基于SERS在线检测技术的CPC发酵生产过程监测及反馈控制优化研究

21878339
2018
B0805.过程强化与化工装备
陈晓青
面上项目
教授
中南大学
66万元
发酵过程在线监测;头孢菌素C;表面增强拉曼光谱;反馈控制优化;实时检测
2019-01-01到2022-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Isotope-coding derivatization for quantitative profiling of reactive α-dicarbonyl species in processed botanicals by liquid chromatography-tandem mass spectrometry 期刊论文 Meiling Wang;Yaxuan Liu;Bin Guo;Fan Zhang;Fang Chou;Ming Ma;Libin Huang;Ziwei Luo;Bo Chen;Xiaoqing Chen
2 Polyethyleneimine functionalized multi-walled carbon nanotubes-based solid phase extraction for selective screening of carboxylic acid compounds in natural products 期刊论文 Xueqian Huang;Minzhuo Liu;Xiong Liu;Qi Liu;Xiaoqing Chen
3 Framework nucleic acid programmed combinatorial delivery nanocarriers for parallel and multiplexed analysis 期刊论文 Yinghui Feng;Qi Liu;Miao Chen;Xinyi Zhao;Lumin Wang;Longfei Liu;Xiaoqing Chen
4 Large-scale separation of acetylcholinesterase inhibitors from Zanthoxylum nitidum by pH-zone-refining counter-current chromatography target-guided by ultrafiltration high-performance liquid chromatography with ultraviolet and mass spectrometry screening 期刊论文 Liu Minzhuo;Liu Qi;Chen Miao;Huang Xueqian;Chen Xiaoqing
5 Cation polymer-induced aggregation of water-soluble Au(I)-thiolate complexes and its photoluminescent properties 期刊论文 Naiying Hao;Yitao Cao;Ruili Li;Hongbin Lin;Huiting Shan;Tiankai Chen;Osburg Jin Huang Chai;Qiaofeng Yao;Xiaoqing Chen;Jianping Xie
6 湖南省自然科学奖 奖励 陈晓青
7 Facile construction of a reusable multi-enzyme cascade bioreactor for effective fluorescence discrimination and quantitation of amino acid enantiomers 期刊论文 Guangjuan Liu;Lumin Wang;Fawei Zhu;Qi Liu;Yinghui Feng;Xinyi Zhao;Miao Chen;Xiaoqing Chen
8 AIE-active metal-organic frameworks: facile preparation, tunable light emission, ultrasensitive sensing of copper(ii) and visual fluorescence detection of glucose 期刊论文 Xie Siqi;Liu Qi;Zhu Fawei;Chen Miao;Wang Lumin;Xiong Yu;Zhu Yuqiu;Zheng Yu;Chen Xiaoqing
9 A dual-channel probe based on copper ion-mediated metal organic framework composite for colorimetric and ratiometric fluorescence monitoring ofglyphosate degradation in soil and water. 期刊论文 Yuni Yuan;Wei liu;Qi Liu;Qing He;Yuyang Hu;Xinyu Jiang;Xiaoqing Chen
10 Development of a "dual gates" locked, target-triggered nanodevice for point-of-care testing with a glucometer readout 期刊论文 Wang Lumin;Zhu Fawei;Chen Miao;Xiong Yu;Zhu Yuqiu;Xie Siqi;Liu Qi;Yang Hua;Chen Xiaoqing
11 Framework nucleic acid-based spatial-confinement amplifier for miRNA imaging in living cells 期刊论文 Yinghui Feng;Qi Liu;Xinyi Zhao;Miao Chen;Xiaotong Sun;Hongxia Li;Xiaoqing Chen
12 L-pyroglutamic acid-modified CdSe/ZnS quantum dots: A new fluorescence-responsive chiral sensing platform for stereospecific molecular recognition 期刊论文 Zhu Fawei;Wang Jing;Xie Siqi;Zhu Yuqiu;Wang Lumin;Xu Jinju;Liao Sen;Ren Jiwei;Liu Qi;Yang Hua;Chen Xiaoqing
13 Intelligent platform for simultaneous detection of multiple aminoglycosides based on ratiometric paper-based device with digital fluorescence detector readout 期刊论文 Lumin Wang;Fawei Zhu;Yuqiu Zhu;Siqi Xie;Miao Chen;Yu Xiong;Qi Liu;Hua Yang;Xiaoqing Chen
14 Self-propelled quantum dots-based spherical nucleic amplifier for ratiometric imaging of intracellular microRNAs 期刊论文 Xinyi Zhao;Hai Wang;Yinghui Feng;Hexiang Li;Qi Liu;Xiaoqing Chen
15 Deep learning-based multicapturer SERS platform on plasmonic nanocube metasurfaces for multiplex detection of organophosphorus pesticides in environmental water 期刊论文 Ruili Li;Zi Wang;Zhipeng Zhang;Xiaotong Sun;Yuyang Hu;Haoyang Wang;Kecen Chen;Qi Liu;Miao Chen;Xiaoqing Chen
16 Hydrogel-integrated microfluidic platform for separation-free colorimetric and distance-based detection of biomarkers in whole blood 期刊论文 Wei Liu;Yuni Yuan;Qi Liu;Miao Chen;Xiaoqing Chen
17 Separation of alpha-glucosidase inhibitors from Potentilla kleiniana Wight et Arn using solvent and flow-rate gradient high-speed counter-current chromatography target-guided by ultrafiltration HPLC-MS screening 期刊论文 Liu Minzhuo;Huang Xueqian;Liu Qi;Li Xujie;Chen Miao;Zhu Yuqiu;Chen Xiaoqing
