GDF11通过调控SIRT1-SMAD2/3信号通路介导糖尿病心肌病心肌纤维化的机制研究
81770373
2017
H0207.心肌炎和心肌病
俞世强
面上项目
教授
中国人民解放军第四军医大学
55万元
心肌纤维化;沉默信息调控因子1;生长分化因子11;糖尿病心肌病;SMAD2/3
2018-01-01到2021-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Clinical profiles and outcomes of acute type A aortic dissection and intramural hematoma in the current era: lessons from the first registry of aortic dissection in China | 期刊论文 | Duan Weixun;Wang Weiguang;Xia Lin;Xue Chao;Yu Bo;Ren Kai;Yi Wei;Liang Hongliang;Dong Xiaochao;Zuo Jian;Liu Jincheng;Yu Shiqiang;Yi Dinghua |
| 2 | Melatonin protects against thoracic aortic aneurysm and dissection through SIRT1-dependent regulation of oxidative stress and vascular smooth muscle cell loss | 期刊论文 | Xia Lin;Sun Chang;Zhu Hanzhao;Zhai Mengen;Zhang Liyun;Jiang Liqing;Hou Peng;Li Junfeng;Li Kaifeng;Liu Zhenhua;Li Buying;Wang Xiaowu;Yi Wei;Liang Hongliang;Jin Zhenxiao;Yang Jian;Yi Dinghua;Liu Jincheng;Yu Shiqiang;Duan Weixun |
| 3 | 马凡综合征患者妊娠并发主动脉夹层的诊断和治疗策略 | 期刊论文 | 俞波;张婷;刘振华;陈涛 |
| 4 | Total arch repair with open placement of a novel double-branched stent graft for acute Type A aortic dissection: a single-centre experience with 21 consecutive patients. | 期刊论文 | Yu Bo;Liu Zhenhua;Xue Chao;Liu Jincheng;Yang Jian;Jin Zhenxiao;Yu Shiqiang;Duan Weixun |
| 5 | 糖尿病心脏中血管损伤病理特征的研究 | 期刊论文 | 李凯峰;翟蒙恩;宋凡;江丽青;李捷;何萌杉;梁宏亮;金振晓;段维勋;王四旺 |
| 6 | 褪黑素减轻心肌缺血再灌注损伤的新机制 | 期刊论文 | 张彬;翟蒙恩;李凯峰;李步潆;刘振华;陈正希;江丽青;梁宏亮;段维勋;金振晓;俞世强 |
| 7 | 基于基因诊断的主动脉外科治疗现状与展望 | 期刊论文 | 薛超;段维勋;易定华;俞世强 |
| 8 | Standford B型主动脉夹层腔内修复术后逆行A型夹层手术治疗的临床疗效 | 期刊论文 | 俞波;刘振华;刘振华;金振晓;刘金成;俞世强 |
| 9 | 中药皂苷成分对高血压大鼠主动脉血管内皮功能相关因子的影响 | 期刊论文 | 任恺;段维勋;俞波;刘洋;李步潆;金振晓;俞世强 |
| 10 | 覆膜支架腔内修复术对Stanford B型主动脉夹层动脉瘤患者术后血清血管内皮生长因子、核因子-κB水平的影响 | 期刊论文 | 任恺;李步潆;段维勋;俞波;俞世强;金振晓 |
| 11 | GDF11 Alleviates Pathological Myocardial Remodeling in Diabetic Cardiomyopathy Through SIRT1-Dependent Regulation of Oxidative Stress and Apoptosis | 期刊论文 | Zhu Hanzhao;Zhang Liyun;Zhai Mengen;Xia Lin;Cao Yu;Xu Lu;Li Kaifeng;Jiang Liqing;Shi Heng;Li Xiang;Zhou Yenong;Ding Wei;Wang Dongxu;Gao Erhe;Liu Jincheng;Yu Shiqiang;Duan Weixun |
| 12 | GPR 30 reduces myocardial infarct area and fibrosis in female ovariectomized mice by activating the PI3K/AKT pathway | 期刊论文 | Wang Xiaowu;Lu Linhe;Tan Yanzhen;Jiang Liqing;Zhao Minggao;Gao Erhe;Yu Shiqiang;Liu Jincheng |
| 13 | 四氢姜黄素对2 型糖尿病小鼠糖脂代谢及大血管病变的影响 | 期刊论文 | 江丽青;李凯峰;翟蒙恩;夏 麟;王晓武;俞世强;段维勋 |
| 14 | Honokiol Ameliorates Myocardial Ischemia/Reperfusion Injury in Type 1 Diabetic Rats by Reducing Oxidative Stress and Apoptosis through Activating the SIRT1-Nrf2 Signaling Pathway | 期刊论文 | Zhang Bin;Zhai Mengen;Li Buying;Liu Zhenhua;Li Kaifeng;Jiang Liqing;Zhang Meng;Yi Wei;Yang Jian;Yi Dinghua;Liang Hongliang;Jin Zhenxiao;Duan Weixun;Yu Shiqiang |
| 15 | 和厚朴酚对小鼠脓毒症心肌损伤的保护作用 | 期刊论文 | 翟蒙恩;张彬;李凯峰;夏麟;李俊峰;李步潆;刘振华;梁宏亮;金振晓;段维勋;俞世强 |
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