炎性微环境下组蛋白去乙酰化酶通过调控miR-17-92家族影响牙周膜干细胞再生能力的机制研究
81470710
2014
H1502.口腔颅颌面组织器官缺损修复与再生
金岩
面上项目
教授
中国人民解放军第四军医大学
73万元
牙周再生;组蛋白去乙酰化酶;炎性微环境;牙周膜干细胞;miR-17-92
2015-01-01到2018-12-31
- 中英文摘要
- 结题摘要
- 结题报告
- 项目成果
- 项目参与人
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| 序号 | 标题 | 类型 | 作者 |
|---|---|---|---|
| 1 | Microenvironmental Views on Mesenchymal Stem Cell Differentiation in Aging | 期刊论文 | Sui B. D.;Hu C. H.;Zheng C. X.;Jin Y. |
| 2 | Composite cell sheet for periodontal regeneration: crosstalk between different types of MSCs in cell sheet facilitates complex periodontal-like tissue regeneration | 期刊论文 | Zhang Hao;Liu Shiyu;Zhu Bin;Xu Qiu;Jin Yan;Zhang Hao;Ding Yin;Zhang Hao;Liu Shiyu;Zhu Bin;Xu Qiu;Jin Yan;Zhu Bin;Xu Qiu;Jin Y;Ding Y;Jin Y |
| 3 | Allogeneic Mesenchymal Stem Cell Therapy Promotes Osteoblastogenesis and Prevents Glucocorticoid-Induced Osteoporosis | 期刊论文 | Sui Bingdong;Hu Chenghu;Zhang Xinyi;Zhao Pan;He Tao;Zhou Cuihong;Qiu Xinyu;Chen Nan;Zhao Xinyi;Jin Yan |
| 4 | Estrogen preserves Fas ligand levels by inhibiting microRNA-181a in bone marrow-derived mesenchymal stem cells to maintain bone remodeling balance | 期刊论文 | Shao Bingyi;Liao Li;Yu Yang;Shuai Yi;Jing Huan;Jin Yan;Liao Li;Shuai Yi;Jing Huan;Liao Li;Shuai Yi;Jing Huan;Jin Yan;Shao Bingyi;Yu Yang;Yang Deqin;Shao Bingyi;Yu Yang;Yang Deqin;Su Xiaoxia;Jin Y |
| 5 | MiR-26a functions oppositely in osteogenic differentiation of BMSCs and ADSCs depending on distinct activation and roles of Wnt and BMP signaling pathway | 期刊论文 | Su X.;Zhou H.;Su X.;Liao L.;Shuai Y.;Jing H.;Liu S.;Jin Y.;Su X.;Liu Y.;Liao L.;Shuai Y.;Jing H.;Liu S.;Jin Y.;Liao L.;Shuai Y.;Jing H.;Liu S.;Jin Y |
| 6 | TNF- Inhibits FoxO1 by Upregulating miR-705 to Aggravate Oxidative Damage in Bone Marrow-Derived Mesenchymal Stem Cells during Osteoporosis | 期刊论文 | Liao Li;Su Xiaoxia;Yang Xiaohong;Hu Chenghu;Li Bei;Lv Yajie;Shuai Yi;Jing Huan;Deng Zhihong;Jin Yan |
| 7 | Mechanical stress regulates osteogenic differentiation and RANKL/OPG ratio in periodontal ligament stem cells by the Wnt/beta-catenin pathway | 期刊论文 | Zhang Liqiang;Liu Wenjia;Zhao Jiangdong;Ma Xiaojie;Shen Lin;Zhang Yongjie;Jin Fang;Jin Yan |
| 8 | GCN5 modulates osteogenic differentiation of periodontal ligament stem cells through DKK1 acetylation in inflammatory microenvironment | 期刊论文 | Li Bei;Sun Jin;Dong Zhiwei;Xue Peng;He Xiaoning;Liao Li;Yuan Lin;Jin Yan |
| 9 | Knockdown of MicroRNA Let-7a Improves the Functionality of Bone Marrow-Derived Mesenchymal Stem Cells in Immunotherapy | 期刊论文 | Yu Yang;Liao Li;Shao Bingyi;Shuai Yi;Wang Han;Shang Fengqing;Zhou Zhifei;Jin Yan;Yu Yang;Shao Bingyi;Yang Deqin;Yu Yang;Shao Bingyi;Yang Deqin;Liao Li;Shuai Yi;Shang Fengqing;Jin Yan;Liao Li;Shuai Yi;Shang Fengqing;Su Xiaoxia;Wang Han;Zhou Zhifei;Yu Yang;Shao Bingyi;Yang Deqin;Yang DQ;Jin Y |
| 10 | Jawbone microenvironment promotes periodontium regeneration by regulating the function of periodontal ligament stem cells. | 期刊论文 | Zhu Bin;Liu Wenjia;Liu Yihan;Zhao Xicong;Zhang Hao;Luo Zhuojing;Jin Yan |
