衰老微环境中HDAC9调控自噬影响骨髓间充质干细胞再生能力的机制研究

31571532
2015
C1205.组织器官稳态维持与再生修复
刘文佳
面上项目
教授
中国人民解放军第四军医大学
60万元
微环境;干细胞再生;小鼠;组蛋白修饰;衰老
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Alpl prevents bone ageing sensitivity by specifically regulating senescence and differentiation in mesenchymal stem cells. 期刊论文 liu wenjia;zhang liqiang;xuan kun;hu chenghu;liu shiyu;liao li;li bei;jin fang;shi songtao;jin yan
2 Increase in HDAC9 suppresses myoblast differentiation via epigenetic regulation of autophagy in hypoxia. 期刊论文 zhang z;zhang liqiang;zhou you;zhao jiangdong;qin wen;jin zuolin;liu wenjia
3 Autophagy Maintains the Function of Bone Marrow Mesenchymal Stem Cells to Prevent Estrogen Deficiency-Induced Osteoporosis 期刊论文 Qi Meng;Zhang Liqiang;Ma Yang;Shuai Yi;Li Liya;Luo Kefu;Liu Wenjia;Jin Yan
4 Dental Stem Cells and Tooth Regeneration. 期刊论文 Shuai Yi;Ma Yang;Guo Tao;Zhang Liqiang;Yang Rui;Qi Meng;Liu Wenjia;Jin Yan
5 Increased autophagy is required to protect periodontal ligament stem cells from apoptosis in inflammatory microenvironment. 期刊论文 an ying;liu wenjia;xue peng;zhang yongjie;wang qintao;jin yan
6 Alkaline Phosphatase Controls Lineage Switching of Mesenchymal Stem Cells by Regulating the LRP6/GSK3β Complex in Hypophosphatasia 期刊论文 wenjialiu;liqiang Zhang
7 Mechanical stress regulates osteogenic differentiation and RANKL/OPG ratio in periodontal ligament stem cells by the Wnt/beta-catenin pathway 期刊论文 Zhang Liqiang;Liu Wenjia;Zhao Jiangdong;Ma Xiaojie;Shen Lin;Zhang Yongjie;Jin Fang;Jin Yan
8 Increased autophagy is required to protect periodontal ligament stem cells from apoptosis in inflammatory microenvironment 期刊论文 An Ying;Liu Wenjia;Xue Peng;Zhang Yongjie;Wang Qintao;Jin Yan
9 Autophagy controls mesenchymal stem cell properties and senescence during bone aging 期刊论文 Ma Yang;Qi Meng;An Ying;Zhang Liqiang;Yang Rui;Doro Daniel H.;Liu Wenjia;Jin Yan
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