LOXL-1/Fibulin-5通过调控弹性蛋白交联及降解影响肝纤维化可逆性的机理

81670539
2016
H0310.肝损伤、修复与再生
尤红
面上项目
研究员
首都医科大学
60万元
肝纤维化;肝星状细胞;细胞外基质;弹性蛋白
2017-01-01到2020-12-31
  • 中英文摘要
  • 结题摘要
  • 结题报告
  • 项目成果
  • 项目参与人
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序号 标题 类型 作者
1 Quantitative assessment of liver fibrosis (qFibrosis) reveals precise outcomes in Ishak "stable" patients on anti-HBV therapy 期刊论文 Sun Yameng;Zhou Jialing;Wu Xiaoning;Chen Yongpeng;Piao Hongxin;Lu Lungen;Ding Huiguo;Nan Yuemin;Jiang Wei;Wang Tailing;Liu Hui;Ou Xiaojuan;Wee Aileen;Theise Neil D;Jia Jidong;You Hong
2 肝纤维化小鼠模型中弹性蛋白及其调控因子在肝纤维化形成和逆转中的分子机制 期刊论文 杨爱婷;严旭禛;赵文姗;李为雨;陈巍;尤红
3 Integrated analysis of microRNA and gene expression profiles reveals a functional regulatory module associated with liver fibrosis 期刊论文 Chen Wei;Zhao Wenshan;Yang Aiting;Xu Anjian;Wang Huan;Cong Min;Liu Tianhui;Wang Ping;You Hong
4 miRNA-150-5p promotes hepatic stellate cell proliferation and sensitizes hepatocyte apoptosis during liver fibrosis. 期刊论文 Chen Wei;Yan Xuzhen;Yang Aiting;Xu Anjian;Huang Tao;You Hong
5 Inhibition of lysyl oxidase-like 1 (LOXL1) expression arrests liver fibrosis progression in cirrhosis by reducing elastin crosslinking 期刊论文 Zhao Wenshan;Yang Aiting;Chen Wei;Wang Ping;Liu Tianhui;Cong Min;Xu Anjian;Yan Xuzhen;Jia Jidong;You Hong
6 非酒精性脂肪性肝病动物模型的研究 期刊论文 严旭禛;陈巍;杨爱婷;赵文姗;尤红
7 Dynamics of elastin in liver fibrosis: Accumulates late during progression and degrades slowly in regression. 期刊论文 Chen Wei;Yan Xuzhen;Xu Anjian;Sun Yameng;Wang Bingqiong;Huang Tao;Wang Huan;Cong Min;Wang Ping;Yang Aiting;Jia Jidong;You Hong
8 Multitranscriptome analyses reveal prioritized genes specifically associated with liver fibrosis progression independent of etiology. 期刊论文 Chen Wei;Wu Xiaoning;Yan Xuzhen;Xu Anjian;Yang Aiting;You Hong
9 基于SHG/TPEF检测小鼠肝脏弹性纤维方法的建立 期刊论文 陈巍;严旭禛;杨爱婷;黄涛;赵文姗;尤红
10 SHG/TPEF-based image technology improves liver fibrosis assessment of minimally sized needle biopsies 期刊论文 Wang Bingqiong;Sun Yameng;Zhou Jialing;Wu Xiaoning;Chen Shuyan;Shi Yiwen;Wu Shanshan;Liu Hui;Ren Yayun;Ou Xiaojuan;Jia Jidong;You Hong
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