT Signaling. | 期刊论文 | Tian Lianlian;Zhao Jun-Long;Kang Jian-Qin;Guo Shi-Bo;Zhang Nini;Shang Lei;Zhang Ya-Long;Zhang Jian;Jiang Xun;Lin Yan |
| 2 | Targeted delivery of miR-99b reprograms tumor-associated macrophage phenotype leading to tumor regression. | 期刊论文 | Liang Wang;Yiyang Hu;Junlong Zhao;Fei Huang;Shiqian Liang;Lei Dong;Yan Chen;Hengchao Yu;Jian Bai;Jiameng Yang;Jieyi Fan;Lei Feng;San-Zhong Li;Hua Han;Hongyan Qin |
| 3 | Phytic acid-modified CeO(2) as Ca(2+) inhibitor for a security reversal of tumor drug resistance. | 期刊论文 | Tian Zhimin;Zhao Junlong;Zhao Shoujie;Li Huicheng;Guo Zhixiong;Liang Zechen;Li Jiayuan;Qu Yongquan;Chen Dongfeng;Liu Lei |
| 4 | MicroRNA-144 represses gliomas progression and elevates susceptibility to Temozolomide by targeting CAV2 and FGF7. | 期刊论文 | Liu Zhi-Qin;Ren Jing-Jing;Zhao Jun-Long;Zang Jian;Long Qian-Fa;Du Jing-Jing;Jia Xiao-Tao;Gu Nai-Bing;Di Zheng-Li;Qian Yi-Hua;Li San-Zhong |
| 5 | Notch-mediated lactate metabolism regulates 1 MDSC development through the 2 Hes1/MCT2/c-Jun axis | 期刊论文 | Jun-long Zhao;Yu-Chen Ye;Chun-Chen Gao;Liang Wang;Kai-Xi Ren;Ru Jiang;Si-Jun Hu;Shi-Qian Liang;Jian Bai;Jia-Long Liang;Peng-Fei Ma;Yi-Yang Hu;Ben-Chang Li;Yong-Zhan Nie;Yan Chen;Xiao-Fei Li;Wei Zhang;Hua Han;Hong-Yan Qin |
| 6 | miR-139/PDE2A-Notch1 feedback circuit represses stemness of gliomas by inhibiting Wnt/β-catenin signaling. | 期刊论文 | Li San-Zhong;Ren Kai-Xi;Zhao Jing;Wu Shuang;Li Juan;Zang Jian;Fei Zhou;Zhao Jun-Long |
| 7 | Epigenetic silencing of miR-144/451a cluster contributes to HCC progression via paracrine HGF/MIF-mediated TAM remodeling. | 期刊论文 | Junlong Zhao;Huichen Li;Shoujie Zhao;Enxin Wang;Jun Zhu;Dayun Feng;Yejing Zhu;Weijia Dou;Qingling Fan;Jie Hu;Lintao Jia;Lei Liu |
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