| 11 | microRNA-21 Contributes to Orthodontic Tooth Movement | 期刊论文 | Chen N.;Sui B. D.;Hu C. H.;Cao J.;Zheng C. X.;Hou R.;Yang Z. K.;Zhao P.;Chen Q.;Yang Q. J.;Jin Y.;Jin F. |
| 12 | Heparin improves BMSC cell therapy: Anticoagulant treatment by heparin improves the safety and therapeutic effect of bone marrow-derived mesenchymal stem cell cytotherapy | 期刊论文 | Liao Li;Shi Bingzheng;Chang Heran;Zhang Lichao;Bi Chunsheng;Shuai Yi;Jin Yan;Liao Li;Shi Bingzheng;Chang Heran;Zhang Lichao;Bi Chunsheng;Shuai Yi;Jin Yan;Liao Li;Shi Bingzheng;Chang Heran;Zhang Lichao;Bi Chunsheng;Shuai Yi;Jin Yan;Liao Li;Shuai Yi;Jin Yan;Shi Bingzheng;Chang Heran;Zhang Lichao;Su Xiaoxia;Du Xiaoyan;Deng Zhihong;Jin Y;Deng ZH |
| 13 | Mesenchymal progenitors in osteopenias of diverse pathologies: differential characteristics in the common shift from osteoblastogenesis to adipogenesis | 期刊论文 | Sui Bingdong;Hu Chenghu;Liao Li;Chen Yichen;Zhang Xinyi;Fu Xin;Zheng Chenxi;Li Meng;Wu Ling;Zhao Xinyi;Jin Yan |
| 14 | Influence of nanotopography on periodontal ligament stem cell functions and cell sheet based periodontal regeneration | 期刊论文 | Gao Hui;Li Bei;Zhao Lingzhou;Jin Yan |
| 15 | Licochalcone A up-regulates of FasL in mesenchymal stem cells to strengthen bone formation and increase bone mass. | 期刊论文 | Ming Leiguo;Jin Fang;Huang Ping;Luo Hailang;Liu Wenjia;Zhang Leilei;Yuan Wei;Zhang Yongjie;Jin Yan |
| 16 | Increased autophagy is required to protect periodontal ligament stem cells from apoptosis in inflammatory microenvironment | 期刊论文 | An Ying;Liu Wenjia;Xue Peng;Zhang Yongjie;Wang Qintao;Jin Yan |
| 17 | Melatonin Treatment Improves Mesenchymal Stem Cells Therapy by Preserving Stemness during Long-term In Vitro Expansion | 期刊论文 | Shuai Yi;Liao Li;Yu Yang;Shao Bingyi;Jing Huan;Zhang Xinjing;Jin Yan;Shuai Yi;Liao Li;Jing Huan;Jin Yan;Su Xiaoxia;Yu Yang;Shao Bingyi;Zhang Xinjing;Deng Zhihong;Jin Y;Jin Y;Deng ZH |
| 18 | Declining histone acetyltransferase GCN5 represses BMSC-mediated angiogenesis during osteoporosis | 期刊论文 | Jing Huan;Liao Li;Shuai Yi;Jin Yan;Jing Huan;Liao Li;Shuai Yi;Jin Yan;Jing Huan;Liao Li;Shuai Yi;Jin Yan;Deng Zhihong;Jing Huan;Liao Li;Shuai Yi;Jin Yan;Su Xiaoxia;Zhang Xinjing;Jin Y;Deng ZH |
| 19 | Decreased MORF leads to prolonged endoplasmic reticulum stress in periodontitis-associated chronic inflammation | 期刊论文 | Xue Peng;Li Bei;An Ying;Sun Jin;He Xiaoning;Hou Rui;Dong Guangying;Fei Dongdong;Jin Fang;Wang Qintao;Jin Yan |
| 20 | Suppression of EZH2 Prevents the Shift of Osteoporotic MSC Fate to Adipocyte and Enhances Bone Formation During Osteoporosis | 期刊论文 | Jing Huan;Liao Li;An Yulin;Liu Shiyu;Shuai Yi;Jin Yan;Jing Huan;Liao Li;An Yulin;Liu Shiyu;Shuai Yi;Jin Yan;Jing Huan;Liao Li;An Yulin;Liu Shiyu;Shuai Yi;An Yulin;Su Xiaoxia;Zhang Xinjing;Jin Y |
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