大麻素受体介导中性粒细胞参与肝脏炎症及纤维化的机制研究

81670550
2016
H0310.肝损伤、修复与再生
李丽英
面上项目
教授
首都医科大学
60万元
大麻素受体;固有免疫;肝纤维化;炎症;中性粒细胞
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Cannabinoid Receptor 1 Participates in Liver Inflammation by Promoting M1 Macrophage Polarization via RhoA/NF-kappa B p65 and ERK1/2 Pathways, Respectively, in Mouse Liver Fibrogenesis 期刊论文 Tian Lei;Li Weiyang;Yang Le;Chang Na;Fan Xiaoting;Ji Xiaofang;Xie Jieshi;Yang Lin;Li Liying
2 Neutrophils undergo switch of apoptosis to NETosis during murine fatty liver injury via S1P receptor 2 signaling 期刊论文 Xinhao Zhao;Le Yang;Na Chang;Lei Hou;Xuan Zhou;Lin Yang;Liying Li
3 Neutrophil recruitment mediated by sphingosine 1-phosphate (S1P)/S1P receptors during chronic liver injury 期刊论文 Zhao Xinhao;Yang Le;Chang Na;Hou Lei;Zhou Xuan;Dong Chengbin;Liu Fuquan;Yang Lin;Li Liying
4 Neutrophil Chemotaxis and NETosis in Murine Chronic Liver Injury via Cannabinoid Receptor 1/ Gi/o/ ROS/ p38 MAPK Signaling Pathway 期刊论文 Xuan Zhou;Le Yang;Xiaoting Fan;Xinhao Zhao;Na Chang;Lin Yang;Liying Li
5 Cannabinoid Receptor 1/miR-30b-5p Axis Governs Macrophage NLRP3 Expression and Inflammasome Activation in Liver Inflammatory Disease 期刊论文 Yang Le;Tian Lei;Zhang Zhi;Zhou Xuan;Ji Xiaofang;Liu Fuquan;Dong Chengbin;Hou Lei;Zhao Xinhao;Chang Na;Yang Lin;Li Liying
6 Both HuR and miR-29s regulate expression of CB1 involved in infiltration of bone marrow monocyte/macrophage in chronic liver injury 期刊论文 Chang Na;Duan Xianghui;Zhao Zhongxin;Tian Lei;Ji Xiaofang;Yang Lin;Li Liying
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