血管紧张素II-1型受体自身抗体致子痫前期胎盘血管功能失稳态的分子机制研究

91539205
2015
H0211.血管发生及血管结构与功能异常
刘慧荣
重大研究计划
教授
首都医科大学
230万元
胎盘血管;钾通道;血管紧张素Ⅱ-1型受体;不脱敏;自身抗体
2016-01-01到2019-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Isolation and Culture of Vascular Smooth Muscle Cells from Rat Placenta 期刊论文 Chunyu He;Meili Wang;Zi Yan;Suli Zhang;Huirong Liu
2 Limited AT1 Receptor Internalization Is a Novel Mechanism Underlying Sustained Vasoconstriction Induced by AT1 Receptor Autoantibody from Preeclampsia 期刊论文 Jingwei Bian;Jinghui Lei;Xiaochen Yin;Pengli Wang;Ye Wu;Xiaoli Yang;Li Wang;Suli Zhang;Huirong Liu
3 孕鼠胎盘血管平滑肌细胞的分离及传代方法 专利 刘慧荣;贺春雨;张苏丽;王美丽;白丽娜;王鹏丽
4 Hyperinsulinemia precedes insulin resistance in offspring rats exposed to angiotensin II type 1 autoantibody in utero 期刊论文 Zhang S;Wei M;Yue M;Wang P;Yin X;Wang L;Yang X;Liu H
5 Angiotensin II inhibits apoptosis of mouse aortic smooth muscle cells through regulating the circNRG-1/miR-193b-5p/NRG-1 axis 期刊论文 Yan Sun;Suli Zhang;Mingming Yue;Yang Li;Jing Bi;Huirong Liu
6 Long-term presence of angiotensin II type 1 receptor autoantibody reduces aldosterone production by triggering Ca2+ overload in H295R cells 期刊论文 Jinghui Lei;Suli Zhang;Pengli Wang;Yang Liao;Jingwei Bian;Xiaochen Yin;Ye Wu;Lina Bai;Feng Wang;Xiaoli Yang;Huirong Liu
7 Autoantibodies against AT1 receptor contribute to vascular aging and endothelial cell senescence 期刊论文 Meili Wang;Xiaochen Yin;Suli Zhang;Chenfeng Mao;Ning Cao;Xiaochun Yang;Jingwei Bian;Weiwei Hao;Qian Fan;Huirong Liu
8 The role of NO-cGMP pathway inhibition in vascular endothelial-dependent smooth muscle relaxation disorder of AT1-AA positive rats: Protective effects of adiponectin 期刊论文 Zhiyuan Wang;Ye Wu;Suli Zhang;Yuhui Zhao;Xiaochen Yin;Wen Wang;Xinliang Ma;Huirong Liu
9 The mechanisms behind decreased internalization of angiotensin II type 1 receptor 期刊论文 Jingwei Bian;Suli Zhang;Ming Yi;Mingming Yue;Huirong Liu
10 The Prognostic Role of Angiotensin II Type 1 Receptor Autoantibody in Non-Gravid Hypertension and Pre-eclampsia: A Meta-analysis and Our Studies 期刊论文 Lei Jinghui;Li Yafeng;Zhang Suli;Wu Ye;Wang Pengli;Liu Huirong
11 第四届全国大学生基础医学创新论坛暨实验设计大赛 奖励 边经纬;尹晓辰;贺春雨;刘慧荣;张苏丽
12 β2-adrenergic receptor autoantibodies alleviated myocardial damage induced by β1-adrenergic receptor autoantibodies in heart failure 期刊论文 Ning Cao;Hao Chen;Yan Bai;Xiaochun Yang;Wenli Xu;Weiwei Hao;Yi Zhou;Jiayin Chai;Ye Wu;Zhaojia Wang;Xiaochen Yin;Li Wang;Wen Wang;Huirong Liu
13 血管紧张素Ⅱ-1型受体自身抗体通过激活心肌成纤维细胞参与心肌纤维化 期刊论文 郝韦韦;张苏丽;孙艳;白丽娜;边经纬;于海存;尹晓辰;王鹏丽;刘慧荣
14 Increase in G protein-coupled receptor autoantibodies with decline of cardiac function in hypercholesterolemic rats 期刊论文 Li Y;Tian J;Ma XR;Li RT;Zhang SL;Wang PL;Yin XC;Bian JW;Lei JH;Liu HR
15 气动双推式乳化器 专利 刘慧荣;周震;张苏丽;尹晓辰;边经纬;陈卉;夏翃
16 Active immunization using hand-push emulsification method increases the operator's risk of transcutaneous immunization 期刊论文 Xiaochen Yin;Suli Zhang;Zhen Zhou;Jingwei Bian;Ye Wu;Pengli Wang;Yulin Gong;Lina Bai;Weiwei Hao;Xinliang Ma;Huirong Liu
17 The inhibitory effect of BKCa channels induced by autoantibodies against angiotensin II type 1 receptor is independent of AT1R 期刊论文 Peng Wang;Suli Zhang;Jie Ren;Li Yan;Lina Bai;Li Wang;Pengli Wang;Jingwei Bian;Xiaochen Yin;Huirong Liu
18 第五届全国大学生基础医学创新论坛暨实验设计大赛 奖励 翁文杰;隆罗莎;王彤彤;张苏丽;刘慧荣
19 The multiple effect of angiotensin II on regulating large-conductance Ca2+ and voltage-activated potassium channel in vascular smooth muscle cells 期刊论文 Yin Xiaochen;Zhang Suli;Liu Huirong
20 抗G蛋白偶联受体自身抗体在心血管疾病中的作用及相关机制探究 奖励 刘慧荣;张苏丽;王雯;王丽;闫莉;杜云辉;左琳;杨晓丽;赵荣瑞;吕婷婷
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