交感信号激活软骨细胞线粒体自噬促进TMJ-OA软骨退变的机制研究
81870787
2018
H1506.味觉、口颌面疼痛、咬合及颞下颌关节疾病
焦凯
面上项目
研究员
中国人民解放军第四军医大学
57万元
软骨细胞;交感神经信号;骨关节炎;线粒体自噬;颞下颌关节
2019-01-01到2022-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | 神经-骨偶联机制促异位骨化进展的研究进展 | 期刊论文 | 张滋彬;万千千;覃文聘;卢伟诚;韩潇潇;焦凯 |
| 2 | 陕西省自然科学优秀学术论文二等奖 | 奖励 | 牛丽娜;焦凯;李莫;王立国等 |
| 3 | 一种唾液腺起搏器 | 专利 | 焦凯;牛丽娜;闫舰飞;卢伟诚 |
| 4 | Multifunctional nanomachinery for enhancement of bone healing | 期刊论文 | Shen MJ;Wang CY;Hao DX;Hao JX;Zhu YF;Han XX ;Tonggu L;Chen JH;Jiao K;Tay FR;Niu LN |
| 5 | Biological and synthetic template-directed syntheses of mineralized hybrid and inorganic materials | 期刊论文 | Chenyu Wang;Kai Jiao;Jianfei Yan;Meichen Wan;Qianqian Wan;Lorenzo Breschi;Jihua Chen;Franklin R Tay;Lina Niu |
| 6 | Extracellular DNA: A missing link in the pathogenesis of ectopic mineralization | 期刊论文 | Shen MJ;Jiao K;Wang CY;Ehrlich H;Wan MC;Hao DX;Li J;Wan QQ;Tonggu L;Yan JF;Wang KY;Ma YX;Chen JH;Tay FR;Niu LN |
| 7 | 陕西省杰出青年科学基金 | 奖励 | 焦凯 |
| 8 | Silicified collagen scaffold induces semaphorin 3A secretion by sensory nerves to improve in-situ bone regeneration. | 期刊论文 | Ma YX;Jiao K;Wan QQ;Li J;Liu MY;Zhang ZB;Qin W;Wang KY;Wang YZ;Tay FR;Niu LN |
| 9 | 一种基于VR技术的军事飞行员口颌心理应激训练系统 | 专利 | 焦凯;牛丽娜;李博;刘青;于世宾;黄鹏 |
| 10 | MicroRNA-29b Promotes Subchondral Bone Loss in TMJ Osteoarthritis | 期刊论文 | Sun J. L.;Yan J. F.;Yu S. B.;Zhao J.;Lin Q. Q.;Jiao K. |
| 11 | Polyphosphate-crosslinked collagen scaffolds for hemostasis and alveolar bone regeneration after tooth extraction | 期刊论文 | Gu JT;Jiao K;Li J;Yan JF;Wang KY;Wang F;Liu Y;Tay FR;Chen JH;Niu LN |
| 12 | 一种自矿化胶原膜、制备方法与应用 | 专利 | 焦凯;牛丽娜;李婧 |
| 13 | Conditional deletion of Adrb2 in mesenchymal stem cells attenuates osteoarthritis-like defects in temporomandibular joint. | 期刊论文 | Sun JL;Yan JF;Li J;Wang WR;Yu SB;Zhang HY;Huang F;Niu LN;Jiao K |
| 14 | Matrix stiffening by self-mineralizable guided bone regeneration | 期刊论文 | Jing Li;Jianfei Yan;Qianqian Wan;Minjuan Shen;Yuxuan Ma;Junting Gu;Peng Gao;Xiaoyi Tang;Fan Yu;Jihua Chen;Franklin R Tay;Kai Jiao;Lina Niu |
| 15 | 陕西省科技进步一等奖 | 奖励 | 陈吉华;牛丽娜;焦凯;李岩;周唯;张少峰;马楚凡;王富;方明;宋群;沈丽娟 |
| 16 | 口腔微生态在临床应用中的研究进展 | 期刊论文 | 张雨凇;覃文聘;何佳颖;焦凯 |
| 17 | 一种基于虚拟现实的军事飞行员应激训练系统 | 专利 | 焦凯;牛丽娜;李博;黄鹏 |
| 18 | 仿生硅化较原材料的制备方法及应用 | 专利 | 焦凯;牛丽娜;马雨轩;万美辰;万千千 |
| 19 | 军队创新人才工程青年英才 | 奖励 | 焦凯 |