18 Facile synthesis of B,N-doped CQDs as versatile fluorescence probes for sensitive detection of cobalt ions in environmental water and biological samples 期刊论文 Zhao Xinyi;Wang Lumin;Liu Qi;Chen Miao;Chen Xiaoqing
19 Cu2+ assisted carnation-like fluorescent metal–organic framework for triple-mode detection of glyphosate in food samples 期刊论文 Jianping Guan;Qing He;Qi Liu;Xiaoqing Chen
20 Comprehensive profiling of alpha-glucosidase inhibitors from the leaves of Rubus suavissimus using an off-line hyphenation of HSCCC, ultrafiltration HPLC-UV-MS and prep-HPLC 期刊论文 Liu Minzhuo;Li Xujie;Liu Qi;Xie Siqi;Chen Miao;Wang Lumin;Feng Yinghui;Chen Xiaoqing
21 Single-stranded DNA modified protonated graphitic carbon nitride nanosheets: A versatile ratiometric fluorescence platform for multiplex detection of various targets 期刊论文 Wang Lumin;Zhu Fawei;Liao Sen;Chen Miao;Zhu Yu Qiu;Liu Qi;Chen Xiaoqing
22 "Pomegranate-like" plasmonic nanoreactors with accessible high-density hotspots for in situ SERS monitoring of catalytic reactions 期刊论文 Hao Naiying;Chen Miao;Yang Hua;Li Ruili;Liu Qi;Zhu Yuqiu;Wang Lumin;Peng Mei;Xiang Juan;Chen Xiaoqing
23 Preparative isolation and purification of twelve main antioxidants from the roots of Polygonum multiflo rum Thunb using high‐speed counter‐current chromatography and preparative HPLC guided by 1, 1’‐diphenyl‐2‐picrylhydrazyl‐HPLC 期刊论文 Minzhuo Liu;Xujie Li;Qi Liu;Siqi Xie;Fawei Zhu;Xiaoqing Chen
24 Synthesis of camphor sulfonic acid derivatives modified Mg/Al-LDH for efficient separation of propranolol enantiomers 期刊论文 Tianqi Yuan;Miao Chen;Xiaotong Sun;Jianping Guan;Fawei Zhu;Kai Tang;Zhipeng Zhang;Qi Liu;Xiaoqing Chen
25 Simultaneous in situ extraction and self-assembly of plasmonic colloidal gold superparticles for SERS detection of organochlorine pesticides in water 期刊论文 Li Ruili;Chen Miao;Yang Hua;Hao Naiying;Liu Qi;Peng Mei;Wang Lumin;Hu Yuyang;Chen Xiaoqing
26 In situ growth of ZIF-8 on gold nanoparticles/magnetic carbon nanotubes for the electrochemical detection of bisphenol A 期刊论文 Li Hexiang;Zhu Fawei;Xiang Jun;Wang Fangbin;Liu Qi;Chen Xiaoqing
27 Facile green and one-pot synthesis of purple perilla derived carbon quantum dot as a fluorescent sensor for silver ion 期刊论文 Zhao Xinyi;Liao Sen;Wang Lumin;Liu Qi;Chen Xiaoqing
28 Single-atom Rh nanozyme: An efficient catalyst for highly sensitive colorimetric detection of acetylcholinesterase activity and adrenaline 期刊论文 Jianping Guan;Meng Wang;Runze Ma;Qi Liu;Xiaotong Sun;Yu Xiong;Xiaoqing Chen
29 AIEgen modulated per-functionalized flower-like IRMOF-3 frameworks with tunable light emission and excellent sensing properties 期刊论文 Li Xujie;Xie Siqi;Hu Yuanzhuo;Xiang Jun;Wang Lumin;Li Ruili;Chen Miao;Wang Fangbin;Liu Qi;Chen Xiaoqing
30 Differential pulse voltammetry determination of ofloxacin in human serum and urine based on a novel tryptophan-graphene oxide-carbon nanotube electrochemical sensor 期刊论文 Zhu Yuqiu;Li Chengkun;Wang Lumin;Chen Miao;Yu Jingang;Liu Qi;Chen Xiaoqing
31 Integrating target-triggered aptamer-capped HRP@metal-organic frameworks with a colorimeter readout for on-site sensitive detection of antibiotics 期刊论文 Wang Lumin;Liu Guangjuan;Ren Yuxiang;Feng Yinghui;Zhao Xinyi;Zhu Yuqiu;Chen Miao;Zhu Fawei;Liu Qi;Chen Xiaoqing
32 High quantum-yield carbon dots embedded metal-organic frameworks for selective and sensitive detection of dopamine 期刊论文 Xie Siqi;Li Xujie;Wang Lumin;Zhu Fawei;Zhao Xinyi;Yuan Tianqi;Liu Qi;Chen Xiaoqing
33 Integrating amino acid oxidase with photoresponsive probe: A fast quantitative readout platform of amino acid enantiomers 期刊论文 Zhu F.;Yuan T.;Jing W.;Chen K.;Wang L.;Fu Q.;Guan J.;Chen M.;Liu Q.;Yang H.;Chen X.
34 Deep learning-based label-free surface-enhanced Raman scattering screening and recognition of small-molecule binding sites in proteins 期刊论文 Mei Peng;Zi Wang;Xiaotong Sun;Xiangwei Guo;Haoyang Wang;Ruili Li;Qi Liu;Miao Chen;Xiang Chen
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