含FRG1基因突变体的先天性马蹄内翻足疾病iPS细胞模型的建立及发病机制的初步探讨

81472043
2014
H0601.运动系统结构、功能和发育异常
颉强
面上项目
教授
中国人民解放军第四军医大学
60万元
FRG1基因;基因突变;诱导多能干细胞;分子机理;先天性马蹄内翻足
2015-01-01到2018-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 先天性马蹄内翻足诱导多能干细胞建立及鉴定 期刊论文 胡雅茜;范静;高祎;杨柳;颉强
2 Disturbed MEK/ERK signaling increases osteoclast activity via the Hedgehog-Gli pathway in postmenopausal osteoporosis 期刊论文 Li Xiaojie;Jie Qiang;Zhang Hongyang;Zhao Yantao;Lin Yangjing;Du Junjie;Shi Jun;Wang Long;Guo Kai;Li Yong;Wang Chunhui;Gao Bo;Huang Qiang;Liu Jian;Yang Liu;Luo Zhuojing
3 骨髓间充质干细胞移植应用于骨科的研究进展 期刊论文 高祎;杨柳
4 Eicosapentaenoic acid attenuates dexamethasome-induced apoptosis by inducing adaptive autophagy via GPR120 in murine bone marrow-derived mesenchymal stem cells 期刊论文 Gao B.;Han Y-H;Wang L.;Lin Y-J;Sun Z.;Lu W-G;Hu Y-Q;Li J-Q;Lin X-S;Liu B-H;Jie Q.;Yang L.;Luo Z-J
5 Dose-response estrogen promotes osteogenic differentiation via GPR40 (FFAR1) in murine BMMSCs. 期刊论文 Gao Bo;Huang Qiang;Jie Qiang;Wang Long;Zhang Hong-Yang;Liu Jian;Yang Liu;Luo Zhuo-Jing
6 Glucocorticoids: Dose-related effects on osteoclast formation and function via reactive oxygen species and autophagy. 期刊论文 Shi Jun;Wang Long;Zhang Hongyang;Jie Qiang;Li Xiaojie;Shi Qiyue;Huang Qiang;Gao Bo;Han Yuehu;Guo Kai;Liu Jian;Yang Liu;Luo Zhuojing
7 Intramembranous ossification and endochondral ossification are impaired differently between glucocorticoid-induced osteoporosis and estrogen deficiency-induced osteoporosis 期刊论文 Zhang H;Shi J;Wang L;Li X;Zheng C;Gao B;Xu X;Lin X;Wang J;Lin Y;Shi J;Huang Q;Luo Z;Yang L
8 GPR120: A bi-potential mediator to modulate the osteogenic and adipogenic differentiation of BMMSCs. 期刊论文 Gao Bo;Huang Qiang;Jie Qiang;Lu Wei-Guang;Wang Long;Li Xiao-Jie;Sun Zhen;Hu Ya-Qian;Chen Li;Liu Bao-Hua;Liu Jian;Yang Liu;Luo Zhuo-Jing
9 Local delivery of tetramethylpyrazine eliminates the senescent phenotype of bone marrow mesenchymal stromal cells and creates an anti-inflammatory and angiogenic environment in aging mice 期刊论文 Gao B;Lin X;Jing H;Fan J;Ji C;Jie Q;Zheng C;Wang D;Xu X;Hu Y;Lu W;Luo Z;Yang L
10 Chondrocytes-osteoblast transition in endochondral ossification 期刊论文 Wang L;Jie Q;Yang L
11 Anti-osteoporotic effects of tetramethylpyrazine via promoting osteogenic differentiation and inhibiting osteoclast formation 期刊论文 Wang L;Lu W;Shi J;Zhang H;Xu X;Gao B;Huang Q;Li X;Hu Y;Jie Q;Luo Z;Yang L
12 Expression of CD147, PCNA, VEGF, MMPs and their clinical significance in the giant cell tumor of bones. 期刊论文 Han Yue-Hu;Gao Bo;Huang Jing-Hui;Wang Zhen;Guo Zheng;Jie Qiang;Yang Liu;Luo Zhuo-Jing
13 Tetramethylpyrazine protects against glucocorticoid-induced apoptosis by promoting autophagy in mesenchymal stem cells and improves bone mass in glucocorticoid-induced osteoporosis rats. 期刊论文 Wang Long;Zhang Hong-Yang;Gao Bo;Shi Jun;Huang Qiang;Han Yue-Hu;Hu Ya-Qian;Lu Wei-Guang;Zhao Zhuo-Jie;Liu Bao-Hua;Jie Qiang;Yang Liu;Luo Zhuo-Jing
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