| 20 | Smart, Biomimetic Periosteum Created from the Cerium(III, IV) Oxide-Mineralized Eggshell Membrane | 期刊论文 | Qianqian Wan;Kai Jiao;Yuxuan Ma;Bo Gao;Zhao Mu;Yirong Wang;Yanhao Wang;Lian Duan;Kehui Xu;Junting Gu;Jianfei Yan;Jing Li;Minjuan Shen;Franklin R Tay;Lina Niu |
| 21 | Pathological calcification in osteoarthritis: an outcome or a disease initiator? | 期刊论文 | Yan JF;Qin WP;Xiao BC;Wan QQ;Tay FR;Niu LN;Jiao K |
| 22 | Crosstalk between bone and nerves within bone. | 期刊论文 | Wan QQ;Qin WP;Ma YX;Shen MJ;Li J;Zhang ZB;Chen JH;Tay FR;Niu LN;Jiao K |
| 23 | Regulation and Reconstruction of Cell Phenotype Gradients Along the Tendon-Bone Interface | 期刊论文 | Gaopeng Dang;Wen Qin;Qianqian Wan;Junting Gu;Kaiyan Wang;Zhao Mu;Bo Gao;Kai Jiao;Franklin R Tay;Lina Niu |
| 24 | A biomaterial-based therapy using a sodium hyaluronate/bioglass composite hydrogel for the treatment of oral submucous fibrosis. | 期刊论文 | Zhenxing Guo;Zhaowenbin Zhang;Jianfei Yan;Haoqing Xu;Shuyan Wang;Tao Ye;Xiaoxiao Han;Wanrong Wang;Yue Wang;Jialu Gao;Lina Niu;Jiang Chang;Kai Jiao |
| 25 | Autophagic LC3+ calcified extracellular vesicles initiate cartilage calcification in osteoarthritis. | 期刊论文 | Jianfei Yan;Minjuan Shen;Bingdong Sui;Weicheng Lu;Xiaoxiao Han;Qianqian Wan;Yingying Liu;Junjun Kang;Wenpin Qin;Zibing Zhang;Da Chen;Yuan Cao;Siqi Ying;Franklin R. Tay;Li-na Niu;Kai Jiao |
| 26 | Simultaneous regeneration of bone and nerves through materials and architectural design: Are we there yet? | 期刊论文 | Wan QQ;Qin WP;Shen MJ;Ma YX;Li B;Liu SY;Tay FR;Jiao K;Niu LN |
| 27 | 线粒体功能与口腔鳞状细胞癌关系的研究进展 | 期刊论文 | 唐笑怡;张攀;王凯燕;牛丽娜;焦凯;肖玉鸿 |
| 28 | Immunomodulatory effects of tricalcium silicate-based cements on osteogenesis. | 期刊论文 | Wan QQ;Sun JL;Ma YX;Noble LC;Dong Y;Feng ZH;Gu JT;Wang YR;Wang WR;Bergeron BE;Jiao K;Tay FR;Niu LN |
| 29 | Upregulation of mitochondrial dynamics is responsible for osteogenic differentiation of mesenchymal stem cells cultured on self-mineralized collagen membranes | 期刊论文 | Meichen Wan;Xiaoyi Tang;Jing Li;Peng Gao;Fu Wang;Minjuan Shen;Junting Gu;Franklin Tay;Jihua Chen;Lina Niu;Yuhong Xiao;Kai Jiao |
| 30 | 国家“万人计划”青年拔尖人才 | 奖励 | 焦凯 |
| 31 | 一种仿生矿化胶原-糖胺聚糖材料制备方法及应用 | 专利 | 焦凯;牛丽娜;万千千;马雨轩;万美辰;王晨语;许克惠 |
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